Product image of Latatim (Timolol Maleate, Latanoprost) supplied by GNH India

Latatim

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Latatim (Timolol Maleate, Latanoprost)

Timolol maleate and latanoprost, the active ingredients in Latatim, are a beta blocker and a prostaglandin analog presented as eye drops for ocular use. They are prescribed to lower intraocular pressure in glaucoma and ocular hypertension patients.

GNH India supplies Latatim as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sifi S.P.A.

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Indications & Clinical Uses

  • Latatim is used in the management of ocular conditions that require reduction of intraocular pressure.
  • Open-angle glaucoma: lowers pressure to protect the optic nerve.
  • Ocular hypertension: reduces elevated eye pressure to prevent progression to glaucoma.
  • Pseudoexfoliative glaucoma: helps control pressure in this secondary form of glaucoma.

How It Works

  • Timolol maleate non‑selectively blocks beta‑adrenergic receptors in the ciliary body, decreasing aqueous humor production. Latanoprost, a prostaglandin F2α analog, binds to FP receptors, remodeling the extracellular matrix and enhancing uveoscleral outflow. The combined actions result in a synergistic reduction of intraocular pressure.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation.
  • Transient blurred vision after instillation.
  • Redness of the conjunctiva.
  • Dry eye or foreign‑body feeling.

Serious or Rare Side Effects

  • Severe allergic reaction with swelling of the eyelid.
  • Worsening of glaucoma if pressure drops excessively.
  • Systemic beta‑blocker effects such as bradycardia or chest discomfort.

Precautions & Warnings

  • Before using Latatim, consider the following precautions.
  • Monitor intraocular pressure: schedule regular eye examinations.
  • Assess cardiovascular status: caution in patients with bradycardia or heart block.
  • Avoid use in asthma: beta‑blocker component may trigger bronchospasm.
  • Do not combine with other prostaglandin analogs: risk of additive ocular effects.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latatim may interact with other medications; review the following.

Major Interactions (Avoid)

  • Systemic non‑selective beta‑blockers: risk of additive cardiac depression.
  • Carbonic anhydrase inhibitors: may cause excessive hypotension.
  • Other ocular hypotensive agents: potential for over‑lowering eye pressure.

Moderate Interactions (Monitor Closely)

  • Topical anesthetics: may increase ocular absorption of the drug.
  • Anticholinergic eye drops: could affect pupil dynamics.
  • Systemic antihypertensives: monitor blood pressure for additive effects.

Frequently Asked Questions

Latatim is a prescription eye‑drop combination of timolol maleate and latanoprost used to lower intraocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Timolol maleate blocks beta‑adrenergic receptors in the eye, reducing aqueous humor production. Latanoprost activates prostaglandin F2α receptors, increasing uveoscleral outflow of fluid. Together they provide a complementary reduction of intraocular pressure.

The dosing regimen for Latatim is determined by the prescribing ophthalmologist. Typically, one drop is instilled in the affected eye(s) once daily, but the exact frequency and quantity are individualized based on patient response and clinical judgment.

Safety data for Latatim in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To request Latatim, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latatim combines a beta‑blocker and a prostaglandin analog, offering dual mechanisms in a single bottle. Compared with monotherapy agents, it can achieve greater pressure reduction, potentially simplifying treatment regimens and improving adherence versus using separate drops.

Latatim eye drops should be stored at room temperature, below 25 °C, in the original packaging. Protect the bottle from direct sunlight and moisture, and keep the cap tightly closed when not in use.

Latatim is applied as an ocular solution. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac of each prescribed eye, avoiding contact between the tip and the eye or any surface.

Serious risks include severe allergic reactions affecting the eyelid or surrounding tissue, systemic beta‑blocker effects such as bradycardia or hypotension, and excessive lowering of intraocular pressure that could compromise ocular perfusion.

Latatim is contraindicated in patients with known hypersensitivity to timolol, latanoprost or any excipients, in individuals with severe asthma, certain cardiac conduction disorders, and in eyes with active intraocular inflammation or infection.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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