Product image of Latanoprost/Timolol Olikla (Timolol Maleate, Latanoprost) supplied by GNH India

Latanoprost/Timolol Olikla

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latanoprost/Timolol Olikla (Timolol Maleate, Latanoprost)

Timolol maleate and latanoprost, the active ingredient in Latanoprost/Timolol Olikla, is a beta‑blocker and prostaglandin analog presented as eye drops for ocular use. It treats open‑angle glaucoma and ocular hypertension in adults.

GNH India supplies Latanoprost/Timolol Olikla as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Olikla S.R.O.

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Indications & Clinical Uses

Latanoprost/Timolol Olikla is used in the management of ocular conditions that require reduction of intra‑ocular pressure.

  • Open‑angle glaucoma: lowers intra‑ocular pressure to prevent optic nerve damage.
  • Ocular hypertension: reduces pressure to decrease risk of developing glaucoma.
  • Secondary glaucoma (e.g., pseudoexfoliative): helps control pressure when other therapies are insufficient.

How It Works

  • Latanoprost, a prostaglandin analog, increases uveoscleral outflow of aqueous humor, enhancing drainage from the eye. Timolol maleate, a non‑selective beta‑adrenergic blocker, reduces aqueous humor production by inhibiting beta‑receptors in the ciliary body. The combined effect results in a greater and more consistent reduction of intra‑ocular pressure than either agent alone.

Side Effects

The following adverse reactions have been reported with Latanoprost/Timolol Olikla.

Common Side Effects

  • Eye irritation or burning sensation.
  • Blurred vision.
  • Redness of the conjunctiva.
  • Itching or mild allergic response.
  • Dry eye or foreign body sensation.
  • Temporary changes in eyelash growth.

Serious or Rare Side Effects

  • Severe allergic reaction (angioedema, anaphylaxis).
  • Significant increase in intra‑ocular pressure.
  • Corneal ulcer or keratitis.
  • Vision loss or sudden visual disturbances.
  • Systemic beta‑blocker effects such as bradycardia, hypotension, or bronchospasm.
  • Persistent eye pain or photophobia.

Precautions & Warnings

Before using Latanoprost/Timolol Olikla, consider the following precautions.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Asthma or COPD: avoid due to possible bronchoconstriction from timolol.
  • Cardiac disease: monitor heart rate and blood pressure closely.
  • Severe ocular surface disease: use with caution as irritation may worsen.
  • Contact lens wearers: remove lenses before instillation and wait before reinserting.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Latanoprost/Timolol Olikla may interact with other medications.

Major Interactions (Avoid)

  • Other ocular beta‑blockers (additive systemic beta‑blockade).
  • Systemic non‑selective beta‑blockers (risk of bradycardia, hypotension).
  • Concurrent prostaglandin analogs (increased risk of ocular side effects).

Moderate Interactions (Monitor Closely)

  • Antihistamine eye drops (potential for reduced efficacy).
  • Topical NSAIDs (may increase ocular irritation).
  • Alpha‑adrenergic agonists (possible antagonistic effect on pressure reduction).
  • Carbonic anhydrase inhibitors (monitor intra‑ocular pressure for additive effect).

Frequently Asked Questions

Latanoprost/Timolol Olikla is a prescription eye‑drop formulation used to lower intra‑ocular pressure in patients with open‑angle glaucoma and ocular hypertension, helping to prevent optic nerve damage and preserve vision.

The drug combines two mechanisms: latanoprost, a prostaglandin analog, increases fluid outflow through the uveoscleral pathway, while timolol, a non‑selective beta‑blocker, reduces aqueous humor production. Together they provide a greater pressure‑lowering effect than either agent alone.

The dosing regimen for Latanoprost/Timolol Olikla is determined by the prescribing ophthalmologist. Typically, one drop is instilled in the affected eye(s) once daily, but the exact dose and frequency should follow the individual prescriber's instructions.

Safety data for use during pregnancy or lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting treatment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with monotherapy, the fixed‑dose combination offers superior intra‑ocular pressure reduction and simplifies dosing. It may be preferred over separate agents when patients need both increased outflow and decreased production, reducing the number of daily eye‑drops and improving adherence.

Latanoprost/Timolol Olikla should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and avoid freezing. Do not use if the solution appears discolored or contains particles.

The medication is applied as an ocular solution. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a pocket, and instill one drop into the conjunctival sac of the prescribed eye(s). Close the eye gently for a few seconds and avoid blinking excessively.

Serious risks include severe allergic reactions (e.g., angioedema), significant increase in intra‑ocular pressure, corneal ulceration, vision loss, and systemic beta‑blocker effects such as bradycardia, hypotension, or bronchospasm, especially in patients with underlying cardiac or respiratory conditions.

Patients with known hypersensitivity to timolol, latanoprost, or any component of the formulation should avoid use. Those with severe asthma, chronic obstructive pulmonary disease, bradycardia, heart block, or uncontrolled heart failure should not use this product without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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