Product image of Latanoprost Sandoz (Latanoprost) supplied by GNH India

Latanoprost Sandoz

Active Ingredient:
Latanoprost
Origin:
EU

Latanoprost Sandoz (Latanoprost)

Latanoprost, the active ingredient in Latanoprost Sandoz, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It increases uveoscleral outflow of aqueous humor, thereby reducing intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension.

GNH India supplies Latanoprost Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide under EU quality standards. The company manages regulatory compliance, secure logistics and reliable batch release for global distribution, and timely delivery to meet client needs.

Manufacturer / TM Owner

Sandoz S.P.A.

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Indications & Clinical Uses

  • Latanoprost is a prostaglandin analog used to lower intra‑ocular pressure in glaucoma and ocular hypertension.
  • Open‑angle glaucoma: reduces intra‑ocular pressure and helps preserve visual field.
  • Ocular hypertension: lowers pressure to prevent progression to glaucoma.
  • Secondary open‑angle glaucoma: improves outflow and decreases pressure in secondary forms of the disease.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors on the ciliary muscle, activating a signaling cascade that remodels the extracellular matrix and enhances uveoscleral outflow of aqueous humor. The increased outflow lowers intra‑ocular pressure, addressing the primary pathophysiological driver of glaucomatous optic nerve damage.

Side Effects

Latanoprost may cause ocular and peri‑ocular reactions.

Common Side Effects

  • Eye redness or hyperemia.
  • Increased eyelash length and thickness.
  • Darkening of the iris pigment.
  • Mild eye irritation or foreign‑body sensation.
  • Blurred vision after instillation.
  • Dry eye sensation.

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angio‑edema, anaphylaxis).
  • Uveitis or intra‑ocular inflammation.
  • Macular edema, especially in patients with risk factors.
  • Paradoxical increase in intra‑ocular pressure.
  • Corneal edema or keratitis.
  • Endophthalmitis or infectious keratitis.

Precautions & Warnings

  • Before prescribing Latanoprost, clinicians should consider several safety aspects.
  • Assess intra‑ocular pressure baseline: ensure accurate measurement prior to therapy.
  • Monitor iris color changes: inform patients that permanent darkening may occur.
  • Avoid use in active ocular inflammation: prostaglandin analogs can exacerbate inflammation.
  • Inform about eyelash growth: patients should be aware of cosmetic changes.
  • Store at room temperature: keep bottle in original packaging, protect from light and moisture.

Avoid Interactions

Latanoprost can interact with other ophthalmic agents, requiring attention to combination therapy.

Major Interactions (Avoid)

  • Concurrent prostaglandin analogs: additive ocular effects may increase irritation.
  • Ocular anesthetics: combined use may heighten corneal toxicity.
  • Systemic beta‑blockers: additive intra‑ocular pressure reduction; monitor closely.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: may diminish latanoprost efficacy.
  • Contact lens wear: risk of drug deposition on lenses.
  • Anticholinergic eye drops: possible reduction in aqueous outflow enhancement.

Frequently Asked Questions

Latanoprost Sandoz is an ophthalmic solution indicated for the reduction of intra‑ocular pressure in patients with open‑angle glaucoma and ocular hypertension. By lowering pressure, it helps to prevent optic nerve damage and preserve visual function.

Latanoprost is a prostaglandin F (FP) receptor agonist. Activation of FP receptors on the ciliary body leads to remodeling of the extracellular matrix, which enhances uveoscleral outflow of aqueous humor. The increased outflow reduces intra‑ocular pressure, addressing the primary cause of glaucoma progression.

The dosing regimen is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily, often in the evening, but the exact schedule should follow the prescriber’s instructions.

Safety data for Latanoprost during pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

Enquiries can be submitted on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

The primary alternative class is beta‑blocker eye drops such as timolol. While beta‑blockers reduce aqueous humor production, latanoprost increases uveoscleral outflow. Latanoprost often provides greater pressure reduction with once‑daily dosing, but beta‑blockers may be preferred in patients with contraindications to prostaglandins.

Store the ophthalmic solution at room temperature, below 25 °C, in the original container. Protect the bottle from direct light and moisture, and keep the tip clean to avoid contamination. Do not freeze the product.

Instill one drop into the prescribed eye(s) using the provided dropper. The drop should be placed on the lower conjunctival sac without touching the tip to the ocular surface. Patients are usually advised to administer the drop in the evening and to avoid blinking excessively for a few minutes.

Serious but rare risks include severe allergic reactions, uveitis, macular edema, paradoxical increase in intra‑ocular pressure, and corneal edema. Patients should seek immediate medical attention if they experience sudden vision loss, severe eye pain, redness, or signs of infection.

Latanoprost should be avoided in individuals with active ocular inflammation, known hypersensitivity to latanoprost or any component of the formulation, and in patients who have experienced severe adverse reactions to prostaglandin analogs. Contraindications must be confirmed by the prescribing clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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