Product image of Latanoprost/Timolol Elvim (Timolol Maleate, Latanoprost) supplied by GNH India

Latanoprost/Timolol Elvim

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latanoprost/Timolol Elvim (Timolol Maleate, Latanoprost)

Timolol maleate, the active ingredient in Latanoprost/Timolol Elvim, is a prostaglandin analog and beta‑adrenergic blocker presented as eye drops for ocular use. It treats open‑angle glaucoma and ocular hypertension by lowering intra‑ocular pressure in adult patients.\n\nGNH India supplies Latanoprost/Timolol Elvim as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sia Elvim

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Indications & Clinical Uses

  • Latanoprost/Timolol is a combination ophthalmic therapy used to manage conditions that involve elevated intra‑ocular pressure.\n\nOpen‑angle glaucoma: reduces intra‑ocular pressure to slow optic nerve damage.\nOcular hypertension: lowers pressure to prevent progression to glaucoma.\nPost‑surgical ocular pressure control: helps maintain target pressure after glaucoma filtration surgery.

How It Works

  • Latanoprost, a prostaglandin F2α analogue, increases uveoscleral outflow of aqueous humor by remodeling extracellular matrix in the ciliary body. Timolol maleate, a non‑selective beta‑adrenergic blocker, reduces aqueous humor production by inhibiting beta‑1 and beta‑2 receptors in the ciliary epithelium. The combined actions result in a synergistic reduction of intra‑ocular pressure.

Side Effects

  • The following adverse reactions have been reported with the combination eye drops.\n\nCommon Side Effects:\n- Eye irritation or burning sensation\n- Blurred vision shortly after instillation\n- Conjunctival hyperemia (redness)\n- Increased eyelash growth\n- Darkening of iris pigmentation\n- Foreign body sensation\n\nSerious or Rare Side Effects:\n- Severe allergic reaction (e.g., angio‑edema)\n- Chest pain or palpitations\n- Shortness of breath or bronchospasm\n- Sudden loss of vision\n- Severe eye pain or inflammation\n- Cardiac arrhythmias

Precautions & Warnings

  • Before prescribing Latanoprost/Timolol, clinicians should consider the following precautions.\n\nCardiovascular assessment: evaluate heart rate and rhythm, especially in patients with bradycardia.\nRespiratory status: avoid in patients with asthma or severe chronic obstructive pulmonary disease.\nSinus node dysfunction: use with caution in patients with sick sinus syndrome.\nPregnancy and lactation: safety not established; weigh potential benefits against risks.\nOcular reaction: discontinue if severe inflammation or allergic response occurs.\nStore at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

  • Latanoprost/Timolol may interact with other systemic or ocular agents.\n\nMajor Interactions (Avoid):\n- Non‑selective beta‑blockers (e.g., propranolol): additive bradycardia or hypotension.\n- Other prostaglandin analogues: increased risk of ocular hyperemia and iris pigmentation.\n- MAO inhibitors: potential for exaggerated cardiovascular effects.\n\nModerate Interactions (Monitor Closely):\n- Calcium channel blockers: may enhance intra‑ocular pressure‑lowering effect.\n- Inhaled beta‑agonists (e.g., albuterol): may reduce timolol efficacy.\n- Systemic steroids: possible attenuation of prostaglandin effect.

Frequently Asked Questions

Latanoprost/Timolol Elvim is an ophthalmic combination of a prostaglandin analogue and a beta‑blocker used to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Timolol maleate is a non‑selective beta‑adrenergic blocker that reduces the production of aqueous humor by inhibiting beta‑1 and beta‑2 receptors in the ciliary body, thereby contributing to a decrease in intra‑ocular pressure.

The prescribed dose is determined by the treating ophthalmologist. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but the exact regimen should follow the clinician’s instructions.

Safety in pregnancy and lactation has not been established. The prescriber must weigh potential benefits against possible risks and consider alternative treatments if appropriate.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

The combination offers complementary mechanisms—Latanoprost increases outflow of aqueous humor while Timolol decreases its production—resulting in a greater overall reduction of intra‑ocular pressure than either agent used separately, often allowing once‑daily dosing.

Store the eye‑drop bottles at room temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect from light and moisture, and discard any product that appears discolored or contains particles.

The medication is applied as a single drop to each prescribed eye, usually in the evening. Patients should wash their hands before use, avoid touching the tip of the bottle to the eye or any surface, and wait at least five minutes before applying other eye medications.

Serious risks include severe allergic reactions such as angio‑edema, significant cardiac events like chest pain or arrhythmias, bronchospasm in susceptible individuals, and sudden loss of vision. Any of these symptoms require immediate medical attention.

Patients with known hypersensitivity to either component, those with severe asthma, chronic obstructive pulmonary disease, sinus node dysfunction, bradycardia, or uncontrolled heart failure should avoid this medication unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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