Product image of Lattulosio Alter (Lactulose) supplied by GNH India

Lattulosio Alter

Active Ingredient:
Lactulose
Origin:
EU

Lattulosio Alter (Lactulose)

Lactulose, the active ingredient in Lattulosio Alter, is an osmotic laxative presented as an oral formulation for oral use. It is employed to relieve constipation and to reduce ammonia absorption in patients with hepatic encephalopathy.\n\nGNH India supplies Lattulosio Alter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratori Alter S.R.L.

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Indications & Clinical Uses

  • Lattulosio Alter is used in conditions affecting bowel motility and ammonia metabolism.\n\nConstipation: facilitates bowel movements by increasing water content in the intestinal lumen.\nHepatic encephalopathy: lowers blood ammonia levels by acidifying colonic contents, helping to improve neurological symptoms.

How It Works

  • Lactulose is a synthetic disaccharide that is not absorbed in the small intestine. In the colon, bacterial enzymes hydrolyze it to short‑chain fatty acids, which increase osmotic pressure and draw water into the lumen. The resulting acidification of colonic contents promotes the conversion of ammonia to ammonium, reducing its absorption into the bloodstream.

Side Effects

  • Lactulose may cause several adverse reactions, most of which are related to its laxative action.\n\nCommon Side Effects:\n- Abdominal cramping\n- Flatulence\n- Diarrhoea\n- Nausea\n- Bloating\n- Increased urgency to defecate\n\nSerious or Rare Side Effects:\n- Severe electrolyte imbalance (e.g., hyponatremia)\n- Dehydration\n- Acute colitis\n- Allergic reactions such as rash or urticaria\n- Severe abdominal pain\n- Persistent diarrhoea leading to malnutrition

Precautions & Warnings

  • Lactulose should be used with awareness of certain safety considerations.\n\nDose adjustment: tailor the dose to the individual response and clinical condition.\nRenal impairment: monitor electrolytes, especially potassium, during therapy.\nDiabetes mellitus: consider carbohydrate content when prescribing to patients with glucose control issues.\nPediatric use: use only under specialist supervision.\nPregnancy and lactation: evaluate risk‑benefit ratio before initiating therapy.\nStore at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Lactulose can interact with other medications and substances, affecting efficacy or safety.\n\nMajor Interactions (Avoid):\n- Antacids containing magnesium or aluminum: may reduce lactulose efficacy.\n- Oral antibiotics: can alter gut flora, potentially diminishing lactulose's ammonia‑lowering effect.\n\nModerate Interactions (Monitor Closely):\n- Diuretics: increased risk of electrolyte disturbances.\n- Insulin or oral hypoglycemics: monitor blood glucose due to carbohydrate load.\n- Potassium‑sparing agents: watch for hyperkalaemia when diarrhoea is present.

Frequently Asked Questions

Lattulosio Alter, containing lactulose, is indicated for the relief of constipation and for the management of hepatic encephalopathy, where it helps lower blood ammonia levels.

Lactulose is not absorbed in the small intestine; in the colon it is broken down by bacteria into short‑chain fatty acids. This creates an osmotic gradient that draws water into the bowel and acidifies the lumen, converting ammonia to ammonium and reducing its absorption.

The dose of Lattulosio Alter is determined by the prescribing clinician based on the patient’s condition, response, and tolerance. No fixed regimen is provided here.

Safety in pregnancy and lactation has not been definitively established. Clinicians should weigh potential benefits against possible risks before prescribing to pregnant or nursing women.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Lactulose is an osmotic laxative that works by increasing water content in the colon, unlike stimulant laxatives that trigger intestinal motility. It also has the unique benefit of reducing ammonia absorption, a property not shared by most other laxatives.

Store at ambient temperature: keep the product in its original container, protect it from moisture and direct sunlight, and ensure the storage area remains below 25 °C.

Lattulosio Alter is taken orally, usually as a liquid solution. The exact administration instructions, including timing and whether to mix with water, are provided by the prescribing healthcare professional.

Serious risks include severe electrolyte imbalance, dehydration, acute colitis, and rare allergic reactions. Patients should be monitored for signs of these conditions, especially if they experience persistent diarrhoea or abdominal pain.

Lattulosio Alter should be avoided in individuals with known hypersensitivity to lactulose, in patients with intestinal obstruction, and in those where the risk of severe electrolyte disturbance outweighs the benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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