Product image of Latanoprost + Timolol Strandhaven (Timolol Maleate, Latanoprost) supplied by GNH India

Latanoprost + Timolol Strandhaven

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latanoprost + Timolol Strandhaven (Timolol Maleate, Latanoprost)

Timolol maleate, the active ingredient in Latanoprost + Timolol Strandhaven, is a beta‑adrenergic antagonist presented as an ophthalmic solution for ocular use. It, together with latanoprost, treats open‑angle glaucoma and ocular hypertension.
GNH India supplies Latanoprost + Timolol Strandhaven as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Strandhaven Limited T/A Somex Pharma

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Indications & Clinical Uses

Latanoprost + Timolol Strandhaven is used in the management of ocular conditions characterized by elevated intra‑ocular pressure.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers intra‑ocular pressure to prevent conversion to glaucoma.
  • Secondary glaucoma (e.g., pseudoexfoliative): helps control pressure when monotherapy is insufficient.

How It Works

  • Timolol maleate non‑selectively blocks β1 and β2 adrenergic receptors in the ciliary body, decreasing aqueous humor production. Latanoprost, a prostaglandin F2α analog, binds FP receptors in the iris‑ciliary body, enhancing uveoscleral outflow of aqueous humor. The combined actions result in a net reduction of intra‑ocular pressure, providing an additive pressure‑lowering effect.

Side Effects

Adverse reactions to the combination ophthalmic solution may involve the ocular surface or systemic effects.

Common Side Effects

  • Eye irritation: transient burning or stinging after instillation.
  • Redness: conjunctival hyperemia.
  • Blurred vision: temporary visual disturbance.
  • Eyelash changes: increased length or darkness.
  • Darkening of iris: gradual increase in brown pigmentation.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, itching, or rash requiring medical attention.
  • Persistent eye pain: may indicate corneal involvement.
  • Rapid heart rate: systemic β‑blocker effect.
  • Low blood pressure: systemic hypotension.
  • Worsening of asthma: bronchospasm in susceptible individuals.

Precautions & Warnings

Before prescribing Latanoprost + Timolol Strandhaven, clinicians should consider the following precautions.

  • Assess cardiovascular status: avoid in patients with bradycardia or heart block.
  • Evaluate respiratory history: contraindicated in patients with severe asthma or COPD.
  • Monitor intra‑ocular pressure: check response after initiation.
  • Caution in patients with sulfonamide allergy: latanoprost contains a preservative that may trigger reaction.
  • Avoid contact lens wear: may absorb the solution and cause discomfort.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost + Timolol Strandhaven may interact with other medications, affecting efficacy or safety.

Major Interactions (Avoid)

  • Non‑selective β‑blockers (e.g., propranolol): additive systemic β‑blockade may cause bradycardia or hypotension.
  • MAO inhibitors: may potentiate ocular hypotensive effect.
  • Anticholinergic eye drops: may reduce aqueous outflow enhancement.

Moderate Interactions (Monitor Closely)

  • Systemic β‑blockers (e.g., metoprolol): monitor heart rate and blood pressure.
  • Carbonic anhydrase inhibitors (e.g., acetazolamide): increased risk of excessive IOP reduction.
  • Nasal decongestants (e.g., phenylephrine): may counteract ocular pressure lowering.
  • Antifungal eye drops containing preservatives: risk of additive irritation.

Frequently Asked Questions

Latanoprost + Timolol Strandhaven is a prescription ophthalmic solution indicated for the reduction of intra‑ocular pressure in patients with open‑angle glaucoma and ocular hypertension. By lowering pressure, it helps to prevent optic nerve damage and preserve visual function.

Timolol maleate is a non‑selective beta‑adrenergic antagonist that blocks β1 and β2 receptors in the ciliary body, reducing the production of aqueous humor. When combined with latanoprost, which increases outflow, the overall effect is a greater reduction in intra‑ocular pressure.

The prescribed dose is determined by the treating ophthalmologist. Typically, one drop is instilled in each affected eye once daily, but the exact regimen, timing, and duration should follow the clinician’s instructions and the patient’s response.

Safety data in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Latanoprost alone increases aqueous outflow, while timolol alone reduces production. The fixed‑dose combination offers additive pressure‑lowering effects, often achieving target intra‑ocular pressure with a single daily drop, which can improve adherence compared with using two separate eye drops.

Store the ophthalmic solution at room temperature, preferably below 25 °C. Keep the bottle in its original packaging, protect it from light and moisture, and discard any product that appears discolored or contains particles.

The medication is applied as an eye drop. Gently pull down the lower eyelid to create a small pocket, instill one drop into the conjunctival sac of the prescribed eye(s), and close the eye gently for a few seconds. Avoid touching the tip of the bottle to the eye or any surface.

Serious adverse events include severe allergic reactions (e.g., swelling, rash), bronchospasm or worsening asthma in susceptible individuals, marked bradycardia or hypotension due to systemic beta‑blockade, and persistent eye pain that may signal corneal complications. Immediate medical attention is required if these occur.

The product is contraindicated in patients with severe asthma or chronic obstructive pulmonary disease, those with sinus bradycardia, heart block, or other significant cardiac conduction disorders, and individuals known to be allergic to sulfonamide preservatives present in the formulation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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