Product image of Laurina (Desogestrel, Ethinylestradiol) supplied by GNH India

Laurina

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Laurina (Desogestrel, Ethinylestradiol)

Desogestrel, the active ingredient in Laurina, is a combined oral contraceptive presented as an oral tablet for oral use. It works together with ethinylestradiol, an estrogen component, to provide reliable cycle control and contraceptive efficacy for women of reproductive age.

GNH India supplies Laurina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aspen Pharma Trading Limited

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Indications & Clinical Uses

  • Laurina, a combined oral contraceptive, is used to prevent pregnancy by inhibiting ovulation and altering cervical mucus.
  • Contraception: prevents unintended pregnancy in women of childbearing potential.
  • Menstrual regulation: helps establish a regular menstrual cycle and reduces dysmenorrhea.
  • Acne management: improves acne associated with androgen excess in some patients.

How It Works

  • Desogestrel acts as a progestogenic agent that suppresses the hypothalamic‑pituitary‑ovarian axis, inhibiting the LH and FSH surge required for ovulation. Ethinylestradiol provides estrogenic feedback that stabilises the endometrium, thickens cervical mucus and enhances the contraceptive effect, together preventing fertilisation and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Breast tenderness: temporary swelling or discomfort.
  • Headache: occasional mild to moderate pain.
  • Breakthrough bleeding: spotting between periods.

Serious or Rare Side Effects

  • Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.
  • Arterial thrombosis: stroke or myocardial infarction.
  • Severe hypertension: sudden increase in blood pressure.
  • Allergic reactions: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before starting Laurina, consider the following precautions:

  • Medical evaluation: assess personal and family history of thromboembolic disorders.
  • Smoking: avoid use if over 35 years old and a smoker.
  • Medication review: check for interacting drugs that may affect efficacy.
  • Pregnancy: discontinue immediately if pregnancy is confirmed.
  • Breastfeeding: discuss potential risks with a healthcare professional.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and light.

Avoid Interactions

Laurina may interact with several medicines.

Major Interactions (Avoid)

  • Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin): markedly reduce contraceptive effectiveness.
  • St. John’s wort: decreases hormone levels, increasing risk of contraceptive failure.
  • Protease inhibitors (e.g., ritonavir): may elevate hormone concentrations and raise side‑effect risk.

Moderate Interactions (Monitor Closely)

  • Rifampin and other strong antibiotics: may lower efficacy, requiring cycle monitoring.
  • Azole antifungals (e.g., ketoconazole): can increase hormone levels, warranting observation for toxicity.
  • Selective serotonin reuptake inhibitors (e.g., fluoxetine): may affect hormone metabolism and require clinical vigilance.

Frequently Asked Questions

Laurina is a combined oral contraceptive containing desogestrel and ethinylestradiol. It is prescribed to prevent unintended pregnancy in women of reproductive age by suppressing ovulation and creating cervical mucus conditions that are unfavorable for fertilisation.

Desogestrel, a progestogen, inhibits the hypothalamic‑pituitary‑ovarian axis, preventing the LH and FSH surge needed for ovulation. Ethinylestradiol, an estrogen, provides feedback that stabilises the endometrium and thickens cervical mucus, together reducing the chance of fertilisation and implantation.

The specific dosing regimen for Laurina is determined by the prescribing healthcare professional. Typically, it involves taking one tablet daily at the same time each day, but the exact schedule and duration should follow the prescriber’s instructions.

Laurina is not intended for use during pregnancy; if pregnancy occurs, the product should be discontinued immediately. While limited data exist for breastfeeding, the decision to use Laurina while nursing should be made by a healthcare provider after weighing potential benefits and risks.

To order Laurina, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Laurina contains desogestrel, a third‑generation progestogen, which is associated with a lower incidence of androgenic side effects compared with some older progestins. Its efficacy in preventing pregnancy is comparable to other combined oral contraceptives, while the side‑effect profile may differ slightly based on individual tolerance.

Laurina tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct light, and keep out of reach of children. Do not refrigerate or freeze the tablets.

Laurina is taken orally with a glass of water, preferably at the same time each day. It is usually started on the first day of the menstrual cycle or after a 7‑day hormone‑free interval, as directed by a healthcare professional.

The most serious risks include venous thromboembolism (deep‑vein thrombosis or pulmonary embolism), arterial thrombosis (stroke or myocardial infarction), severe hypertension, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience symptoms suggestive of these conditions.

Laurina is contraindicated in women with a history of thromboembolic disorders, active or past breast cancer, uncontrolled hypertension, severe liver disease, known hypersensitivity to any component, or in those who are pregnant. Women over 35 who smoke should also avoid using this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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