Product image of Lattulosio Abc (Lactulose) supplied by GNH India

Lattulosio Abc

Active Ingredient:
Lactulose
Origin:
EU

Lattulosio Abc (Lactulose)

Lactulose, the active ingredient in Lattulosio Abc, is an osmotic laxative presented as an oral formulation for oral use. It is used to relieve constipation and to reduce ammonia levels in patients with hepatic encephalopathy, primarily in adult populations.

GNH India supplies Lattulosio Abc as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to essential medicines across multiple markets and ensuring compliance with regulatory standards.

Manufacturer / TM Owner

Abc Farmaceutici S.P.A.

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Indications & Clinical Uses

Lactulose is an osmotic laxative used to manage conditions related to bowel motility and ammonia accumulation.

  • Constipation: softens stools and promotes regular bowel movements.
  • Hepatic encephalopathy: lowers colonic ammonia absorption, helping improve mental status.

How It Works

  • Lactulose remains largely unabsorbed in the small intestine and reaches the colon where it increases osmotic pressure, drawing water into the lumen to soften stools. Colonic bacteria metabolize lactulose to short‑chain fatty acids, lowering the colonic pH and converting ammonia to ammonium, which reduces systemic ammonia absorption.

Side Effects

Lactulose may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased intestinal gas.
  • Diarrhea: loose, watery stools.
  • Nausea: sensation of wanting to vomit.
  • Stomach cramps: intermittent abdominal pain.
  • Thirst: increased desire for fluids.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal levels of sodium or potassium.
  • Dehydration: excessive loss of body fluids.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe abdominal pain: persistent, intense pain requiring medical attention.

Precautions & Warnings

Before initiating lactulose therapy, consider the following safety measures.

  • Renal function assessment: monitor patients with impaired kidney function.
  • Electrolyte monitoring: watch for hyponatremia or hypokalemia during treatment.
  • Diabetes caution: observe blood glucose levels as lactulose may affect carbohydrate absorption.
  • Intestinal obstruction avoidance: contraindicated in patients with known bowel blockage.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Lactulose can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing magnesium: may reduce lactulose's osmotic effect.
  • Stimulant laxatives: increase risk of electrolyte disturbances.
  • Diuretics: heighten potential for dehydration.

Moderate Interactions (Monitor Closely)

  • Antibiotics (e.g., rifaximin): may change colonic flora and affect lactulose metabolism.
  • Oral hypoglycemic agents: monitor glucose control as lactulose can influence carbohydrate handling.

Frequently Asked Questions

Lattulosio Abc contains lactulose, which is prescribed to treat constipation by softening stools and to manage hepatic encephalopathy by lowering ammonia levels in the colon. Both indications are based on its osmotic and acidifying actions in the gastrointestinal tract.

Lactulose is a synthetic disaccharide that is not absorbed in the small intestine. It reaches the colon where it draws water into the lumen, softening stool, and is fermented by bacteria into short‑chain fatty acids. This acidifies the colon, converting ammonia to ammonium, which reduces systemic absorption of ammonia.

The appropriate dose of Lattulosio Abc is determined by the prescribing healthcare professional based on the patient’s condition, severity, and response to therapy. Dosage may be adjusted over time, and patients should follow the specific instructions provided by their prescriber.

Safety data for lactulose in pregnancy and lactation are limited. The prescriber will weigh potential benefits against possible risks before recommending use. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss their situation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Lactulose is an osmotic laxative, differing from stimulant laxatives that increase intestinal motility. Its dual action—softening stool and lowering colonic ammonia—makes it uniquely suited for both constipation and hepatic encephalopathy, whereas many other laxatives address only bowel movement frequency.

Lattulosio Abc should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Lattulosio Abc is taken orally, usually as a liquid solution or syrup. It can be measured with a calibrated dosing device and consumed directly or mixed with a small amount of water or juice, as directed by the prescribing clinician.

Serious risks include severe electrolyte imbalance, dehydration, and rare allergic reactions such as rash or difficulty breathing. Patients experiencing persistent diarrhea, extreme weakness, or signs of an allergic response should seek medical attention promptly.

Lactulose is contraindicated in individuals with known intestinal obstruction, perforation, or severe inflammatory bowel disease. Patients with hypersensitivity to lactulose or any component of the formulation should also avoid its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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