Product image of Latanoprost/Timolol Elvim (Timolol Maleate, Latanoprost) supplied by GNH India

Latanoprost/Timolol Elvim

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latanoprost/Timolol Elvim (Timolol Maleate, Latanoprost)

Timolol maleate, the active ingredient in Latanoprost/Timolol Elvim, is a beta blocker presented as an ophthalmic solution for ocular use. It is combined with latanoprost, a prostaglandin analog, to treat elevated intra‑ocular pressure in open‑angle glaucoma and ocular hypertension.

GNH India supplies Latanoprost/Timolol Elvim as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sia Elvim

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Indications & Clinical Uses

  • Latanoprost/Timolol acts on the ocular pressure regulation pathway to lower intra‑ocular pressure in glaucoma‑related conditions.
  • Open‑angle glaucoma: lowers intra‑ocular pressure to prevent optic nerve damage.
  • Ocular hypertension: reduces pressure to prevent progression to glaucoma.
  • Elevated intra‑ocular pressure: maintains target pressure to protect visual field.

How It Works

  • Latanoprost increases uveoscleral outflow of aqueous humor by activating prostaglandin F receptors, while timolol maleate blocks beta‑adrenergic receptors in the ciliary body, decreasing aqueous humor production. The combined effect results in a greater reduction of intra‑ocular pressure than either component alone.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation
  • Blurred vision
  • Redness of the eye
  • Itching or mild discomfort
  • Dry eye sensation
  • Foreign body feeling

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., swelling, rash)
  • Persistent eye pain or inflammation
  • Sudden loss of vision
  • Marked bradycardia or heart block
  • Bronchospasm or respiratory difficulty
  • Systemic hypotension

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Cardiovascular assessment: evaluate heart rate and rhythm.
  • Respiratory status: avoid in patients with severe asthma or COPD.
  • Concomitant beta‑blocker use: monitor for additive bradycardia.
  • Pregnancy: category unknown; use only if benefit outweighs risk.
  • Breastfeeding: caution as drug may be excreted in milk.
  • Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

Latanoprost/Timolol may interact with other medications as follows:

Major Interactions (Avoid)

  • Other ocular beta‑blockers: additive bradycardia and hypotension.
  • Non‑selective systemic beta‑blockers: increased risk of cardiac depression.
  • Sympathomimetic eye drops (e.g., phenylephrine): reduced efficacy of timolol.

Moderate Interactions (Monitor Closely)

  • Systemic antihypertensives: monitor blood pressure for additive lowering.
  • Anticholinergic eye drops: may diminish prostaglandin effect.
  • Calcium channel blockers: watch for enhanced hypotensive response.

Frequently Asked Questions

Latanoprost/Timolol Elvim is an ophthalmic solution indicated for the reduction of intra‑ocular pressure in patients with open‑angle glaucoma and ocular hypertension. By lowering pressure, it helps prevent optic nerve damage and visual field loss associated with these conditions.

The timolol component blocks beta‑adrenergic receptors in the ciliary body, decreasing aqueous humor production. Latanoprost, a prostaglandin analog, enhances uveoscleral outflow of aqueous humor. Together, they provide a synergistic reduction of intra‑ocular pressure.

The prescribed dose is determined by the treating ophthalmologist based on the patient’s condition and response. Typically, one drop is instilled into the affected eye(s) once daily, but the exact regimen should follow the prescriber’s instructions.

The pregnancy category for this combination is unknown, and safety data are limited. It should only be used if the potential benefit justifies the potential risk to the fetus. Caution is advised during breastfeeding, as the drug may be excreted in milk.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After verification of trade or institutional credentials, the team will provide pricing, availability, shipping details, and any required import documentation.

Compared with single‑agent therapies, the combination offers greater intra‑ocular pressure reduction than either timolol or latanoprost alone. It may be preferred when monotherapy does not achieve target pressure, reducing the need for multiple eye drops and improving patient adherence.

Store the eye‑drop bottle at room temperature, below 25 °C. Keep it tightly closed, protect from light, and avoid exposure to moisture. Do not freeze the product.

The medication is applied as a single drop into the affected eye(s) once daily, preferably in the evening. The patient should avoid touching the tip of the bottle to the eye or any other surface to maintain sterility.

Serious risks include severe allergic reactions, sudden loss of vision, marked bradycardia, bronchospasm, and systemic hypotension. Patients should seek immediate medical attention if they experience any of these symptoms.

The product should be avoided in patients with known hypersensitivity to timolol, latanoprost, or any excipients, as well as those with severe asthma, chronic obstructive pulmonary disease, sinus bradycardia, or certain cardiac conduction disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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