Product image of Leachim (Travoprost) supplied by GNH India

Leachim

Active Ingredient:
Travoprost
Origin:
EU

Leachim (Travoprost)

Travoprost, the active ingredient in Leachim, is a prostaglandin analog presented as a eye drops for ocular use. It treats open‑angle glaucoma and ocular hypertension in adults by lowering intraocular pressure.

GNH India supplies Leachim as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aet, De

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Indications & Clinical Uses

Travoprost is a prostaglandin analog used to lower intraocular pressure in glaucoma and ocular hypertension.

  • Open-angle glaucoma: reduces intraocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent conversion to glaucoma.
  • Elevated intraocular pressure: assists in managing pressure when monotherapy is insufficient.

How It Works

  • Travoprost binds to prostaglandin F (FP) receptors on the ciliary muscle, activating the phosphatidylinositol‑calcium pathway. This increases uveoscleral outflow of aqueous humor, thereby reducing intraocular pressure. The effect is sustained with once‑daily ocular administration, providing consistent pressure control in patients with glaucoma or ocular hypertension.

Side Effects

Travoprost may cause ocular and systemic reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Eye irritation: burning or stinging sensation.
  • Blurred vision: transient visual disturbance.
  • Increased eyelash growth: longer, thicker lashes.
  • Darkening of iris: gradual pigmentation change.
  • Eye pain: mild discomfort after instillation.

Serious or Rare Side Effects

  • Uveitis: inflammation of the uveal tract.
  • Macular edema: swelling of the central retina.
  • Severe allergic reaction: swelling, itching, or rash.
  • Vision loss: sudden decrease in visual acuity.
  • Persistent eye pain: may indicate corneal involvement.
  • Endophthalmitis: rare intraocular infection.

Precautions & Warnings

Before prescribing Travoprost, clinicians should consider several safety measures.

  • Monitor IOP: regularly assess intraocular pressure to gauge efficacy.
  • Assess ocular surface: watch for redness, irritation, or corneal changes.
  • Avoid use in active ocular inflammation: contraindicated in uveitis or severe conjunctivitis.
  • Caution in patients with a history of uveitis: increased risk of recurrence.
  • Store at room temperature: keep bottle in original packaging, protect from light and moisture.

Avoid Interactions

Travoprost can interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent prostaglandin analog eye drops: may increase ocular adverse effects.
  • Systemic beta‑blockers: additive IOP‑lowering may cause hypotension.
  • Ocular corticosteroids: may reduce Travoprost efficacy.

Moderate Interactions (Monitor Closely)

  • Alpha‑agonist eye drops: may affect overall IOP control.
  • Topical anesthetics: may increase corneal toxicity risk.
  • Contact lens wear: may cause discomfort or reduced drug absorption.

Frequently Asked Questions

Leachim contains travoprost, a prostaglandin analog indicated for the treatment of open‑angle glaucoma and ocular hypertension. By lowering intraocular pressure, it helps prevent optic nerve damage and visual field loss associated with these conditions.

Travoprost activates prostaglandin F (FP) receptors in the eye, stimulating the uveoscleral pathway to increase outflow of aqueous humor. This enhanced drainage reduces intraocular pressure, which is the primary therapeutic goal in glaucoma and ocular hypertension.

The prescribed dose is determined by the treating ophthalmologist. Typically, one drop of Leachim is instilled into the affected eye(s) once daily in the evening, but the exact regimen should follow the clinician’s instructions.

Safety data for travoprost in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. It should only be used if the potential benefit justifies any possible risk to the fetus or infant.

To order Leachim, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Leachim (travoprost) belongs to the prostaglandin analog class, similar to latanoprost and bimatoprost. All three lower intraocular pressure by increasing uveoscleral outflow, but individual response, side‑effect profiles, and tolerability may differ, making clinician selection based on patient-specific factors.

Leachim eye drops should be stored at room temperature, below 25 °C, in the original container. Protect the bottle from direct sunlight and moisture, and keep the cap tightly closed when not in use to maintain sterility.

Instill one drop of Leachim into the conjunctival sac of the prescribed eye(s) once daily, preferably in the evening. Tilt the head back, pull down the lower eyelid to create a small pocket, and avoid touching the tip of the bottle to the eye or any surface.

Serious adverse events, though rare, include uveitis, macular edema, severe allergic reactions, and sudden vision loss. Patients should seek immediate medical attention if they experience persistent eye pain, significant visual changes, or signs of intraocular inflammation.

Leachim is contraindicated in patients with known hypersensitivity to travoprost or any component of the formulation, and in those with active ocular inflammation such as uveitis or severe conjunctivitis. Caution is also advised for individuals with a history of ocular infections.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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