Product image of Laxoberon (Sodium Picosulfate Monohydrate) supplied by GNH India

Laxoberon

Active Ingredient:
Sodium Picosulfate Monohydrate
Origin:
EU

Laxoberon (Sodium Picosulfate Monohydrate)

Sodium Picosulfate Monohydrate, the active ingredient in Laxoberon, is a stimulant laxative presented as an oral formulation for oral use. It is employed in adult patients to relieve constipation and to cleanse the bowel safely and effectively before any diagnostic or surgical procedures. GNH India supplies Laxoberon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance, regulatory compliance, and a distribution network that ensures timely delivery and support for clinical needs across multiple regions.

Manufacturer / TM Owner

Opella Healthcare Belgium (Handelsnaam Sanofi Belgium)

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Indications & Clinical Uses

Sodium Picosulfate Monohydrate is a stimulant laxative that acts on colonic motility and is used for bowel cleansing in various clinical settings.

  • Constipation: Promotes bowel movements in patients with functional constipation.
  • Bowel preparation for colonoscopy: Provides effective colonic cleansing before colonoscopy.
  • Bowel preparation for surgery: Clears the intestinal tract prior to surgical interventions.
  • Diagnostic imaging (e.g., CT colonography): Facilitates clear imaging by emptying the colon.
  • Pre‑operative bowel cleansing: Reduces fecal load before abdominal surgery.

How It Works

  • After oral administration, sodium picosulfate monohydrate reaches the colon where resident bacterial enzymes convert it to the active metabolite, bis‑(p‑hydroxyphenyl)‑pyridyl‑methane. The metabolite stimulates enteric nerves, enhancing peristaltic contractions and promoting secretion of water and electrolytes into the lumen, which together accelerate intestinal transit and facilitate evacuation of fecal material.

Side Effects

Sodium picosulfate monohydrate may cause a range of adverse reactions, most of which are related to its laxative activity.

Common Side Effects

  • Abdominal cramps
  • Diarrhea
  • Nausea

Serious or Rare Side Effects

  • Severe dehydration
  • Electrolyte imbalance (e.g., hyponatremia, hypokalemia)
  • Allergic reactions (rash, pruritus, angioedema)

Precautions & Warnings

When using Laxoberon, consider the following safety measures.

  • Assess renal function: Use with caution in patients with severe renal impairment.
  • Avoid in intestinal obstruction: Do not administer when acute blockage is present.
  • Monitor electrolytes: Check serum electrolytes before and during prolonged therapy.
  • Do not combine with other stimulant laxatives: Reduces safety and may increase adverse effects.
  • Pregnancy and breastfeeding: Safety not established; consult a healthcare professional before use.
  • Store at ambient temperature: Keep in original packaging, protect from moisture and heat.

Avoid Interactions

Sodium picosulfate monohydrate can interact with several drug classes; awareness helps manage risk.

Major Interactions (Avoid)

  • Anticholinergic agents: May diminish laxative efficacy.
  • Opioid analgesics: Counteract stimulant effect, reducing bowel movement.
  • Lithium therapy: Risk of electrolyte disturbances leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics: May exacerbate fluid loss; monitor hydration.
  • Antihypertensives: Potential additive hypotensive effect due to fluid shifts.
  • Magnesium‑containing antacids: Can increase laxative effect and risk of diarrhea.

Frequently Asked Questions

Laxoberon contains sodium picosulfate monohydrate and is used as a stimulant laxative to relieve constipation and to cleanse the bowel before diagnostic procedures such as colonoscopy or before surgical interventions that require a clean intestinal tract.

After oral intake, colonic bacteria convert sodium picosulfate monohydrate into an active metabolite that stimulates enteric nerves, increasing peristaltic activity and promoting secretion of water and electrolytes into the intestinal lumen, which together accelerate bowel transit and facilitate evacuation.

The appropriate dose of Laxoberon is determined by the prescribing healthcare professional based on the patient’s condition, age, renal function and the specific bowel‑cleansing protocol required for the planned procedure.

Safety of sodium picosulfate monohydrate in pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Laxoberon.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Laxoberon belongs to the stimulant‑laxative class, which acts by stimulating colonic nerves, unlike osmotic agents that draw water into the lumen. It generally produces a rapid bowel movement and is preferred for bowel‑preparation protocols, whereas osmotic laxatives may be used for chronic constipation with a gentler effect.

Laxoberon should be stored at ambient temperature, below 25 °C, in its original container. Keep the product away from moisture, direct sunlight and heat to maintain its stability and efficacy.

Laxoberon is taken orally, usually as a single dose or divided doses as directed by a healthcare professional. The tablet (or oral preparation) is swallowed with water, and the patient should follow any specific timing instructions related to the upcoming diagnostic or surgical procedure.

The most serious risks include severe dehydration, significant electrolyte disturbances such as hyponatremia or hypokalemia, and rare allergic reactions that may manifest as rash, itching, or angioedema. Prompt medical attention is required if any of these serious symptoms occur.

Laxoberon should be avoided in individuals with known hypersensitivity to sodium picosulfate, acute intestinal obstruction, severe renal impairment, or in patients for whom rapid bowel evacuation is contraindicated. A physician should evaluate suitability before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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