Product image of Lavement Au Phosphate (Disodium Phosphate Dodecahydrate, Sodium Dihydrogen Phosphate Dihydrate) supplied by GNH India

Lavement Au Phosphate

Active Ingredient:
Disodium Phosphate Dodecahydrate, Sodium Dihydrogen Phosphate Dihydrate
Origin:
EU

Lavement Au Phosphate (Disodium Phosphate Dodecahydrate, Sodium Dihydrogen Phosphate Dihydrate)

Disodium Phosphate Dodecahydrate, the active ingredient in Lavement Au Phosphate, is an osmotic laxative presented as a rectal enema solution for rectal use. It treats constipation and is used for bowel cleansing prior to diagnostic procedures or surgery.

GNH India supplies Lavement Au Phosphate as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Nv/Sa

1
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Indications & Clinical Uses

Lavement Au Phosphate, an osmotic laxative, is employed to manage conditions requiring bowel evacuation.

  • Constipation: softens stool and promotes evacuation in patients with functional constipation.
  • Colonoscopy preparation: cleanses the colon to provide clear visualization during colonoscopic examination.
  • Pre‑operative bowel preparation: clears the rectum and colon before rectal or colonic surgery.

How It Works

  • Disodium Phosphate and Sodium Dihydrogen Phosphate create an osmotic gradient within the intestinal lumen. The resulting influx of water increases intraluminal volume, softens fecal material, and stimulates peristaltic activity, leading to accelerated bowel evacuation and effective colon cleansing.

Side Effects

Common Side Effects

  • Abdominal cramping: mild to moderate discomfort in the lower abdomen.
  • Nausea: transient feeling of queasiness after administration.
  • Mild diarrhea: loose stools occurring shortly after the enema.
  • Rectal irritation: temporary burning or itching at the site of administration.
  • Electrolyte imbalance (mild): slight changes in serum phosphate or calcium levels.
  • Transient thirst: increased desire to drink fluids.

Serious or Rare Side Effects

  • Hyperphosphatemia: elevated blood phosphate that may affect calcium balance.
  • Severe electrolyte disturbances: significant shifts in potassium, calcium, or magnesium.
  • Renal impairment: worsening kidney function in susceptible individuals.
  • Allergic reaction (anaphylaxis): rare but potentially life‑threatening hypersensitivity.
  • Severe abdominal pain: intense pain indicating possible complications.
  • Colonic perforation: rare tearing of the colon wall requiring emergency care.

Precautions & Warnings

Before using Lavement Au Phosphate, consider the following safety measures.

  • Assess renal function: avoid in patients with severe renal insufficiency.
  • Monitor electrolytes: especially phosphate, calcium, and potassium levels.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Use with caution in the elderly: increased risk of dehydration and electrolyte shifts.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Lavement Au Phosphate may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Calcium supplements: can precipitate calcium phosphate, reducing enema efficacy.
  • Magnesium‑containing antacids: may increase phosphate absorption and risk of hyperphosphatemia.
  • Intravenous phosphate solutions: concurrent use can cause dangerous phosphate overload.

Moderate Interactions (Monitor Closely)

  • Diuretics: monitor electrolyte status closely.
  • ACE inhibitors or ARBs: watch for changes in renal function.
  • Lithium: observe serum lithium levels due to possible altered renal clearance.

Frequently Asked Questions

Lavement Au Phosphate is a rectal enema solution used to relieve constipation and to cleanse the colon before procedures such as colonoscopy or before rectal and colonic surgery. It works by drawing water into the bowel, softening stool and promoting evacuation.

Disodium Phosphate creates an osmotic gradient in the colon that pulls water from surrounding tissues into the intestinal lumen. The increased fluid volume softens fecal matter and stimulates peristalsis, leading to rapid bowel evacuation and effective colon cleansing.

The dose of Lavement Au Phosphate is determined by the prescribing healthcare professional based on the patient’s condition, age, and clinical needs. The prescriber will specify the volume and frequency appropriate for each individual case.

Safety data for Lavement Au Phosphate in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lavement Au Phosphate is an osmotic laxative that works locally in the colon, whereas many alternative agents (e.g., polyethylene glycol solutions) are oral and act systemically. The enema provides rapid, targeted cleansing with a smaller fluid volume, but may be less suitable for patients who cannot tolerate rectal administration.

Store the enema at room temperature, away from direct sunlight and moisture. Keep the container tightly closed and in its original packaging until use. Do not freeze or expose the solution to extreme temperatures, as this could affect its stability.

The product is administered rectally as an enema. The patient lies on their left side, inserts the nozzle into the rectum, and gently squeezes the prescribed volume of solution. The enema is retained for the time recommended by the prescriber before evacuation.

Serious risks include hyperphosphatemia, severe electrolyte disturbances, renal impairment, allergic reactions such as anaphylaxis, and, in rare cases, colonic perforation. Patients should be monitored for signs of these complications, especially if they have underlying kidney disease or electrolyte disorders.

Lavement Au Phosphate should be avoided in individuals with severe renal insufficiency, known hypersensitivity to phosphate enemas, uncontrolled electrolyte imbalances, or active gastrointestinal obstruction. It should also be used with caution in pregnant or lactating women and in elderly patients prone to dehydration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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