Product image of Leachim (Travoprost) supplied by GNH India

Leachim

Active Ingredient:
Travoprost
Origin:
EU

Leachim (Travoprost)

Travoprost, the active ingredient in Leachim, is a prostaglandin analog presented as an unknown/unknown for ocular use. It treats open-angle glaucoma and ocular hypertension in adult patients by lowering intra‑ocular pressure.
GNH India supplies Leachim as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aet, De

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Indications & Clinical Uses

Travoprost is a prostaglandin analog used to manage conditions that involve elevated intra‑ocular pressure.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent development of glaucoma.

How It Works

  • Travoprost acts as a selective prostaglandin F2α (FP) receptor agonist in the eye. Activation of FP receptors enhances uveoscleral outflow of aqueous humor, thereby decreasing intra‑ocular pressure. The increased outflow improves fluid drainage without affecting production, providing sustained pressure control in glaucomatous eyes.

Side Effects

Travoprost may cause a range of ocular and systemic reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Eye irritation or foreign‑body sensation.
  • Blurred vision: temporary visual disturbance after instillation.
  • Increased eyelash growth (hypertrichosis).
  • Darkening of the iris or peri‑ocular skin.
  • Eye pain or discomfort.

Serious or Rare Side Effects

  • Uveitis or severe intra‑ocular inflammation.
  • Cystoid macular edema, especially in patients with risk factors.
  • Allergic reactions such as eyelid swelling or rash.
  • Vision loss due to uncontrolled pressure spikes.
  • Corneal epithelial defects.
  • Severe ocular infection.

Precautions & Warnings

Before prescribing Travoprost, clinicians should consider several safety aspects.

  • Monitor intra‑ocular pressure: ensure target pressure is achieved and maintained.
  • Assess for ocular infection or inflammation: avoid use in active conjunctivitis or keratitis.
  • Caution in patients with a history of herpetic eye disease: may trigger reactivation.
  • Avoid concurrent use with other prostaglandin analog eye drops: risk of excessive pressure reduction.
  • Evaluate for hypersensitivity to any component of the formulation.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Travoprost can interact with other ophthalmic agents and systemic medications.

Major Interactions (Avoid)

  • Concurrent use of multiple intra‑ocular pressure‑lowering eye drops (e.g., other prostaglandin analogs) may cause excessive pressure reduction.
  • Co‑administration with ocular corticosteroids may diminish Travoprost efficacy.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops may have additive IOP‑lowering effects; monitor pressure closely.
  • Alpha‑agonist or carbonic anhydrase inhibitor eye drops may increase overall pressure‑lowering effect.
  • Systemic antihistamines or anticholinergics may exacerbate dry‑eye symptoms.

Frequently Asked Questions

Leachim contains travoprost, a prostaglandin analog indicated for the treatment of open‑angle glaucoma and ocular hypertension. By lowering intra‑ocular pressure, it helps to prevent optic nerve damage and preserve visual field in patients with these conditions.

Travoprost binds to prostaglandin F2α (FP) receptors in the eye, stimulating the uveoscleral outflow pathway. This increased drainage of aqueous humor reduces intra‑ocular pressure, which is the primary therapeutic goal in glaucoma and ocular hypertension management.

The prescribed dose of travoprost is determined by the treating ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact regimen should follow the clinician’s instructions and the product label.

Safety data for travoprost in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order Leachim, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Travoprost and latanoprost belong to the same prostaglandin analog class and share a similar mechanism of increasing uveoscleral outflow. Clinical studies show comparable efficacy in lowering intra‑ocular pressure, though individual patient response and tolerability may differ, making physician selection based on patient‑specific factors.

Leachim should be stored at room temperature, below 25 °C, in its original packaging. Protect the bottle from moisture and direct sunlight. Do not freeze the product, and keep the dropper tip clean to avoid contamination.

Leachim is administered as an ocular drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a pocket, and place a single drop into the conjunctival sac of the affected eye(s). Close the eye gently for a few seconds and avoid blinking excessively.

Serious risks associated with travoprost include uveitis, cystoid macular edema, severe allergic reactions, and sudden vision loss due to uncontrolled pressure spikes. Patients should report any sudden eye pain, redness, vision changes, or swelling to their eye care professional immediately.

Travoprost is contraindicated in patients with known hypersensitivity to travoprost or any component of the formulation, and in eyes with active inflammation, infection, or severe ocular surface disease. Caution is also advised for individuals with a history of herpetic eye disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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