Product image of Latanoprost/Timolol Eg (Timolol Maleate, Latanoprost) supplied by GNH India

Latanoprost/Timolol Eg

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latanoprost/Timolol Eg (Timolol Maleate, Latanoprost)

Latanoprost and Timolol, the active ingredients in Latanoprost/Timolol Eg, are a prostaglandin analog and beta‑blocker combination presented as eye drops for ocular use. It treats open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanoprost/Timolol Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Latanoprost/Timolol Eg is used in the management of ocular conditions that require reduction of intra‑ocular pressure.

  • Open‑angle glaucoma: lowers intra‑ocular pressure to prevent optic nerve damage.
  • Ocular hypertension: reduces elevated eye pressure to lower the risk of developing glaucoma.
  • Secondary open‑angle glaucoma: assists in controlling pressure when glaucoma is associated with other ocular diseases.

How It Works

  • Latanoprost, a prostaglandin F2α analogue, increases uveoscleral outflow of aqueous humor, while timolol maleate, a non‑selective β‑adrenergic antagonist, decreases aqueous humor production by blocking β‑receptors in the ciliary body. The combined actions result in a net reduction of intra‑ocular pressure.

Side Effects

The following adverse reactions have been reported with Latanoprost/Timolol eye drops.

Common Side Effects

  • Eye irritation or burning sensation.
  • Blurred vision shortly after instillation.
  • Conjunctival hyperemia (red eye).
  • Itching or mild allergic response on the eyelid.
  • Dry eye or foreign‑body sensation.
  • Increased eyelash growth.

Serious or Rare Side Effects

  • Severe allergic reaction (angio‑edema, anaphylaxis).
  • Worsening of glaucoma or sudden loss of vision.
  • Chest pain or marked bradycardia.
  • Bronchospasm or severe respiratory difficulty.
  • Persistent eye pain or corneal ulceration.
  • Vision loss requiring immediate medical attention.

Precautions & Warnings

Before using Latanoprost/Timolol eye drops, consider the following precautions.

  • Pregnancy: safety not established; use only if potential benefit justifies the risk.
  • Breastfeeding: unknown excretion in milk; weigh benefits against possible risks.
  • Respiratory disease: avoid in patients with asthma or chronic obstructive pulmonary disease.
  • Cardiovascular disease: monitor heart rate and blood pressure; contraindicated in severe bradycardia.
  • Drug interactions: be cautious when co‑administering other beta‑blockers or prostaglandin analogues.
  • Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

Latanoprost/Timolol may interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Systemic non‑selective beta‑blockers: additive bradycardia and hypotension.
  • Other intra‑ocular pressure‑lowering prostaglandin analogues: risk of excessive pressure reduction.
  • Asthma or COPD reliever inhalers (β‑agonists): may diminish therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Systemic antihypertensives: monitor for enhanced hypotensive response.
  • Calcium channel blockers: observe for bradycardia.
  • Anticholinergic eye drops: may affect ocular surface tolerance.
  • Topical ocular anesthetics: potential for delayed wound healing.

Frequently Asked Questions

Latanoprost/Timolol Eg is a prescription ophthalmic solution used to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Latanoprost increases the outflow of aqueous humor through the uveoscleral pathway, while Timolol reduces the production of aqueous humor by blocking β‑adrenergic receptors in the ciliary body. Together they provide a synergistic reduction in eye pressure.

The dosing regimen is determined by the prescribing clinician. Typically, one drop is instilled in the affected eye(s) once daily, but the exact dose and frequency should follow the healthcare professional’s instructions.

Safety data for Latanoprost/Timolol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The combination offers dual mechanisms—enhanced outflow from Latanoprost and reduced production from Timolol—resulting in greater intra‑ocular pressure reduction than either component alone. This can improve treatment efficacy for patients who need more robust pressure control.

Store the eye‑drop bottle at room temperature, preferably below 25 °C, in the original container. Keep it tightly closed, protect from light, and avoid exposure to moisture. Do not freeze the product.

The solution is applied topically as a single drop into the conjunctival sac of the prescribed eye(s) once daily, usually in the evening. Patients should wash their hands before use, avoid touching the tip of the bottle to any surface, and wait several minutes before applying other eye medications.

Serious risks include severe allergic reactions, significant bradycardia or hypotension, bronchospasm in susceptible individuals, and sudden worsening of glaucoma or loss of vision. Any of these symptoms require immediate medical attention.

Patients with known hypersensitivity to either component, severe asthma or chronic obstructive pulmonary disease, significant bradycardia, sinus node dysfunction, or those taking systemic non‑selective beta‑blockers should avoid this medication unless a specialist determines it is safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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