Product image of Latiotim (Latanoprost, Timolol) supplied by GNH India

Latiotim

Active Ingredient:
Latanoprost, Timolol
Origin:
EU

Latiotim (Latanoprost, Timolol)

Latanoprost, the active ingredient in Latiotim, is a prostaglandin analog presented as an eye drop for ocular use. It treats open-angle glaucoma and ocular hypertension by lowering intra‑ocular pressure.
GNH India supplies Latiotim as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz A/S

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Indications & Clinical Uses

  • Latiotim, a combination of a prostaglandin analog and a beta‑blocker, is used to manage conditions that involve elevated intra‑ocular pressure.
  • Open‑angle glaucoma: reduces intra‑ocular pressure to prevent optic‑nerve damage
  • Ocular hypertension: lowers eye pressure to reduce risk of progression to glaucoma
  • Secondary glaucoma (e.g., pseudoexfoliative): assists in pressure reduction when other therapies are insufficient

How It Works

  • Latanoprost binds to prostaglandin F receptors in the ciliary muscle, enhancing uveoscleral outflow of aqueous humor, while timolol blocks β1 and β2 adrenergic receptors in the ciliary epithelium, decreasing aqueous humor production. The combined actions result in a net reduction of intra‑ocular pressure.

Side Effects

Latiotim may cause ocular and systemic reactions.

Common Side Effects

  • Eye irritation or burning sensation
  • Blurred vision shortly after instillation
  • Redness of the conjunctiva
  • Increased eyelash growth

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., swelling, rash)
  • Persistent eye pain or sudden vision loss
  • Systemic beta‑blocker effects such as bradycardia, hypotension or bronchospasm

Precautions & Warnings

  • Before prescribing Latiotim, consider the following precautions.
  • Assess intra‑ocular pressure baseline: ensure appropriate target pressure is set
  • Avoid in patients with asthma or severe chronic obstructive pulmonary disease: timolol may exacerbate bronchospasm
  • Check for known hypersensitivity to prostaglandin analogs or timolol before use
  • Inform patients about possible iris colour change and advise regular eye examinations
  • Store at room temperature: keep in the original container, protect from light and moisture

Avoid Interactions

Latiotim can interact with other medications; review patient medication lists.

Major Interactions (Avoid)

  • Non‑selective beta‑blocker antagonists (e.g., propranolol): additive systemic beta‑blockade
  • Monoamine oxidase inhibitors: may enhance ocular hypotensive effect
  • Other prostaglandin analog eye drops: risk of excessive intra‑ocular pressure lowering

Moderate Interactions (Monitor Closely)

  • Systemic beta‑blockers (e.g., metoprolol): monitor heart rate and blood pressure
  • Anticholinergic eye drops: may reduce efficacy of Latiotim
  • Respiratory bronchodilators: watch for bronchospasm in susceptible patients

Frequently Asked Questions

Latiotim is a prescription eye‑drop containing latanoprost and timolol, indicated for the reduction of intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to prevent optic‑nerve damage and preserve visual field.

Latanoprost, a prostaglandin analog, increases uveoscleral outflow of aqueous humor, while timolol, a non‑selective beta‑adrenergic blocker, decreases aqueous humor production. The combined effect lowers intra‑ocular pressure more effectively than either component alone.

The dosing regimen for Latiotim is determined by the prescribing clinician. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but the exact schedule and number of drops are individualized based on patient response and tolerability.

Safety data for Latiotim during pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with monotherapy agents, the latanoprost/timolol combination offers dual mechanisms—enhanced outflow and reduced production—resulting in greater intra‑ocular pressure reduction. It may be preferred when a single‑agent regimen does not achieve target pressure, though individual response and tolerance vary.

Latiotim eye drops should be stored at room temperature, below 25 °C, in the original container. Protect the bottle from light and moisture, and keep it out of reach of children. Do not freeze the product.

The eye drops are applied topically. After washing hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill one drop into the conjunctival sac of each prescribed eye. Close the eye gently for a few seconds and avoid blinking excessively.

Serious adverse events, although rare, include severe allergic reactions, persistent eye pain, sudden loss of vision, and systemic beta‑blocker effects such as bradycardia, hypotension or bronchospasm. Patients should seek immediate medical attention if any of these occur.

Latiotim is contraindicated in patients with known hypersensitivity to latanoprost, timolol or any component of the formulation, and in individuals with asthma, chronic obstructive pulmonary disease, severe bradycardia, or sinus node dysfunction due to the beta‑blocker component. Consultation with a healthcare professional is required before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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