Product image of Latanoprost E Timololo Aurobindo Italia (Timolol Maleate, Latanoprost) supplied by GNH India

Latanoprost E Timololo Aurobindo Italia

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latanoprost E Timololo Aurobindo Italia (Timolol Maleate, Latanoprost)

Timolol maleate and Latanoprost, the active ingredients in Latanoprost E Timololo Aurobindo Italia, are a beta‑blocker and a prostaglandin analog presented as eye drops for ocular use. They lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension.

GNH India supplies Latanoprost E Timololo Aurobindo Italia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma (Italia) S.R.L.

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Indications & Clinical Uses

Latanoprost E Timololo combines a beta‑blocker and a prostaglandin analog to manage intra‑ocular pressure in glaucoma‑related conditions.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers pressure to prevent conversion to glaucoma.
  • Post‑operative intra‑ocular pressure control: helps maintain target pressure after ocular surgery.

How It Works

  • Timolol maleate non‑selectively blocks β‑adrenergic receptors in the ciliary body, decreasing aqueous humor production. Latanoprost, a prostaglandin F2α analog, binds FP receptors in the uveoscleral pathway, enhancing outflow of aqueous humor. The combined actions result in a synergistic reduction of intra‑ocular pressure.

Side Effects

The following adverse reactions have been reported with the combination eye drops.

Common Side Effects

  • Eye irritation: transient burning or stinging after instillation.
  • Blurred vision: temporary visual disturbance.
  • Redness of the eye: conjunctival hyperemia.
  • Itching or discomfort: mild pruritus around the ocular surface.
  • Dry eye sensation: reduced tear film stability.
  • Foreign body sensation: feeling of something in the eye.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or anaphylaxis.
  • Worsening of glaucoma: unexpected rise in intra‑ocular pressure.
  • Chest pain or palpitations: systemic β‑blocker effects.
  • Bradycardia: markedly reduced heart rate.
  • Severe eye inflammation: uveitis or keratitis.
  • Systemic hypoglycaemia: especially in diabetic patients using β‑blockers.

Precautions & Warnings

Before using Latanoprost E Timololo, consider the following safety measures.

  • Pregnancy: consult a physician, as safety data are limited.
  • Breastfeeding: weigh potential risks versus benefits.
  • Cardiovascular disease: monitor heart rate and blood pressure.
  • Respiratory disease: avoid in patients with asthma or COPD due to β‑blockade.
  • Drug interactions: review concomitant medications for additive β‑blocker effects.
  • Store at room temperature: keep the bottle tightly closed, protect from light and moisture.

Avoid Interactions

Latanoprost E Timololo may interact with other medicines; categorize the risk level.

Major Interactions (Avoid)

  • Other ocular β‑blockers: may cause excessive systemic β‑blockade.
  • Systemic β‑agonists (e.g., albuterol): can reduce bronchodilator efficacy.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: may enhance blood‑pressure lowering effects.
  • Calcium channel blockers: possible additive cardiac effects.
  • Other prostaglandin analogs: increased risk of ocular hyperemia.
  • Non‑steroidal anti‑inflammatory eye drops: may alter prostaglandin metabolism.

Frequently Asked Questions

Latanoprost E Timololo is a combination eye‑drop containing timolol maleate and latanoprost. It is prescribed to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Timolol maleate is a non‑selective β‑adrenergic blocker. By blocking β‑receptors in the ciliary body, it reduces the production of aqueous humor, which lowers the pressure inside the eye.

The dosing regimen is determined by the prescribing ophthalmologist. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule and any adjustments are individualized based on patient response.

Safety data for use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The combination provides dual mechanisms—reduced aqueous humor production from timolol and increased outflow from latanoprost—offering greater intra‑ocular pressure reduction than either component alone. This can improve control in patients who need more than a single‑agent therapy.

Store the eye‑drops at room temperature, below 25 °C, in the original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any product that appears discolored or contaminated.

The medication is applied as an ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac of the prescribed eye(s). Avoid touching the dropper tip to any surface.

Serious adverse events include severe allergic reactions, unexpected rise in intra‑ocular pressure, systemic β‑blocker effects such as bradycardia or chest pain, and severe eye inflammation. Any of these symptoms require immediate medical attention.

Patients with known hypersensitivity to timolol, latanoprost, or any excipients should avoid the product. It is also contraindicated in individuals with severe sinus bradycardia, heart block, uncontrolled asthma, or those taking non‑selective β‑blockers systemically without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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