Product image of Laxolen (Sodium Citrate, Sodium Lauryl Sulfoacetate) supplied by GNH India

Laxolen

Active Ingredient:
Sodium Citrate, Sodium Lauryl Sulfoacetate
Origin:
EU

Laxolen (Sodium Citrate, Sodium Lauryl Sulfoacetate)

Sodium Citrate and Sodium Lauryl Sulfoacetate, the active ingredient in Laxolen, is a laxative presented as a rectal preparation for rectal use. It treats constipation by softening stool and facilitating bowel movements in adults.

GNH India supplies Laxolen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratórios Basi – Indústria Farmacêutica, S.A.

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Indications & Clinical Uses

  • Laxolen is a laxative indicated for conditions affecting bowel motility and stool consistency.
  • Constipation: softens stool and promotes regular bowel movements.
  • Post‑operative constipation: helps restore normal transit after surgical procedures.
  • Opioid‑induced constipation: provides osmotic activity to counteract opioid‑related slowdown of intestinal motility.

How It Works

  • Sodium citrate creates an osmotic gradient that draws water into the intestinal lumen, increasing stool water content and softening the mass. Sodium lauryl sulfoacetate acts as a surfactant, reducing surface tension of the stool, which further facilitates its passage through the rectum and colon, resulting in a bowel movement.

Side Effects

Laxolen may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal cramping or discomfort.
  • Mild rectal irritation or burning.
  • Diarrhea or loose stools.
  • Flatulence or bloating.

Serious or Rare Side Effects

  • Severe electrolyte imbalance (e.g., hyponatremia).
  • Persistent or worsening abdominal pain requiring medical evaluation.

Precautions & Warnings

Before using Laxolen, consider the following safety measures.

  • Assess renal function: avoid use in severe renal impairment without medical supervision.
  • Monitor electrolyte status: prolonged use may affect sodium balance.
  • Use with caution in patients with inflammatory bowel disease or bowel obstruction.
  • Avoid concurrent use with other osmotic or stimulant laxatives unless directed by a clinician.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Laxolen can interact with certain medications, altering their absorption or electrolyte balance.

Major Interactions (Avoid)

  • Lithium: increased risk of lithium toxicity due to altered sodium balance.
  • Digoxin: electrolyte shifts may predispose to digoxin toxicity.

Moderate Interactions (Monitor Closely)

  • Oral antibiotics: reduced absorption may diminish efficacy.
  • Antacids containing aluminum or magnesium: may affect stool consistency.
  • Other laxatives or stool softeners: additive effects can lead to excessive diarrhea.

Frequently Asked Questions

Laxolen is indicated for the relief of constipation. It works by softening stool and promoting bowel movements, making it useful for occasional constipation, post‑operative bowel slowdown, and opioid‑induced constipation in adult patients.

Sodium citrate acts as an osmotic agent. When administered rectally, it draws water into the intestinal lumen, increasing stool hydration, softening the stool, and stimulating peristalsis to facilitate evacuation.

The appropriate dose of Laxolen is determined by the prescribing healthcare professional based on the patient’s condition, severity of constipation, and individual response. Patients should follow the prescriber’s instructions and not self‑adjust the dose.

Safety data for Laxolen in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Laxolen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Laxolen combines an osmotic agent (sodium citrate) with a surfactant (sodium lauryl sulfoacetate), offering both water‑drawing and stool‑softening actions. Compared with simple osmotic laxatives, it may provide faster relief, while avoiding the stimulant effects of agents like bisacodyl.

Store Laxolen at ambient temperature, below 25 °C, in its original packaging. Protect it from moisture, excessive heat and direct sunlight to maintain product stability.

Laxolen is administered rectally. The prescribed amount is inserted into the rectum, typically using a suitable applicator, and retained for the period advised by the prescriber to allow the active ingredients to act locally.

Serious risks include severe electrolyte disturbances such as hyponatremia and persistent abdominal pain that may indicate an underlying condition. Patients experiencing these symptoms should seek immediate medical attention.

Laxolen should be avoided in individuals with known hypersensitivity to sodium citrate, sodium lauryl sulfoacetate, or any excipients, as well as in patients with intestinal obstruction, severe inflammatory bowel disease, or uncontrolled electrolyte imbalances unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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