Product image of Laxido (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Laxido

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Laxido (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Laxido, is an osmotic laxative presented as an oral solution for oral use. It is indicated for the relief of constipation in adults and children, helping to soften stool and promote regular bowel movements.

GNH India supplies Laxido as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution, including temperature‑controlled shipping where required, and comprehensive regulatory support globally.

Manufacturer / TM Owner

Galen Pharma Ireland Limited

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Indications & Clinical Uses

  • Laxido, an osmotic laxative, acts on the gastrointestinal tract to alleviate constipation.
  • Constipation: softens stool and facilitates regular bowel movements in patients with functional constipation.
  • Functional constipation: increases stool water content to improve frequency and ease of passage.
  • Opioid‑induced constipation: counteracts reduced intestinal motility caused by opioid therapy.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not absorbed systemically. It remains in the intestinal lumen where it binds water molecules osmotically, increasing the fluid volume of the stool. The resulting softening of fecal mass and enhanced peristalsis promote spontaneous bowel movements without stimulating intestinal receptors. The osmotic effect also dilutes intestinal contents, reducing transit time and facilitating defecation.

Side Effects

Laxido may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating
  • Flatulence
  • Nausea
  • Diarrhea

Serious or Rare Side Effects

  • Severe electrolyte imbalance
  • Marked dehydration
  • Allergic reactions (rash, angioedema)

Precautions & Warnings

  • Before using Laxido, consider the following precautions.
  • Assess renal function: evaluate kidney status before initiating therapy in patients with renal impairment.
  • Monitor electrolytes: check serum electrolytes periodically during prolonged use.
  • Use cautiously in bowel obstruction: avoid if mechanical obstruction is suspected.
  • Adjust dose in elderly: start with lower volume to reduce risk of dehydration.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Laxido can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Concomitant use with other osmotic laxatives: risk of severe electrolyte disturbances.
  • Loop diuretics: increased risk of dehydration and electrolyte loss.
  • Mineral oil: may reduce efficacy of macrogol.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may diminish laxative effect.
  • NSAIDs: potential additive gastrointestinal irritation.
  • Calcium supplements: may interfere with stool water binding.

Frequently Asked Questions

Laxido is an oral osmotic laxative indicated for the relief of constipation. It works by increasing the water content of stool, making it softer and easier to pass, and is used in both adult and pediatric patients who need assistance with regular bowel movements.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that stays within the intestinal lumen. It binds water osmotically, raising the fluid volume of the stool. This softens the fecal mass and stimulates peristalsis, facilitating spontaneous bowel movements without being absorbed into the bloodstream.

The appropriate dose of Laxido is individualized and set by a qualified prescriber based on the patient’s age, weight, severity of constipation, and response to therapy. Dosing instructions are provided on the product label and should be followed exactly as directed by the healthcare professional.

Safety data for Laxido in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using this medication.

To order Laxido, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Laxido (macrogol 3350) works by osmotic water retention rather than stimulating intestinal muscles, resulting in a gentler, more physiological effect and a lower incidence of cramping. It is also preferred over bulk‑forming agents for patients who need rapid stool softening.

Laxido should be stored at ambient temperature, below 25 °C, in its original container. Keep the solution away from moisture, direct sunlight and extreme heat. Ensure the bottle is tightly closed after each use to maintain product stability.

Laxido is supplied as an oral solution. The prescribed volume is measured with a calibrated dosing device and taken orally, usually once daily or as directed by the prescriber. It can be mixed with a small amount of water or a clear fluid if preferred, but should be consumed promptly.

Serious risks, although rare, include severe electrolyte imbalance, marked dehydration, and allergic reactions such as rash or angioedema. Patients should seek immediate medical attention if they experience symptoms like rapid heartbeat, muscle weakness, severe abdominal pain, or signs of an allergic response.

Laxido should be avoided in individuals with known hypersensitivity to macrogol or any of its excipients, in patients with intestinal obstruction, perforation, or severe inflammatory bowel disease, and in those for whom electrolyte disturbances would pose a significant risk. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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