Product image of Latanoprost/Timolol Stada (Latanoprost, Timolol) supplied by GNH India

Latanoprost/Timolol Stada

Active Ingredient:
Latanoprost, Timolol
Origin:
EU

Latanoprost/Timolol Stada (Latanoprost, Timolol)

Latanoprost, the active ingredient in Latanoprost/Timolol Stada, is a prostaglandin analog and non‑selective beta‑blocker presented as an ophthalmic solution for ocular use. It is indicated for the management of primary open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanoprost/Timolol Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

Latanoprost/Timolol is used in the treatment of glaucoma and ocular hypertension, conditions characterized by elevated intraocular pressure.

  • Primary open‑angle glaucoma: reduces intraocular pressure to slow optic nerve damage.
  • Ocular hypertension: lowers eye pressure to prevent progression to glaucoma.
  • Secondary glaucoma (e.g., pseudoexfoliative): helps control pressure when monotherapy is insufficient.

How It Works

  • Latanoprost increases uveoscleral outflow of aqueous humor by remodeling the extracellular matrix in the ciliary body, while timolol, a non‑selective β‑adrenergic antagonist, decreases aqueous humor production by blocking β‑receptors in the ciliary epithelium. The combined actions result in a net reduction of intraocular pressure, providing complementary pressure‑lowering effects.

Side Effects

The ocular combination may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Eye irritation: transient burning or stinging after instillation.
  • Conjunctival hyperemia: mild redness of the eye.
  • Eyelash changes: increased length or darkness.
  • Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Persistent ocular inflammation: uveitis or keratitis.
  • Systemic bradycardia: unusually slow heart rate.

Precautions & Warnings

Before prescribing Latanoprost/Timolol, clinicians should consider several safety and handling precautions.

  • Cardiovascular disease: avoid in patients with severe bradycardia or heart block.
  • Respiratory conditions: use cautiously in asthma or chronic obstructive pulmonary disease.
  • Pregnancy and lactation: safety not established; prescribe only if benefit outweighs risk.
  • Contact lens wearers: discontinue lenses before instillation and wait several minutes before reinserting.
  • Drug interactions: review concomitant β‑blockers or other intraocular pressure‑lowering agents.
  • Store at room temperature: keep below 25 °C, protect from light and moisture in the original container.

Avoid Interactions

Latanoprost/Timolol may interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Systemic β‑blockers: additive bradycardia or hypotension.
  • Calcium channel blockers: increased risk of heart block.
  • Anticholinergic eye drops: reduced timolol effect.

Moderate Interactions (Monitor Closely)

  • MAO inhibitors: possible enhanced ocular hypotensive effect.
  • Other prostaglandin analogs: risk of excessive ocular inflammation.
  • NSAID eye drops: may increase irritation.

Frequently Asked Questions

Latanoprost/Timolol Stada is a prescription ophthalmic solution indicated for lowering intraocular pressure in adults with primary open‑angle glaucoma or ocular hypertension. By reducing pressure, it helps prevent optic nerve damage and visual field loss associated with these conditions.

The combination contains two agents: latanoprost, a prostaglandin analog that remodels extracellular matrix to increase uveoscleral outflow of aqueous humor, and timolol, a non‑selective beta‑blocker that reduces aqueous humor production by blocking β‑adrenergic receptors in the ciliary body. Together they produce a greater pressure‑lowering effect than either component alone.

The specific dosing regimen is determined by the prescribing eye‑care professional. Typically, one drop is instilled in each affected eye once daily, but the exact frequency and duration are individualized based on the patient’s response and clinical judgment.

Safety data for Latanoprost/Timolol in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Latanoprost alone primarily increases aqueous outflow, while the addition of timolol also reduces aqueous production. Clinical experience shows that the combination can achieve a greater and more consistent reduction in intraocular pressure, which may be advantageous for patients who need additional pressure control beyond what a single agent provides.

Store the ophthalmic solution at room temperature, below 25 °C, in the original container. Protect it from light and moisture, and keep the bottle tightly closed when not in use. Do not freeze the product.

The medication is applied as an eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid to form a pocket, and place one drop into the conjunctival sac. Close the eye gently for a few seconds and avoid blinking excessively. Do not touch the tip of the bottle to the eye or any surface.

Serious adverse events, although rare, include severe allergic reactions (such as swelling, rash, or breathing difficulty), persistent ocular inflammation (uveitis or keratitis), and systemic bradycardia or heart block, especially in patients with pre‑existing cardiac conditions. Any sudden vision changes, eye pain, or systemic symptoms should prompt immediate medical evaluation.

Patients with known hypersensitivity to latanoprost, timolol, or any excipients in the formulation should avoid the product. It is also contraindicated in individuals with severe bradycardia, second‑ or third‑degree heart block, uncontrolled asthma, or chronic obstructive pulmonary disease without careful medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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