Product image of Laticort (Hydrocortisone Butyrate) supplied by GNH India

Laticort

Active Ingredient:
Hydrocortisone Butyrate
Origin:
EU

Laticort (Hydrocortisone Butyrate)

Hydrocortisone Butyrate, the active ingredient in Laticort, is a potent corticosteroid presented as a topical cream for cutaneous application. It exerts anti‑inflammatory and immunosuppressive actions, helping to control symptoms of inflammatory skin disorders such as eczema, psoriasis, and allergic dermatitis in adult and pediatric patients.

GNH India supplies Laticort as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, ensuring quality compliance with EU standards, reliable global logistics, and dedicated technical support. The product is manufactured under strict GMP conditions to meet the expectations of healthcare providers across continents.

Manufacturer / TM Owner

Bausch Health Ireland Limited

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Indications & Clinical Uses

Laticort (hydrocortisone butyrate) is used to treat inflammatory skin conditions by reducing local inflammation and immune activity.

  • Eczema: alleviates redness, itching and swelling.
  • Psoriasis: reduces plaque formation and scaling.
  • Allergic dermatitis: diminishes rash and edema.
  • Atopic dermatitis: improves barrier function and symptom control.

How It Works

  • Hydrocortisone butyrate binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This leads to inhibition of pro‑inflammatory cytokine production, suppression of leukocyte migration, and reduced expression of adhesion molecules, thereby delivering potent anti‑inflammatory and immunosuppressive effects in the skin.

Side Effects

Topical hydrocortisone butyrate may cause a range of local and systemic reactions.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Pruritus (itching).
  • Skin dryness or flaking.
  • Folliculitis.
  • Acneiform eruption.
  • Mild erythema.

Serious or Rare Side Effects

  • Skin atrophy or thinning.
  • Telangiectasia (visible small blood vessels).
  • Hypopigmentation or depigmentation.
  • Systemic absorption leading to adrenal suppression.
  • Allergic contact dermatitis.
  • Secondary bacterial, fungal or viral skin infection.

Precautions & Warnings

When using Laticort, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Long‑term use: limit duration to avoid skin atrophy.
  • Large surface area: avoid extensive application to reduce systemic exposure.
  • Children: use the lowest effective potency and monitor closely.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Hydrocortisone butyrate may interact with certain systemic or topical agents.

Major Interactions (Avoid)

  • Concomitant systemic corticosteroids: increased risk of systemic side effects.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole): may raise local steroid levels.
  • Live vaccines: reduced efficacy when applied to large areas.

Moderate Interactions (Monitor Closely)

  • Topical antibiotics or antifungals: may alter skin flora and affect healing.
  • NSAID creams: potential for increased local irritation.
  • Occlusive dressings: enhance absorption, requiring dose adjustment.

Frequently Asked Questions

Laticort contains hydrocortisone butyrate, a topical corticosteroid used to treat inflammatory skin conditions such as eczema, psoriasis, allergic and atopic dermatitis by reducing redness, itching, and swelling.

Hydrocortisone butyrate binds to glucocorticoid receptors in skin cells, altering gene transcription to suppress pro‑inflammatory cytokines, inhibit leukocyte migration, and reduce vascular permeability, resulting in anti‑inflammatory and immunosuppressive effects.

The appropriate amount and frequency of Laticort are determined by the prescribing healthcare professional based on the specific condition, severity, patient age, and treatment area. Patients should follow the prescriber’s instructions exactly.

Safety in pregnancy and lactation has not been definitively established. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Laticort.

To request Laticort, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Hydrocortisone butyrate is a mid‑potency corticosteroid, offering stronger anti‑inflammatory action than low‑potency agents like hydrocortisone 1% but less potency than very strong steroids such as clobetasol propionate. Choice depends on disease severity, body area treated, and duration of therapy.

Store Laticort at room temperature, away from excess heat and moisture. Keep the tube or container tightly closed in its original packaging, and protect it from direct sunlight to maintain product stability.

Laticort is applied topically to the affected skin area in a thin layer, usually once or twice daily as directed by a healthcare professional. The skin should be clean and dry before application, and hands should be washed after use.

Serious risks include skin atrophy, telangiectasia, hypopigmentation, and systemic effects such as adrenal suppression when large areas are treated or used for prolonged periods. Patients should report any unusual skin changes or systemic symptoms to their doctor promptly.

Laticort should be avoided in individuals with known hypersensitivity to hydrocortisone butyrate or any formulation components, in patients with untreated fungal, bacterial, or viral skin infections, and in those where a less potent corticosteroid would be more appropriate.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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