Product image of Latanostad Comp (Latanoprost, Timolol) supplied by GNH India

Latanostad Comp

Active Ingredient:
Latanoprost, Timolol
Origin:
EU

Latanostad Comp (Latanoprost, Timolol)

Latanoprost, the active ingredient in Latanostad Comp, is a prostaglandin analog presented as eye drops for ocular use. Together with timolol, a non‑selective beta‑blocker, the combination treats primary open‑angle glaucoma and ocular hypertension by lowering intra‑ocular pressure in adult patients.

GNH India supplies Latanostad Comp as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for ophthalmic treatments across Europe and other regulated markets. Our distribution network ensures timely delivery and compliance with local regulatory requirements.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

  • Latanostad Comp acts on ocular pressure regulation pathways to manage glaucoma‑related conditions.
  • Primary open‑angle glaucoma: reduces intra‑ocular pressure to slow optic nerve damage.
  • Ocular hypertension: lowers eye pressure to prevent progression to glaucoma.
  • Secondary open‑angle glaucoma: helps control pressure when other causes are present.

How It Works

  • Latanoprost binds to FP receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor, while timolol blocks β‑adrenergic receptors in the ciliary epithelium, decreasing aqueous humor production. The combined actions result in a net reduction of intra‑ocular pressure.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation
  • Transient blurred vision after instillation
  • Redness of the conjunctiva
  • Increased eyelash growth or darkening
  • Dry eye sensation
  • Mild itching or foreign‑body feeling

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angioedema)
  • Uveitis or iritis
  • Persistent eye pain or photophobia
  • Sudden loss of vision
  • Systemic bradycardia or hypotension
  • Bronchospasm in susceptible individuals

Precautions & Warnings

Before initiating therapy, assess baseline intra‑ocular pressure and ocular health.

  • Hypersensitivity: avoid if patient has known allergy to prostaglandin analogues or beta‑blockers.
  • Iris pigmentation: monitor for possible darkening of iris color.
  • Respiratory conditions: use with caution in asthma or COPD patients.
  • Cardiovascular status: evaluate for bradycardia or heart block before use.
  • Store at room temperature: keep in original container, protect from light and moisture, and discard after the indicated period once opened.

Avoid Interactions

Major Interactions (Avoid)

  • Systemic beta‑blockers: may increase risk of bradycardia or hypotension.
  • Non‑selective beta‑blocker eye drops: additive ocular beta‑blockade effects.

Moderate Interactions (Monitor Closely)

  • Anticholinergic eye drops: may affect pupil size and intra‑ocular pressure.
  • Other prostaglandin analogues: concurrent use can increase ocular irritation.
  • CYP2D6 inhibitors: may modestly raise timolol plasma levels.
  • Sympathomimetic agents: could counteract timolol's ocular effects.

Frequently Asked Questions

Latanostad Comp is a combination eye drop containing latanoprost and timolol, prescribed to lower intra‑ocular pressure in patients with primary open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision. The prescriber determines suitability based on diagnosis.

Latanoprost is a prostaglandin F2α analogue that binds to FP receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor, thereby decreasing intra‑ocular pressure. This mechanism complements timolol's effect on aqueous production.

The dosing regimen is established by the treating ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact frequency and duration are individualized. Patients should follow the prescriber’s instructions.

Safety data for the combination in pregnancy or lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the prescriber should evaluate each case. Breastfeeding mothers should consult their doctor.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The team then provides pricing, availability, shipping details and necessary import documentation.

Compared with monotherapy agents, the latanoprost/timolol combination offers dual mechanisms—enhanced outflow and reduced production—providing greater intra‑ocular pressure reduction in a single formulation. This can improve adherence versus using separate drops, though individual response varies.

Store the eye‑drop bottles at room temperature, below 25 °C, in the original packaging. Protect from light and moisture, and keep the cap tightly closed. Do not freeze. Once opened, discard any remaining solution after the period indicated by the manufacturer.

The medication is applied topically to the eye. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a pocket, and place one drop into the conjunctival sac without touching the bottle tip to the eye or lashes. Close the eye gently and avoid blinking excessively.

Although rare, serious adverse events may include severe allergic reactions, uveitis, persistent eye pain, sudden loss of vision, or systemic effects such as bradycardia and bronchospasm. Patients should seek immediate medical attention if they experience these symptoms.

Individuals with known hypersensitivity to latanoprost, timolol, prostaglandin analogues or beta‑blockers should avoid the product. It is also contraindicated in patients with active ocular infections, severe asthma, chronic obstructive pulmonary disease, or sinus bradycardia without physician supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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