Product image of Laticort (Hydrocortisone Butyrate) supplied by GNH India

Laticort

Active Ingredient:
Hydrocortisone Butyrate
Origin:
EU

Laticort (Hydrocortisone Butyrate)

Hydrocortisone butyrate, the active ingredient in Laticort, is a corticosteroid presented as a topical formulation for skin application. It is used to reduce inflammation and relieve symptoms in various dermatologic conditions such as eczema, psoriasis and contact dermatitis, primarily in adult and pediatric patients as directed by a healthcare professional.

GNH India supplies Laticort as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch Health Ireland Limited

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Indications & Clinical Uses

Laticort, a topical corticosteroid, is employed to manage inflammatory skin disorders. It helps control symptoms and improve skin condition in the following indications:

  • Atopic dermatitis: reduces itching, redness and swelling, facilitating skin healing.
  • Contact dermatitis: alleviates inflammatory response caused by irritants or allergens.
  • Psoriasis: diminishes plaque formation and scaling by suppressing excessive skin cell proliferation.

How It Works

  • Hydrocortisone butyrate penetrates the epidermis and binds to intracellular glucocorticoid receptors. This complex translocates to the nucleus, where it modulates gene transcription, leading to decreased production of pro‑inflammatory cytokines, inhibition of leukocyte migration, and suppression of immune responses, thereby reducing skin inflammation and edema.

Side Effects

Topical application of Laticort may be associated with local and systemic adverse reactions.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Pruritus or mild itching.
  • Dryness or flaking of the skin.
  • Erythema or mild redness.
  • Folliculitis or small pustules.
  • Skin irritation or contact dermatitis.

Serious or Rare Side Effects

  • Skin atrophy or thinning with prolonged use.
  • Telangiectasia (visible small blood vessels).
  • Secondary bacterial, fungal or viral infection.
  • Allergic contact dermatitis to the formulation.
  • Systemic absorption leading to hypothalamic‑pituitary‑adrenal axis suppression.
  • Hypertrichosis (excessive hair growth) in the treated area.

Precautions & Warnings

Before prescribing Laticort, clinicians should consider several safety measures.

  • Assess severity: Use only for moderate to severe inflammatory dermatoses where benefits outweigh risks.
  • Limit duration: Avoid continuous use beyond recommended periods to reduce skin atrophy.
  • Occlusion: Do not apply under airtight dressings unless specifically instructed.
  • Infected skin: Do not use on bacterial, fungal or viral skin infections without appropriate antimicrobial therapy.
  • Sensitive areas: Avoid routine use on the face, intertriginous zones or mucous membranes unless directed.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Laticort may interact with other medications or therapies applied to the skin.

Major Interactions (Avoid)

  • Concurrent systemic corticosteroids: may increase systemic glucocorticoid exposure.
  • Potent CYP3A4 inhibitors applied topically: could raise local drug concentration.
  • Other potent topical steroids: risk of additive skin thinning.

Moderate Interactions (Monitor Closely)

  • Topical antibiotics: may mask signs of infection.
  • Alcohol‑based skin products: can enhance irritation.
  • Phototherapy: may increase photosensitivity of treated skin.
  • Antifungal creams: potential for reduced efficacy of either agent.
  • Immunosuppressants: monitor for heightened infection risk.

Frequently Asked Questions

Laticort contains hydrocortisone butyrate, a topical corticosteroid indicated for inflammatory skin disorders such as atopic dermatitis, contact dermatitis and psoriasis. It helps reduce redness, swelling, itching and scaling associated with these conditions when applied as prescribed by a healthcare professional.

Hydrocortisone butyrate penetrates the epidermis and binds to intracellular glucocorticoid receptors. The resulting complex alters gene transcription, decreasing the production of inflammatory cytokines and chemokines, inhibiting leukocyte migration, and suppressing immune activity, which collectively reduces skin inflammation and edema.

The specific dosage and frequency of Laticort are determined by the prescribing clinician based on the severity of the skin condition, the patient’s age, and the treatment area. Patients should follow the prescriber’s instructions and not alter the regimen without medical advice.

Safety data for hydrocortisone butyrate in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the prescribing physician after evaluating the individual situation.

To request Laticort, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hydrocortisone butyrate is a medium‑potency corticosteroid, offering a balance between efficacy and safety. Compared with low‑potency agents (e.g., hydrocortisone 1%), it provides stronger anti‑inflammatory action, while being less potent than high‑potency steroids such as clobetasol, which carry a higher risk of skin atrophy with prolonged use.

Laticort should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and ensure it is out of reach of children.

Laticort is applied topically to the affected skin area in a thin layer, usually once or twice daily as directed by the prescriber. The skin should be clean and dry before application, and hands should be washed after use to avoid inadvertent spread.

Serious risks include skin atrophy, telangiectasia, secondary infections, allergic reactions, and systemic effects such as hypothalamic‑pituitary‑adrenal axis suppression when used over large areas or for prolonged periods. Patients should report any unusual skin changes or systemic symptoms to their healthcare provider promptly.

Laticort is contraindicated in individuals with known hypersensitivity to hydrocortisone butyrate or any formulation excipients. It should also be avoided on untreated bacterial, fungal, viral, or tuberculous skin infections, and in patients with systemic corticosteroid dependence without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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