Product image of Laxido Orange (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Laxido Orange

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Laxido Orange (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Laxido Orange, is an osmotic laxative presented as an oral powder for oral use. It works by retaining water in the intestinal lumen, thereby softening stool and facilitating regular bowel movements in adults and adolescents with functional constipation.

GNH India supplies Laxido Orange as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for cross‑border distribution, including customs documentation and temperature‑controlled logistics where required.

Manufacturer / TM Owner

Galen Limited

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Indications & Clinical Uses

Laxido Orange, an osmotic laxative, is used to manage constipation by increasing intestinal water content.

  • Functional constipation: helps achieve regular bowel movements.
  • Opioid‑induced constipation: alleviates reduced motility caused by opioid therapy.
  • Chronic idiopathic constipation: improves stool frequency and consistency.
  • Bowel preparation for diagnostic procedures: facilitates cleansing of the colon before colonoscopy or imaging.

How It Works

  • Macrogol 3350 creates an osmotic gradient within the gastrointestinal tract that draws water into the intestinal lumen. The increased fluid content softens fecal mass, expands stool volume, and stimulates peristaltic activity, thereby promoting the passage of stool without being absorbed systemically.

Side Effects

Laxido Orange may cause a range of adverse reactions.

Common Side Effects

  • Abdominal bloating: mild distension of the abdomen.
  • Flatulence: increased intestinal gas.
  • Nausea: feeling of queasiness.
  • Mild abdominal pain: transient cramping.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal sodium or potassium levels.
  • Severe dehydration: excessive fluid loss.
  • Allergic reaction: rash, itching, or angioedema.
  • Intestinal obstruction: blockage of the bowel.

Precautions & Warnings

Before using Laxido Orange, consider the following precautions.

  • Renal function assessment: evaluate kidney health to avoid fluid overload.
  • Electrolyte monitoring: check sodium and potassium levels during prolonged use.
  • Bowel obstruction caution: avoid in patients with known mechanical obstruction.
  • Hypersensitivity check: discontinue if allergic reactions occur.
  • Elderly dose adjustment: consider lower doses for older adults.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Laxido Orange can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Sodium‑containing medications: risk of hypernatremia.
  • Potassium‑sparing diuretics: potential hyperkalemia.
  • Lithium: altered lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: possible reduced efficacy.
  • NSAIDs: increased risk of renal impairment.

Frequently Asked Questions

Laxido Orange is an oral osmotic laxative indicated for the relief of occasional constipation, including functional constipation and constipation caused by opioid therapy. It works by increasing water content in the intestines to soften stool and promote regular bowel movements.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not absorbed from the gut. It creates an osmotic gradient that draws water into the intestinal lumen, softening stool, expanding its volume, and stimulating peristalsis, which together facilitate the passage of feces.

The appropriate dose of Laxido Orange is determined by the prescribing healthcare professional based on the patient’s age, severity of constipation, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for Laxido Orange in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks before prescribing it to pregnant or breastfeeding women. Consultation with a medical professional is essential.

To order Laxido Orange, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Laxido Orange (a polyethylene glycol‑based osmotic laxative) generally has a gentler onset and fewer cramping side effects. Unlike saline laxatives, it does not significantly alter electrolyte balance when used as directed, making it suitable for longer‑term management of chronic constipation.

Laxido Orange should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep the product out of direct sunlight and away from sources of humidity.

Laxido Orange is taken orally, usually dissolved in a specified amount of water or another clear fluid as instructed by the prescriber. The solution should be consumed promptly after preparation to ensure optimal efficacy.

Serious risks include severe electrolyte disturbances such as hypernatremia or hyperkalemia, marked dehydration, and rare allergic reactions like rash or angioedema. Patients experiencing severe abdominal pain, persistent diarrhea, or signs of an allergic response should seek medical attention immediately.

Laxido Orange should be avoided in individuals with known hypersensitivity to any of its ingredients, those with complete intestinal obstruction, or patients with severe renal impairment without medical supervision. Consultation with a healthcare professional is required before use in these populations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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