Product image of Latanoprost/Timolol Eg (Latanoprost, Timolol) supplied by GNH India

Latanoprost/Timolol Eg

Active Ingredient:
Latanoprost, Timolol
Origin:
EU

Latanoprost/Timolol Eg (Latanoprost, Timolol)

Latanoprost, the active ingredient in Latanoprost/Timolol Eg, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It is combined with timolol, a non‑selective beta‑blocker, to lower intra‑ocular pressure in patients with open‑angle glaucoma and ocular hypertension.
GNH India supplies Latanoprost/Timolol Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Latanoprost/Timolol acts on ocular pressure regulation pathways to manage glaucoma‑related conditions.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent conversion to glaucoma.
  • Secondary open‑angle glaucoma: helps control pressure when other causes are present.

How It Works

  • Latanoprost increases uveoscleral outflow of aqueous humor by activating prostaglandin F receptors in the ciliary body, while timolol blocks β‑adrenergic receptors in the ciliary epithelium, decreasing aqueous humor production. The combined effect results in a net reduction of intra‑ocular pressure.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness of the conjunctiva.
  • Blurred vision shortly after instillation.
  • Increased eyelash growth or darkening of the iris.

Serious or Rare Side Effects

  • Allergic reaction with swelling or severe eye pain.
  • Sudden loss of vision.
  • Systemic beta‑blocker effects such as bradycardia, bronchospasm, or hypotension.

Precautions & Warnings

Before using Latanoprost/Timolol, consider the following precautions.

  • Cardiac assessment: evaluate for bradycardia or heart block.
  • Respiratory status: avoid in patients with asthma or severe COPD.
  • Systemic beta‑blocker use: monitor for additive cardiovascular effects.
  • Ocular conditions: discontinue if severe eye inflammation occurs.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Store below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Latanoprost/Timolol may interact with other medications as described below.

Major Interactions (Avoid)

  • Non‑selective beta‑agonists (e.g., albuterol): may reduce timolol efficacy.
  • Systemic beta‑blockers: risk of additive bradycardia or hypotension.
  • Other prostaglandin analogs: increased risk of ocular irritation.

Moderate Interactions (Monitor Closely)

  • Additional ocular hypotensive agents: monitor intra‑ocular pressure closely.
  • Topical NSAIDs: may exacerbate corneal irritation.
  • MAO inhibitors: observe for systemic cardiovascular effects.

Frequently Asked Questions

Latanoprost/Timolol Eg is a prescription ophthalmic solution used to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension. By reducing eye pressure, it helps prevent optic nerve damage and visual field loss associated with these conditions.

Latanoprost, a prostaglandin analog, binds to FP receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor. This increased drainage lowers intra‑ocular pressure, complementing timolol’s reduction of fluid production.

The prescribed dose is determined by the treating ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily, but the exact regimen should follow the clinician’s instructions and the product label.

Safety data in pregnancy and lactation are limited. The medication should be used only if the potential benefit justifies the potential risk to the fetus or infant. Physicians should discuss individual circumstances with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with monotherapy agents, the combination offers dual mechanisms—enhanced outflow via latanoprost and reduced production via timolol—often achieving greater pressure reduction with a single drop. This can improve adherence versus using two separate eye drops.

Store the ophthalmic solution below 25 °C in its original container, protecting it from light and moisture. Do not freeze. Keep the bottle tightly closed when not in use and discard any solution that appears discolored or contaminated.

The medication is administered as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.

Serious risks include severe allergic reactions, sudden vision loss, and systemic beta‑blocker effects such as bradycardia, hypotension, or bronchospasm, especially in patients with underlying cardiac or respiratory disease. Prompt medical attention is required if these occur.

Patients with known hypersensitivity to latanoprost, timolol, or any excipients should avoid the product. It is also contraindicated in individuals with severe asthma, chronic obstructive pulmonary disease, bradycardia, or heart block unless closely monitored by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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