Product image of Latrovin (Atorvastatin) supplied by GNH India

Latrovin

Active Ingredient:
Atorvastatin
Origin:
EU

Latrovin (Atorvastatin)

Atorvastatin, the active ingredient in Latrovin, is a HMG‑CoA reductase inhibitor (statin) presented as a tablet for oral use. It treats hypercholesterolemia and helps reduce cardiovascular risk in adult patients.

GNH India supplies Latrovin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Naturalia S.A.

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Indications & Clinical Uses

  • Atorvastatin is used to manage disorders of lipid metabolism and to reduce cardiovascular events.
  • Hypercholesterolemia: lowers LDL‑cholesterol and total cholesterol levels.
  • Primary prevention of cardiovascular disease: reduces risk of heart attack and stroke in at‑risk adults.
  • Secondary prevention of cardiovascular disease: helps prevent recurrent events in patients with established disease.
  • Mixed dyslipidemia: improves overall lipid profile by decreasing LDL and triglycerides while modestly raising HDL.

How It Works

  • Atorvastatin competitively inhibits HMG‑CoA reductase, the key enzyme in hepatic cholesterol biosynthesis. This inhibition reduces intracellular cholesterol, leading to up‑regulation of LDL receptors on hepatocyte surfaces, which enhances clearance of circulating LDL particles and lowers plasma cholesterol concentrations.

Side Effects

Common Side Effects

  • Muscle aches or weakness
  • Headache
  • Nausea
  • Abdominal pain
  • Constipation
  • Elevated liver enzymes

Serious or Rare Side Effects

  • Rhabdomyolysis
  • Severe liver injury
  • Allergic reactions such as rash or angioedema
  • Myopathy with marked CK elevation
  • Acute pancreatitis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

  • Before initiating therapy, consider the following precautions.
  • Liver function monitoring: assess baseline hepatic enzymes and repeat periodically.
  • Muscle symptoms monitoring: discontinue if unexplained muscle pain with CK rise occurs.
  • Drug interactions: review concomitant medications that affect statin metabolism.
  • Pregnancy and lactation: avoid use unless benefits outweigh potential risks.
  • Renal impairment: adjust dose in severe renal dysfunction.
  • Store at room temperature: keep below 25 °C, protect from moisture and light.

Avoid Interactions

Atorvastatin may interact with several medicines; categorize as follows.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole): increase atorvastatin levels.
  • Gemfibrozil: heightened risk of myopathy.
  • High‑dose niacin: increased liver toxicity.
  • Cyclosporine: elevated statin concentrations.
  • HIV protease inhibitors: greater risk of rhabdomyolysis.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: may reduce absorption.
  • Warfarin: possible enhancement of anticoagulant effect.
  • Digoxin: potential increase in serum levels.
  • Beta‑blockers: additive lipid‑lowering effect.
  • Grapefruit juice: may modestly raise exposure.

Frequently Asked Questions

Latrovin contains atorvastatin, a statin indicated for lowering elevated cholesterol levels, treating hypercholesterolemia, and reducing the risk of cardiovascular events such as heart attack and stroke in both primary and secondary prevention settings.

Atorvastatin blocks the enzyme HMG‑CoA reductase in the liver, which is essential for cholesterol synthesis. This reduction in hepatic cholesterol prompts the liver to increase LDL‑receptor expression, enhancing removal of LDL cholesterol from the bloodstream and lowering overall plasma cholesterol.

The specific dose of Latrovin is determined by the prescribing clinician based on the patient’s cholesterol levels, cardiovascular risk profile, and tolerance. Dosage adjustments are made individually and should follow the prescriber’s instructions.

Statins, including atorvastatin, are generally contraindicated during pregnancy because of potential fetal harm. Use while breastfeeding is not recommended unless the benefits clearly outweigh the risks, and this decision should be made by a healthcare professional.

To place an order, submit an enquiry on the Latrovin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Atorvastatin is a high‑potency statin that typically provides greater LDL‑cholesterol reduction than lower‑intensity statins such as pravastatin or simvastatin. Compared with non‑statin agents, it has a well‑established evidence base for cardiovascular risk reduction, though individual response and tolerance may vary.

Latrovin tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Do not store in areas of high humidity or extreme heat.

Latrovin is taken orally, usually once daily, with or without food, as directed by the prescribing clinician. Swallow the tablet whole with a glass of water and follow any specific timing instructions provided by the healthcare professional.

The most serious adverse reactions include rhabdomyolysis, a severe muscle breakdown that can lead to kidney failure, and significant liver injury. Patients should report unexplained muscle pain, weakness, dark urine, or signs of liver dysfunction such as jaundice promptly.

Latrovin should be avoided in individuals with active liver disease, unexplained persistent elevations of hepatic enzymes, known hypersensitivity to atorvastatin or any excipients, and in pregnant or nursing women unless a physician determines that the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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