Product image of Latanoprost E Timololo Eg (Latanoprost, Timolol) supplied by GNH India

Latanoprost E Timololo Eg

Active Ingredient:
Latanoprost, Timolol
Origin:
EU

Latanoprost E Timololo Eg (Latanoprost, Timolol)

Latanoprost and Timolol, the active ingredients in Latanoprost Timolol, are a prostaglandin analog and a non‑selective beta blocker presented as ocular drops for eye use. The combination lowers intra‑ocular pressure and is indicated for open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanoprost Timolol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg S.P.A.

1
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Indications & Clinical Uses

Latanoprost Timolol is employed in the management of ocular conditions that require reduction of intra‑ocular pressure.

  • Open‑angle glaucoma: lowers eye pressure to prevent optic nerve damage and visual field loss.
  • Ocular hypertension: reduces elevated eye pressure to lower the risk of progression to glaucoma.

How It Works

  • Latanoprost increases uveoscleral outflow of aqueous humor by activating prostaglandin F receptors in the ciliary body, while Timolol blocks beta‑adrenergic receptors in the ciliary epithelium, decreasing aqueous humor production. The dual action results in a net reduction of intra‑ocular pressure.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation
  • Blurred vision
  • Redness of the conjunctiva
  • Dry eye or foreign‑body feeling

Serious or Rare Side Effects

  • Increased iris pigmentation
  • Periorbital fat atrophy
  • Corneal edema or ulceration
  • Severe allergic reaction (e.g., angio‑edema)
  • Systemic beta‑blocker effects such as bradycardia or bronchospasm

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Cardiovascular assessment: evaluate for bradycardia or heart block.
  • Respiratory status: avoid in patients with asthma or severe COPD.
  • Intra‑ocular pressure monitoring: ensure adequate pressure reduction after start.
  • Hypersensitivity check: discontinue if allergic reaction occurs.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Latanoprost Timolol may interact with several medicines.

Major Interactions (Avoid)

  • Non‑selective beta‑blocker antagonists (e.g., propranolol): additive systemic beta‑blockade.
  • Sympathomimetic eye drops (e.g., epinephrine): may diminish pressure‑lowering effect.
  • Carbonic anhydrase inhibitors: increased risk of ocular hypotension.
  • Other prostaglandin analogs: additive ocular side effects.

Moderate Interactions (Monitor Closely)

  • Systemic antihypertensives: monitor blood pressure for excessive lowering.
  • Bronchodilators: watch for bronchospasm in susceptible patients.
  • MAO inhibitors: potential interaction with timolol affecting heart rate.

Frequently Asked Questions

Latanoprost Timolol is a prescription eye drop indicated for the treatment of open‑angle glaucoma and ocular hypertension. By lowering intra‑ocular pressure, it helps prevent optic nerve damage and preserves visual function in adult patients.

Latanoprost, a prostaglandin analog, binds to FP receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor. Timolol, a non‑selective beta blocker, reduces aqueous production by blocking beta‑adrenergic receptors. Together they achieve a greater pressure‑lowering effect.

The dosing regimen is determined by the prescribing clinician based on the patient’s condition and response. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule should follow the prescriber’s instructions.

Safety data in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑agent prostaglandin analogs or beta blockers, the combination offers a synergistic pressure‑lowering effect, often achieving target intra‑ocular pressure with fewer drops. This can improve adherence but may increase the spectrum of ocular side effects.

Store the eye drops at room temperature, preferably below 25 °C. Keep the bottle in its original packaging, protect it from light and moisture, and discard any solution that appears discolored or contaminated.

The medication is applied as an ophthalmic solution. Tilt the head back, pull down the lower eyelid to form a pocket, and place one drop into the conjunctival sac without touching the bottle tip to the eye or lashes. Close the eye gently for a few seconds.

Serious adverse events include significant iris pigmentation changes, corneal edema, severe allergic reactions, and systemic beta‑blocker effects such as bradycardia, hypotension or bronchospasm. Patients should seek immediate medical attention if they experience these symptoms.

Contraindications include patients with known hypersensitivity to either component, those with severe asthma or chronic obstructive pulmonary disease, individuals with sinus bradycardia or advanced heart block, and patients with active ocular infections.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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