Product image of Lavirk (Aciclovir) supplied by GNH India

Lavirk

Active Ingredient:
Aciclovir
Origin:
EU

Lavirk (Aciclovir)

Aciclovir, the active ingredient in Lavirk, is an antiviral presented as a topical formulation for topical use. It treats herpes simplex virus infections of the skin, mucous membranes and eyes, including cold sores, genital herpes and ocular herpes, helping to reduce lesion duration and symptom severity.

GNH India supplies Lavirk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product conforms to EU regulatory standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Kern Pharma, S.L.

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Indications & Clinical Uses

Aciclovir is used to manage viral infections caused by herpes simplex viruses affecting the skin and mucous membranes.

  • Herpes labialis (cold sores): shortens healing time and eases pain.
  • Genital herpes (initial outbreaks): reduces lesion size and discomfort.
  • Herpes simplex keratitis (ocular infection): controls viral replication and promotes corneal healing.

How It Works

  • After topical application, aciclovir is phosphorylated by viral thymidine kinase to aciclovir monophosphate, then further converted by cellular kinases to the active triphosphate. The triphosphate competitively inhibits viral DNA polymerase, terminating DNA chain elongation and preventing viral replication within infected cells.

Side Effects

Aciclovir topical therapy is generally well tolerated, but local and systemic reactions can occur.

Common Side Effects

  • Application site irritation: mild redness or discomfort at the site.
  • Burning sensation: transient feeling of warmth after application.
  • Itching: occasional pruritus around the treated area.
  • Dryness: skin may become slightly dry or flaky.

Serious or Rare Side Effects

  • Allergic contact dermatitis: rash, swelling, or blistering.
  • Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention.
  • Ocular toxicity: if applied to the eye in non‑ophthalmic form, may cause irritation or corneal damage.
  • Systemic hypersensitivity: rare anaphylactic reactions.

Precautions & Warnings

When using Lavirk, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Renal impairment: monitor for increased systemic absorption, especially with extensive application.
  • Lesion selection: apply only to confirmed herpes lesions; avoid healthy skin.
  • Ocular exposure: do not apply to the eye unless using an ophthalmic preparation.
  • Store at room temperature: keep in the original container, protect from moisture and direct heat.

Avoid Interactions

Aciclovir topical has limited systemic interactions, but certain co‑administered agents may affect safety or efficacy.

Major Interactions (Avoid)

  • Probenecid: may increase systemic aciclovir levels if absorbed.
  • Nephrotoxic drugs: monitor renal function when extensive topical use is combined.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may reduce antiviral effectiveness.
  • Immunosuppressants: could delay lesion healing.
  • Other topical agents: may increase local irritation when used together.

Frequently Asked Questions

Lavirk contains aciclovir and is indicated for the topical treatment of herpes simplex virus infections, including cold sores (herpes labialis), genital herpes lesions, and ocular herpes (herpes simplex keratitis). It helps to reduce lesion duration, pain, and viral replication at the site of application.

Aciclovir is taken up by virus‑infected cells and phosphorylated by viral thymidine kinase to a monophosphate, then to the active triphosphate by cellular enzymes. The triphosphate competitively inhibits viral DNA polymerase, halting DNA chain elongation and preventing the virus from replicating.

The dosing regimen for Lavirk is determined by the prescribing clinician based on the type, location and severity of the herpes lesion. Typical regimens involve applying a thin layer to the affected area several times daily for a prescribed number of days, but exact instructions must come from a qualified healthcare professional.

Data on topical aciclovir use during pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing Lavirk to pregnant or breastfeeding individuals. Consultation with a medical professional is essential.

To order Lavirk, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Lavirk (aciclovir) and alternative topical antivirals such as penciclovir share a similar mechanism of inhibiting viral DNA synthesis. Aciclovir has a well‑established safety profile and is effective for a broad range of herpes lesions, while penciclovir may offer slightly longer intracellular retention. Choice depends on clinical judgment, lesion type and patient tolerance.

Store Lavirk at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and excessive heat. Keep the container tightly closed when not in use to maintain stability and potency.

Lavirk is applied topically to clean, dry skin. Use a thin layer over the affected area, typically 5 minutes before bedtime and again in the morning, unless otherwise directed by a healthcare professional. Wash hands before and after application to avoid accidental spread to other body sites.

Serious adverse reactions are rare but may include allergic contact dermatitis, Stevens‑Johnson syndrome, or severe ocular irritation if used incorrectly. Any signs of widespread rash, blistering, swelling, or vision changes require immediate medical attention and discontinuation of the product.

Lavirk should be avoided in individuals with a known hypersensitivity to aciclovir or any component of the formulation. It is also contraindicated for use on healthy, non‑infected skin, and ocular application should be limited to the ophthalmic version of the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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