Product image of Latanoprost Macarthys Laboratories (Latanoprost) supplied by GNH India

Latanoprost Macarthys Laboratories

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Macarthys Laboratories (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Macarthys Laboratories, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It lowers intra‑ocular pressure by increasing uveoscleral outflow, and is indicated for the treatment of open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanoprost Macarthys Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide through regulated distribution channels. The company adheres to stringent quality standards and supports customers with technical and regulatory assistance.

Manufacturer / TM Owner

Macarthys Laboratories Ltd

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Indications & Clinical Uses

Latanoprost is a prostaglandin analog used to reduce intra‑ocular pressure in glaucoma and ocular hypertension.

  • Open-angle glaucoma: reduces intra‑ocular pressure, helping to prevent optic nerve damage.
  • Ocular hypertension: lowers elevated intra‑ocular pressure to reduce the risk of progression to glaucoma.
  • Secondary open-angle glaucoma: improves fluid outflow to control pressure in secondary forms of the disease.

How It Works

  • Latanoprost is a synthetic analogue of prostaglandin F2α that binds to FP receptors on the ciliary muscle. Receptor activation remodels the extracellular matrix, enhancing uveoscleral outflow of aqueous humor. The increased outflow reduces intra‑ocular pressure, providing therapeutic control of glaucoma and ocular hypertension. The drug is administered as a single drop in the affected eye once daily, and its effect persists for 24 hours.

Side Effects

Latanoprost may cause ocular and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Darkening of iris: gradual brownish pigmentation.

Serious or Rare Side Effects

  • Inflammatory eye reactions: uveitis or iritis.
  • Corneal edema: swelling of the cornea.
  • Vision loss: sudden decrease in visual acuity.

Precautions & Warnings

Latanoprost should be used with careful clinical oversight.

  • Patient assessment: evaluate intra‑ocular pressure and ocular health before initiating therapy.
  • Contraindications: avoid use in patients with known hypersensitivity to latanoprost or any component of the formulation.
  • Monitoring: schedule regular eye examinations to detect changes in iris color or eyelash growth.
  • Drug interactions: inform prescriber of concurrent use of other prostaglandin analogues or ocular medications.
  • Pregnancy and lactation: safety not established; use only if potential benefit justifies potential risk.
  • Store at ambient temperature: keep the bottle in the original packaging, protect from light and freeze.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Non‑steroidal anti‑inflammatory eye drops: may reduce efficacy of latanoprost.
  • Systemic prostaglandin analogues: increased risk of systemic side effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: additive intra‑ocular pressure lowering effect.
  • Corticosteroid eye drops: may counteract pressure‑lowering effect.
  • Anticholinergic agents: potential for altered ocular surface.

Frequently Asked Questions

Latanoprost Macarthys Laboratories is an ophthalmic solution containing the prostaglandin analog latanoprost. It is prescribed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Latanoprost mimics prostaglandin F2α and binds to FP receptors in the ciliary body. This triggers remodeling of extracellular matrix proteins, which increases uveoscleral outflow of aqueous humor. The enhanced outflow reduces intra‑ocular pressure, addressing the primary cause of glaucoma progression.

The prescribed dose of latanoprost is determined by the treating ophthalmologist based on the patient’s intra‑ocular pressure, severity of disease, and response to therapy. Typically, one drop is instilled in the affected eye(s) once daily, but the exact regimen is individualized by the prescriber.

Safety data for latanoprost in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. It should be used only if the potential benefit outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The team then provides pricing, availability, shipping details and any required import documentation.

Latanoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blockers or carbonic anhydrase inhibitors, prostaglandin analogues often achieve greater pressure lowering with a favorable dosing schedule, though individual response and side‑effect profiles vary.

Latanoprost ophthalmic solution should be stored at ambient temperature, protected from light and freezing. Keep the bottle tightly closed in its original packaging, and avoid exposing it to excessive heat or moisture. Discard any solution that appears discolored or contains particles.

Latanoprost is administered as a single drop placed in the conjunctival sac of the affected eye(s) once daily, usually in the evening. Patients should wash their hands, avoid touching the tip of the bottle, and wait a few minutes before applying other eye drops to ensure proper absorption.

Serious risks, though rare, include inflammatory eye conditions such as uveitis or iritis, corneal edema, and sudden loss of visual acuity. Patients should report any severe eye pain, redness, vision changes, or allergic reactions promptly to their eye care professional.

Latanoprost should not be used by individuals with known hypersensitivity to latanoprost or any excipients in the formulation. Caution is advised for patients with active ocular infections, severe inflammation, or a history of adverse reactions to prostaglandin analogues. The prescriber will assess suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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