Product image of Lecalcif (Colecalciferol) supplied by GNH India

Lecalcif

Active Ingredient:
Colecalciferol
Origin:
EU

Lecalcif (Colecalciferol)

Colecalciferol, the active ingredient in Lecalcif, is a vitamin D presented as an oral supplement for oral use. It is used to correct vitamin D deficiency and to support bone health in individuals at risk of osteomalacia or rickets, especially in populations with limited sun exposure.

GNH India supplies Lecalcif as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution for this vitamin D product.

Manufacturer / TM Owner

Rafarm Sa.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lecalcif (colecalciferol) is used to address disorders related to insufficient vitamin D activity.

  • Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D levels, improving calcium balance.
  • Osteomalacia and rickets prevention: supports bone mineralization to prevent softening of bones in adults and children.
  • General bone health support: contributes to maintaining bone density and reducing fracture risk in at‑risk individuals.

How It Works

  • Colecalciferol is metabolized in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone 1,25‑dihydroxyvitamin D (calcitriol). The active form binds to the vitamin D receptor (VDR) in target cells, modulating gene transcription that enhances intestinal absorption of calcium and phosphate, thereby promoting bone mineralization and calcium homeostasis.

Side Effects

Oral colecalciferol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Hypercalcemia: mild elevation of blood calcium causing fatigue or nausea.
  • Nausea: occasional stomach upset after taking the supplement.
  • Headache: transient mild headache episodes.

Serious or Rare Side Effects

  • Severe hypercalcemia: may result in cardiac arrhythmia or renal dysfunction.
  • Kidney stones: formation of calcium deposits in the urinary tract.
  • Allergic reactions: rash, itching, swelling, or rare anaphylaxis.

Precautions & Warnings

When using Lecalcif, consider the following precautions to ensure safe and effective therapy.

  • Serum calcium monitoring: check calcium levels before and during therapy in patients at risk of hypercalcemia.
  • Renal impairment caution: adjust dose or avoid use in severe kidney disease.
  • High calcium intake: avoid excessive dietary calcium or calcium supplements concurrently.
  • Granulomatous disease awareness: conditions such as sarcoidosis may increase sensitivity to vitamin D.
  • Pregnancy and lactation: use only if prescribed after risk‑benefit assessment.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

Avoid Interactions

Colecalciferol may interact with certain medicines; the following interactions are recognized.

Major Interactions (Avoid)

  • Thiazide diuretics: can increase risk of hypercalcemia.
  • High‑dose calcium supplements: may cause excessive calcium accumulation.
  • Vitamin A excess: combined toxicity leading to hypercalcemia.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may reduce vitamin D effectiveness, requiring dose adjustment.
  • Anticonvulsants (e.g., phenytoin, carbamazepine): increase vitamin D metabolism, potentially lowering levels.
  • Cholesterol‑lowering agents (e.g., cholestyramine): may impair absorption of fat‑soluble vitamins.

Frequently Asked Questions

Lecalcif is an oral vitamin D supplement containing colecalciferol. It is used to correct vitamin D deficiency, help prevent osteomalacia and rickets, and support overall bone health in individuals who need additional vitamin D to maintain proper calcium metabolism.

Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone 1,25‑dihydroxyvitamin D. This active form binds to vitamin D receptors in various tissues, stimulating the absorption of calcium and phosphate from the gut and promoting bone mineralization.

The appropriate dose of Lecalcif is individualized by a healthcare professional based on factors such as the patient’s serum vitamin D level, age, underlying health conditions, and concurrent medications. The prescriber sets the dosage and duration according to clinical guidelines and the patient’s specific needs.

Safety of lecacif (colecalciferol) in pregnancy or lactation should be evaluated by a qualified clinician. Vitamin D is essential for fetal bone development, but dosing must be appropriate. Pregnant or nursing individuals should only use the product if prescribed after a risk‑benefit assessment.

To order Lecalcif, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lecalcif contains colecalciferol, the same form of vitamin D3 found in many over‑the‑counter supplements. Its quality is ensured by GNH India’s GMP‑compliant manufacturing and EU market approval. Compared with some alternatives that may use vitamin D2 (ergocalciferol), colecalciferol generally offers better bioavailability and longer duration of action.

Lecalcif should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Lecalcif is taken orally, usually with or without food, as directed by a healthcare professional. The tablet or capsule is swallowed whole with a glass of water. Patients should follow the prescriber’s instructions regarding timing and any specific dietary considerations.

The most serious risks involve excessive vitamin D levels leading to severe hypercalcemia, which can cause cardiac arrhythmias, renal impairment, or kidney stone formation. Rarely, allergic reactions such as rash, swelling, or anaphylaxis may occur. Monitoring calcium levels and adhering to prescribed doses help mitigate these risks.

Individuals with known hypersensitivity to colecalciferol or any excipients in the formulation should avoid Lecalcif. Patients with uncontrolled hypercalcemia, severe renal disease, or granulomatous disorders such as sarcoidosis should consult a physician before use, as they may be at higher risk for adverse effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.