Product image of Latanoprost Fdc International (Latanoprost) supplied by GNH India

Latanoprost Fdc International

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Fdc International (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Fdc International, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It is employed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to preserve visual function.

GNH India supplies Latanoprost Fdc International as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and regulatory requirements across multiple markets.

Manufacturer / TM Owner

Fdc International Ltd

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Indications & Clinical Uses

  • Latanoprost is used in the management of ocular conditions that require reduction of intra‑ocular pressure.
  • Open‑angle glaucoma: lowers intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: reduces pressure to prevent conversion to glaucoma.
  • Secondary glaucoma (e.g., pseudoexfoliative): helps control pressure when other therapies are insufficient.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors on the ciliary muscle, activating a cascade that remodels the extracellular matrix and increases uveoscleral outflow of aqueous humor. The enhanced outflow reduces intra‑ocular pressure, providing therapeutic benefit in glaucomatous eyes.

Side Effects

Latanoprost may cause a range of ocular and systemic reactions.

Common Side Effects

  • Eye redness or hyperemia.
  • Eye irritation or foreign‑body sensation.
  • Blurred vision shortly after instillation.
  • Increased eyelash length and thickness.
  • Darkening of the iris color.
  • Periocular skin hyperpigmentation.

Serious or Rare Side Effects

  • Severe anterior uveitis or iritis.
  • Allergic contact dermatitis of the eyelid.
  • Significant visual acuity loss.
  • Ocular infection secondary to compromised surface.
  • Periorbital fat atrophy leading to cosmetic changes.

Precautions & Warnings

  • Before using Latanoprost, consider the following safety measures.
  • Monitor intra‑ocular pressure regularly: ensure therapeutic effect and detect over‑reduction.
  • Avoid contact lens wear for at least 15 minutes after instillation: reduce drug absorption by the lens.
  • Assess for pre‑existing ocular infections or inflammation: avoid exacerbation.
  • Caution in patients with corneal endothelial disease: may affect healing.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Latanoprost can interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent use of other prostaglandin analog eye drops: may increase risk of ocular irritation.
  • Recent ocular surgery: can impair wound healing.
  • Use with potent topical corticosteroids: may reduce efficacy.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: additive intra‑ocular pressure lowering effect; monitor pressure.
  • Carbonic anhydrase inhibitor eye drops: potential for excessive pressure reduction.
  • Systemic NSAIDs: may modestly affect prostaglandin pathways; observe for changes in response.

Frequently Asked Questions

Latanoprost is a prescription eye drop used to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension. By reducing pressure, it helps to prevent optic nerve damage and preserve visual function.

Latanoprost activates prostaglandin F (FP) receptors in the eye, which remodels the extracellular matrix and enhances uveoscleral outflow of aqueous humor. This increased outflow lowers intra‑ocular pressure, addressing the primary cause of glaucoma progression.

The dosing regimen for Latanoprost is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and timing should follow the prescriber’s instructions.

Safety data for Latanoprost in pregnancy and lactation are limited. It is classified as pregnancy category unknown, and use is generally reserved for situations where the potential benefit justifies any potential risk to the fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost belongs to the prostaglandin analog class, which typically offers once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blocker or carbonic anhydrase inhibitor drops, prostaglandin analogs often have a more favorable dosing convenience and comparable efficacy.

Latanoprost eye drops should be stored at room temperature, below 25 °C, in the original packaging. Protect the bottle from moisture and direct sunlight. Do not freeze the product, and keep the tip clean to avoid contamination.

Latanoprost is administered as a sterile ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac. Close the eye gently for a few seconds and avoid blinking excessively.

Serious risks, though rare, include severe anterior uveitis, allergic reactions affecting the eyelid or conjunctiva, significant loss of visual acuity, and ocular infection. Patients should seek immediate medical attention if they experience pain, redness, vision changes, or swelling.

Latanoprost should be avoided in patients with known hypersensitivity to the drug or any of its excipients, those who have had recent ocular surgery, or individuals with active ocular infections. Caution is also advised for patients with corneal endothelial disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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