Product image of Laxido (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Laxido

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Laxido (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350, the active ingredient in Laxido, is an osmotic laxative presented as an oral powder for solution for oral use. It is used to relieve constipation and to aid bowel cleansing before diagnostic procedures.
GNH India supplies Laxido as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Intergal Pharma Ireland Limited

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Indications & Clinical Uses

Laxido is an osmotic laxative that works within the gastrointestinal tract to manage constipation and assist bowel preparation.

  • Chronic constipation: softens stool and increases bowel frequency in adults and children with persistent constipation.
  • Opioid‑induced constipation: provides effective relief of reduced motility caused by opioid therapy.
  • Bowel preparation for diagnostic procedures: can be incorporated into a cleansing regimen prior to colonoscopy or similar examinations.

How It Works

  • Macrogol 3350 creates an osmotic gradient that retains water in the intestinal lumen, increasing stool volume and softness. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help maintain fluid and electrolyte balance while promoting the movement of water into the bowel, facilitating peristalsis and bowel evacuation.

Side Effects

Laxido may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating
  • Flatulence
  • Nausea
  • Abdominal cramps
  • Diarrhoea
  • Headache

Serious or Rare Side Effects

  • Severe electrolyte imbalance (hyper‑ or hyponatraemia, hyperkalaemia)
  • Allergic reaction (rash, itching, swelling)
  • Dehydration
  • Renal impairment in susceptible patients
  • Severe abdominal pain
  • Anaphylaxis

Precautions & Warnings

When using Laxido, consider the following safety measures.

  • Assess renal function: patients with impaired kidneys may accumulate electrolytes.
  • Monitor electrolytes: especially sodium and potassium during prolonged therapy.
  • Avoid in intestinal obstruction: risk of perforation or worsening blockage.
  • Use caution in elderly: increased susceptibility to dehydration and electrolyte shifts.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Laxido can interact with other medicines that affect electrolyte balance or renal function.

Major Interactions (Avoid)

  • Concurrent high‑dose potassium supplements: risk of hyperkalaemia.
  • Loop diuretics: may increase electrolyte loss.
  • Other osmotic laxatives: additive effect causing severe diarrhoea.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: monitor serum potassium levels.
  • NSAIDs: watch renal function during combined use.

Frequently Asked Questions

Laxido is an oral osmotic laxative indicated for the relief of chronic constipation and for bowel cleansing before diagnostic procedures such as colonoscopy. It works by drawing water into the intestines, softening stool and promoting regular bowel movements.

The primary active component, macrogol 3350, is a large, non‑absorbable polymer that creates an osmotic gradient, retaining water in the intestinal lumen. The accompanying electrolytes help maintain fluid balance while the increased water content softens stool and stimulates peristalsis.

The dose of Laxido is individualized by the prescribing healthcare professional based on the patient’s age, condition, and response to therapy. Patients should follow the prescriber’s instructions and the product label for preparation and administration.

Safety data for Laxido in pregnancy and lactation are limited. It should only be used if clearly needed and after a risk‑benefit assessment by a qualified healthcare provider. Women who are pregnant or breastfeeding should discuss alternatives with their doctor.

To place an order, submit an enquiry on the Laxido product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Laxido, containing macrogol 3350, is an osmotic laxative that generally provides a gentler, more predictable effect compared with stimulant laxatives such as bisacodyl. It is less likely to cause cramping and is suitable for long‑term use, whereas stimulant agents act quickly but may lead to dependence.

Laxido should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture. Keep the product away from direct sunlight and out of reach of children.

Laxido is supplied as a powder that is dissolved in water according to the instructions on the label. The solution is taken orally, usually once daily, or as directed by a healthcare professional for bowel preparation protocols.

Serious risks include severe electrolyte disturbances such as hyperkalaemia or hyponatraemia, dehydration, and rare allergic reactions that may present as rash, swelling or anaphylaxis. Patients with renal impairment or intestinal obstruction should be monitored closely.

Laxido is contraindicated in patients with known hypersensitivity to any component, in those with intestinal obstruction, perforation, or severe inflammatory bowel disease, and in individuals with significant renal failure unless closely supervised by a physician.

Published by

GNH India Pharmaceuticals Limited

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Last updated:

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