Product image of Latanostill (Latanoprost) supplied by GNH India

Latanostill

Active Ingredient:
Latanoprost
Origin:
EU

Latanostill (Latanoprost)

Latanoprost, the active ingredient in Latanostill, is a Prostaglandin F2α analog presented as eye drops for ocular use. It lowers intra‑ocular pressure and is employed in the management of open‑angle glaucoma and ocular hypertension in adult patients who require long‑term IOP control.

GNH India supplies Latanostill as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Clients benefit from comprehensive regulatory support and timely delivery across multiple regions.

Manufacturer / TM Owner

Bruschettini S.R.L

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Indications & Clinical Uses

  • Latanostill (latanoprost) reduces intra‑ocular pressure by enhancing aqueous humor outflow, and is indicated for the following ocular conditions:
  • Open‑angle glaucoma: lowers intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: reduces elevated eye pressure to prevent development of glaucoma.
  • Pseudoexfoliative glaucoma: decreases intra‑ocular pressure in this secondary open‑angle glaucoma subtype.

How It Works

  • Latanoprost is a prostaglandin F2α analog that binds to FP receptors in the ciliary muscle, activating the phosphatidylinositol‑calcium signaling cascade. This leads to remodeling of the extracellular matrix and relaxation of the ciliary muscle, thereby increasing uveoscleral outflow of aqueous humor and consequently lowering intra‑ocular pressure. The effect is sustained for 24‑48 hours after a single instillation, allowing once‑daily dosing.

Side Effects

Latanostill may cause ocular and systemic adverse reactions; the most frequently reported are listed below.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Eye itching: transient pruritus.
  • Increased iris pigmentation: gradual darkening of the iris color.
  • Eyelash changes: growth and darkening of eyelashes.

Serious or Rare Side Effects

  • Severe eye inflammation: uveitis or iritis requiring medical attention.
  • Allergic reaction: swelling, rash, or severe irritation of the eye.
  • Vision loss: sudden decrease in visual acuity.

Precautions & Warnings

  • Before using Latanostill, consider the following precautions to ensure safe and effective therapy.
  • Monitor intra‑ocular pressure: regular eye‑pressure checks are required.
  • Avoid contact lenses: do not wear soft lenses for at least 15 minutes after instillation.
  • Inform surgeon: disclose use before any ocular surgery.
  • Do not use in active eye infection: postpone treatment until resolved.
  • Discontinue if severe side effects occur: seek ophthalmologic evaluation.
  • Store at room temperature: keep bottle tightly closed, protect from light, and store in original container.

Avoid Interactions

Latanostill can interact with other ocular or systemic agents; the following interactions are noteworthy.

Major Interactions (Avoid)

  • Concurrent use with other prostaglandin analogs: may increase risk of ocular side effects.
  • Use with ocular corticosteroids: can reduce steroid efficacy and increase inflammation risk.

Moderate Interactions (Monitor Closely)

  • Combination with beta‑blocker eye drops: additive intra‑ocular pressure lowering effect, monitor pressure.
  • Use with carbonic anhydrase inhibitor eye drops: may enhance pressure reduction, adjust dosing if needed.
  • Systemic NSAIDs: may modestly affect prostaglandin pathways, observe for changes.

Frequently Asked Questions

Latanostill contains latanoprost, a prostaglandin analog indicated for reducing intra‑ocular pressure in patients with open‑angle glaucoma and ocular hypertension. By increasing outflow of aqueous humor, it helps prevent optic nerve damage and visual field loss associated with elevated eye pressure.

Latanoprost binds to FP receptors in the ciliary body, activating a signaling cascade that remodels extracellular matrix and relaxes the ciliary muscle. This enhances uveoscleral outflow of aqueous humor, leading to a sustained reduction in intra‑ocular pressure after each daily dose.

The dosage of Latanostill is determined by a qualified eye‑care professional. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but the prescriber may adjust the regimen based on individual response and tolerance.

Safety data for latanoprost during pregnancy and lactation are limited. It is classified as pregnancy category unknown, and use is generally avoided unless the potential benefit outweighs the risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To request Latanostill, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Latanostill (latanoprost) is a prostaglandin analog, often preferred for its once‑daily dosing and strong intra‑ocular pressure‑lowering effect. Compared with beta‑blocker eye drops, it typically offers greater pressure reduction with fewer systemic side effects, though individual response may vary.

Latanostill eye‑drop bottles should be stored at room temperature, below 25 °C, in the original packaging. Keep the bottle tightly closed, protect it from light, and avoid freezing. Do not refrigerate unless otherwise directed by the manufacturer.

Latanostill is applied as a sterile ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill one drop into each prescribed eye. Avoid touching the tip of the bottle to the eye or any surface to maintain sterility.

The most serious adverse events include severe eye inflammation such as uveitis or iritis, allergic reactions that may cause swelling or rash, and sudden vision loss. If any of these occur, the patient should discontinue use immediately and seek urgent ophthalmologic care.

Latanostill should not be used by individuals with known hypersensitivity to latanoprost or any component of the formulation, and it is contraindicated in eyes with active infection or inflammation. Caution is also advised for patients who have had recent ocular surgery until cleared by their surgeon.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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