Product image of Latanotim-Vision Sine (Timolol Maleate, Latanoprost) supplied by GNH India

Latanotim-Vision Sine

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latanotim-Vision Sine (Timolol Maleate, Latanoprost)

Timolol maleate and latanoprost, the active ingredient in Latanotim-Vision Sine, is a beta‑blocker and prostaglandin analog combination presented as an ophthalmic solution for ocular use. It treats open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Latanotim-Vision Sine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for ophthalmic medications across global markets. Clients benefit from consistent batch release, regulatory compliance, and dedicated technical support throughout the procurement process.

Manufacturer / TM Owner

Omnivision Gmbh

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Indications & Clinical Uses

  • Latanotim-Vision Sine, a combination beta‑blocker and prostaglandin analog eye drop, is used to manage conditions that involve elevated intraocular pressure.
  • Open-angle glaucoma: reduces intraocular pressure to prevent optic nerve damage
  • Ocular hypertension: lowers eye pressure to decrease the risk of developing glaucoma
  • Elevated intraocular pressure: improves aqueous outflow and decreases production to maintain normal pressure

How It Works

  • Timolol maleate acts as a non‑selective beta‑adrenergic antagonist, decreasing aqueous humor production by blocking β1 and β2 receptors in the ciliary body. Latanoprost is a prostaglandin F2α analog that binds to FP receptors, enhancing uveoscleral outflow of aqueous humor. This dual mechanism provides complementary pressure‑lowering effects, allowing once‑daily dosing and improving patient adherence.

Side Effects

Latanotim-Vision Sine may cause ocular and systemic adverse reactions.

Common Side Effects

  • Eye irritation: transient burning or stinging after instillation
  • Blurred vision: temporary visual disturbance
  • Increased eyelash growth: longer, thicker lashes
  • Conjunctival hyperemia: mild redness of the eye

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing
  • Significant drop in heart rate or blood pressure: bradycardia or hypotension
  • Bronchospasm: wheezing or difficulty breathing in asthmatic patients

Precautions & Warnings

  • Before using Latanotim-Vision Sine, consider the following precautions to ensure safe therapy.
  • Pregnancy: consult a healthcare professional before use
  • Breastfeeding: discuss potential risks with a physician
  • Respiratory disease: avoid in patients with asthma or COPD due to beta‑blocker effects
  • Cardiovascular conditions: monitor heart rate and blood pressure in patients with bradycardia or heart block
  • Drug interactions: review concomitant medications for beta‑blocker or prostaglandin interactions
  • Store at room temperature: keep the bottle tightly closed, protect from light and moisture

Avoid Interactions

Latanotim-Vision Sine can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Systemic beta‑blockers: additive cardiovascular depression
  • Bronchodilators (beta‑agonists): reduced bronchodilatory effect
  • Other ocular beta‑blockers: increased systemic absorption and beta‑blockade

Moderate Interactions (Monitor Closely)

  • Carbonic anhydrase inhibitors: enhanced intraocular pressure reduction
  • Topical prostaglandin analogs: potential additive ocular effects
  • Systemic steroids: may diminish prostaglandin efficacy

Frequently Asked Questions

Latanotim-Vision Sine is an ophthalmic solution that combines timolol maleate and latanoprost to lower intraocular pressure. It is prescribed for patients with open‑angle glaucoma or ocular hypertension to help prevent optic nerve damage and preserve visual function.

Timolol maleate blocks beta‑adrenergic receptors in the eye, reducing the production of aqueous humor. Latanoprost mimics prostaglandin F2α, binding to FP receptors and increasing uveoscleral outflow of fluid. Together they provide a complementary mechanism that lowers eye pressure effectively.

The dosing regimen for Latanotim-Vision Sine is determined by the prescribing clinician based on the individual’s condition and response. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule should follow the healthcare provider’s instructions.

Safety data for timolol maleate and latanoprost during pregnancy or lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant. Patients should discuss their situation with a qualified healthcare professional.

To request Latanotim-Vision Sine, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with monotherapy options, the timolol‑latanoprost combination offers dual pressure‑lowering mechanisms in a single drop, often achieving greater IOP reduction than either agent alone. This can simplify treatment regimens and improve adherence, while maintaining a safety profile similar to the individual components.

Latanotim-Vision Sine should be stored at room temperature, protected from light and moisture. Keep the bottle tightly closed when not in use. Do not freeze the product, and discard any solution that appears discolored or contains particles.

The medication is applied as an eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid to form a pocket, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.

Serious adverse events include severe allergic reactions such as swelling or difficulty breathing, marked bradycardia or hypotension, and bronchospasm in patients with asthma or COPD. Any sudden visual changes, eye pain, or systemic symptoms should prompt immediate medical evaluation.

Patients with known hypersensitivity to timolol, latanoprost, or any component of the formulation should avoid the product. Individuals with severe sinus node dysfunction, uncontrolled asthma, or certain cardiac conduction disorders should not use it without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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