Product image of Lbuprofen Sameko (Ibuprofen) supplied by GNH India

Lbuprofen Sameko

Active Ingredient:
Ibuprofen
Origin:
EU

Lbuprofen Sameko (Ibuprofen)

Ibuprofen, the active ingredient in Lbuprofen Sameko, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults.

GNH India supplies Lbuprofen Sameko as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sameko Farma B.V.

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Indications & Clinical Uses

Ibuprofen, an NSAID, reduces pain and inflammation by inhibiting cyclooxygenase enzymes.

  • Headache: provides relief from mild to moderate headache pain.
  • Fever: lowers elevated body temperature.
  • Arthritis: decreases joint inflammation and associated discomfort.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or itching.
  • Headache: occasional mild headache.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment, especially in volume‑depleted patients.
  • Severe allergic reactions such as anaphylaxis or angioedema.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding.
  • Monitor renal function: especially in patients with kidney disease or dehydration.
  • Avoid in late pregnancy: contraindicated during the third trimester.
  • Use lowest effective dose: limit duration to reduce adverse events.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Aspirin: increased risk of gastrointestinal bleeding.
  • Anticoagulants (warfarin, DOACs): heightened bleeding tendency.
  • Selective COX‑2 inhibitors: additive renal toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal function when combined.
  • Diuretics: risk of renal impairment and electrolyte imbalance.
  • Lithium: ibuprofen can raise serum lithium concentrations.

Frequently Asked Questions

Lbuprofen Sameko contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as osteoarthritis and rheumatoid arthritis. It is appropriate for adult patients who need short‑term symptom control.

Ibuprofen works by blocking the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signals, and helps lower elevated body temperature.

The specific dose and dosing schedule for Lbuprofen Sameko are determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Ibuprofen is generally avoided in the third trimester of pregnancy because it may affect fetal cardiovascular function. Use during earlier pregnancy or while breastfeeding should only be considered if the prescriber determines that the benefits outweigh potential risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen offers a balanced profile of analgesic, antipyretic and anti‑inflammatory effects with a relatively short half‑life, allowing flexible dosing. Compared with stronger NSAIDs such as diclofenac or naproxen, ibuprofen may have a lower risk of certain cardiovascular events but similar gastrointestinal cautions.

Store Lbuprofen Sameko at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and excessive heat to maintain stability.

Lbuprofen Sameko is intended for oral administration. The tablet or capsule should be swallowed whole with a full glass of water, preferably with food or milk to lessen gastrointestinal irritation.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, and severe allergic reactions such as anaphylaxis. Patients with a history of ulcers, renal impairment, or cardiovascular disease should be monitored closely.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe renal or hepatic impairment, and pregnant women in the third trimester should avoid using Lbuprofen Sameko unless directed otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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