Product image of Laxido Paediatric Plain (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Laxido Paediatric Plain

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Laxido Paediatric Plain (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, Sodium Hydrogen Carbonate, Potassium Chloride and Sodium Chloride, the active ingredients in Laxido Paediatric Plain, are a laxative presented as an oral powder for oral administration. The formulation is intended for children and works by retaining water in the intestinal lumen to soften stool and promote regular bowel movements in pediatric constipation.

GNH India supplies Laxido Paediatric Plain as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing EU‑origin products that meet stringent quality standards.

Manufacturer / TM Owner

Galen Pharma Ireland Limited

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Indications & Clinical Uses

  • Laxido Paediatric Plain, an osmotic laxative, is used to manage constipation and related bowel disorders in children.
  • Functional constipation: helps restore regular bowel movements by softening stools.
  • Encopresis secondary to constipation: reduces stool hardness and frequency of soiling.
  • Fecal impaction prevention: maintains stool softness to avoid blockage in pediatric patients.

How It Works

  • Macrogol 3350 creates an osmotic gradient that draws water into the intestinal lumen, increasing stool water content and volume. The accompanying electrolytes—sodium hydrogen carbonate, potassium chloride and sodium chloride—maintain electrolyte balance while enhancing the osmotic effect. The resulting softened, bulkier stool stimulates peristalsis, facilitating easier passage through the colon. This mechanism operates locally within the gut without systemic absorption of the polymer.

Side Effects

Laxido Paediatric Plain may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating
  • Flatulence
  • Nausea
  • Diarrhea

Serious or Rare Side Effects

  • Severe electrolyte imbalance
  • Dehydration
  • Allergic reaction (rash, itching, swelling)
  • Persistent abdominal pain

Precautions & Warnings

  • When using Laxido Paediatric Plain, certain precautions should be observed to ensure safety and effectiveness.
  • Assess electrolyte status: check baseline sodium, potassium and chloride levels before initiating therapy.
  • Use under medical supervision: dosage should be individualized by a healthcare professional.
  • Adjust for renal impairment: monitor kidney function and modify dose if necessary.
  • Monitor for dehydration: ensure adequate fluid intake during treatment.
  • Avoid in intestinal obstruction: contraindicated in patients with known bowel blockage.
  • Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Laxido Paediatric Plain can interact with other medicines, affecting electrolyte balance or gastrointestinal function.

Major Interactions (Avoid)

  • Concurrent use with other osmotic laxatives: risk of severe electrolyte disturbances.
  • Combination with loop diuretics: may exacerbate potassium loss and dehydration.

Moderate Interactions (Monitor Closely)

  • Antacids containing magnesium or aluminum: may alter absorption of the polymer.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): increase risk of gastrointestinal irritation.
  • Mineral supplements (e.g., calcium, iron): can affect stool consistency and electrolyte levels.

Frequently Asked Questions

Laxido Paediatric Plain is an oral osmotic laxative indicated for the relief of constipation in children. It works by increasing the water content of stool, making it softer and easier to pass, and is commonly prescribed for functional constipation and related pediatric bowel disorders.

Macrogol 3350 is a high‑molecular‑weight polymer that remains in the intestinal lumen and draws water osmotically into the bowel. The added water softens the stool and expands its volume, which stimulates peristalsis and promotes regular bowel movements without being absorbed into the bloodstream.

The dose of Laxido Paediatric Plain is individualized by a qualified prescriber based on the child’s age, weight, severity of constipation, and response to therapy. Healthcare professionals calculate the appropriate amount and provide specific instructions for preparation and administration.

Safety data for Laxido Paediatric Plain in pregnancy or lactation are limited. It is generally recommended to avoid use unless clearly needed and prescribed by a physician. Women who are pregnant or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting treatment.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details and any necessary import documentation.

Laxido Paediatric Plain belongs to the osmotic laxative class, similar to lactulose or polyethylene glycol‑based products. Compared with stimulant laxatives, it generally has a gentler onset and a lower risk of cramping. Its electrolyte‑balanced formulation helps maintain serum levels, making it a preferred option for children who need a mild, effective laxative.

The product should be stored at ambient temperature, below 25 °C, in its original container. Keep it away from moisture, direct sunlight and heat sources. Ensure the packaging is tightly closed after each use to maintain product stability and prevent contamination.

Laxido Paediatric Plain is supplied as a powder that is dissolved in a measured amount of water or a suitable clear fluid. The resulting solution is given orally, usually once daily, according to the dose prescribed by the treating physician. The mixture should be consumed promptly after preparation.

The most serious risks include severe electrolyte imbalance, particularly low potassium or sodium levels, and dehydration, which can occur if fluid intake is insufficient. An allergic reaction presenting as rash, itching, swelling, or difficulty breathing is also a rare but critical concern that requires immediate medical attention.

Laxido Paediatric Plain should not be used in children with known or suspected intestinal obstruction, severe renal impairment, or a documented hypersensitivity to any of its ingredients. It is also contraindicated in patients who are already receiving high‑dose osmotic laxatives or diuretics without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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