Product image of Laxabon (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Sodium Sulfate Anhydrous, Macrogol 3) supplied by GNH India

Laxabon

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Sodium Sulfate Anhydrous, Macrogol 3
Origin:
EU

Laxabon (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Sodium Sulfate Anhydrous, Macrogol 3)

Polyethylene glycol (macrogol), the active ingredient in Laxabon, is an osmotic laxative presented as an oral solution for oral use. It is indicated for the relief of constipation in adults and children.
GNH India supplies Laxabon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Karo Pharma Ab

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Indications & Clinical Uses

  • Laxabon, an osmotic laxative, is used to manage constipation by increasing water content in the intestinal lumen.
  • Constipation: softens stool and promotes regular bowel movements in occasional or chronic cases.
  • Opioid‑induced constipation: alleviates reduced gastrointestinal motility caused by opioid therapy.
  • Functional constipation: improves stool frequency and consistency in patients with functional bowel disorders.

How It Works

  • Polyethylene glycol creates an osmotic gradient within the intestinal lumen that retains water, increasing stool volume and softness. The electrolyte components help maintain fluid balance while the polymer is not absorbed, allowing it to act locally to stimulate peristalsis and facilitate bowel evacuation without systemic activity.

Side Effects

Laxabon may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating or distension
  • Flatulence or gas
  • Nausea or mild stomach upset
  • Diarrhea or loose stools
  • Headache
  • Mild abdominal cramping

Serious or Rare Side Effects

  • Severe electrolyte imbalance (e.g., hyponatremia, hypokalemia)
  • Marked dehydration
  • Allergic reactions including rash, itching, or anaphylaxis
  • Persistent severe abdominal pain
  • Rectal bleeding or severe gastrointestinal irritation

Precautions & Warnings

Before using Laxabon, consider the following safety measures.

  • Renal function assessment: evaluate kidney status, especially in patients with renal impairment.
  • Electrolyte monitoring: check serum electrolytes in prolonged or high‑volume use.
  • Caution in the elderly: increased risk of dehydration and electrolyte shifts.
  • Avoid in bowel obstruction or perforation: contraindicated where intestinal blockage exists.
  • Do not exceed prescribed volume: follow prescriber instructions to prevent over‑hydration.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Laxabon can interact with other medications that affect fluid or electrolyte balance.

Major Interactions (Avoid)

  • Concurrent use of other osmotic laxatives: may cause excessive fluid loss.
  • Mineral oil: can impair absorption of fat‑soluble vitamins and increase risk of steatorrhea.
  • High‑dose electrolyte solutions: may lead to dangerous electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • Diuretics: monitor for additive electrolyte depletion.
  • Antacids containing sodium or potassium: watch for cumulative electrolyte load.
  • NSAIDs: increased risk of gastrointestinal irritation.
  • ACE inhibitors or ARBs: potential for altered potassium levels.

Frequently Asked Questions

Laxabon is an oral osmotic laxative indicated for the relief of constipation, including functional constipation and opioid‑induced constipation. It works by increasing water content in the stool, making bowel movements easier and more regular.

Polyethylene glycol in Laxabon creates an osmotic gradient that draws water into the intestinal lumen. The retained water softens the stool and expands its volume, stimulating peristalsis and facilitating the passage of feces without being absorbed into the bloodstream.

The appropriate dose of Laxabon is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of constipation, and clinical response. Patients should follow the prescriber’s instructions and not adjust the volume on their own.

Safety data for Laxabon in pregnancy and lactation are limited. Healthcare providers usually weigh the benefits against potential risks before prescribing. Women who are pregnant or breastfeeding should discuss use with their physician to determine if it is appropriate for their situation.

To order Laxabon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with stimulant laxatives, Laxabon (polyethylene glycol) works locally without stimulating intestinal nerves, resulting in a gentler, more physiologic effect. Unlike bulk‑forming agents, it does not rely on fiber intake. Its electrolyte formulation helps maintain fluid balance, making it suitable for patients needing controlled osmotic action.

Laxabon should be stored at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and store it in its original packaging to preserve stability and potency.

Laxabon is taken orally as a measured liquid solution. The prescribed volume is mixed with a suitable amount of water or other clear fluid, shaken gently if needed, and consumed according to the healthcare provider’s directions, usually once daily or as instructed.

Serious risks include severe electrolyte imbalance (such as hyponatremia or hypokalemia), marked dehydration, and rare allergic reactions that may present as rash, swelling, or anaphylaxis. Patients experiencing these symptoms should seek immediate medical attention.

Laxabon is contraindicated in individuals with known or suspected bowel obstruction, perforation, or severe inflammatory bowel disease. Patients with significant renal impairment, uncontrolled electrolyte disorders, or hypersensitivity to any component of the formulation should avoid its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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