Product image of Lecicarbon (Sodium Hydrogen Carbonate, Sodium Dihydrogen Phosphate) supplied by GNH India

Lecicarbon

Active Ingredient:
Sodium Hydrogen Carbonate, Sodium Dihydrogen Phosphate
Origin:
EU

Lecicarbon (Sodium Hydrogen Carbonate, Sodium Dihydrogen Phosphate)

Sodium hydrogen carbonate, the active ingredient in Lecicarbon, is a buffering agent presented as a rectal formulation for rectal use. It helps neutralize acids and supplies bicarbonate and phosphate ions to maintain local pH balance.\n\nGNH India supplies Lecicarbon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Athenstaedt Gmbh & Co Kg

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Indications & Clinical Uses

  • Lecicarbon, a rectal buffering preparation, is employed in clinical situations where local acid neutralization is desired.\n\n- Rectal acid neutralization: assists in correcting local pH disturbances in the rectal mucosa.\n- Adjunct in bowel preparation: contributes to a neutral environment before diagnostic or surgical procedures.\n- Support in systemic acid‑base management: provides bicarbonate and phosphate ions via the rectal route to aid overall acid‑base balance.

How It Works

  • Lecicarbon delivers sodium hydrogen carbonate and sodium dihydrogen phosphate directly to the rectal mucosa, where they dissociate to release bicarbonate and phosphate ions. These ions increase the local buffering capacity, neutralizing excess hydrogen ions and helping to restore physiological pH. The released phosphate also participates in systemic phosphate pools, while sodium contributes to osmotic balance.

Side Effects

  • Common Side Effects:\n- Mild rectal irritation or burning sensation.\n- Abdominal discomfort or cramping.\n- Flatulence or bloating.\n- Nausea or mild vomiting.\n- Diarrhea or loose stools.\n- Transient electrolyte shifts (e.g., mild sodium increase).\n\nSerious or Rare Side Effects:\n- Severe electrolyte disturbances (hypernatremia, hyperphosphatemia).\n- Metabolic alkalosis.\n- Allergic reactions including rash, urticaria, or anaphylaxis.\n- Significant rectal bleeding.\n- Severe abdominal pain requiring medical evaluation.\n- Rare cases of renal impairment exacerbation.

Precautions & Warnings

  • Before using Lecicarbon, consider the following precautions.\n\n- Assess electrolyte status: monitor sodium and phosphate levels during therapy.\n- Avoid in severe renal impairment: risk of ion accumulation.\n- Use with caution in hypertension: sodium load may affect blood pressure.\n- Check for hypersensitivity: discontinue if allergic signs appear.\n- Pregnancy and lactation: limited data, evaluate risk‑benefit ratio.\n- Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

  • Lecicarbon may interact with other medications that affect electrolyte balance or acid‑base status.\n\nMajor Interactions (Avoid):\n- Concurrent oral sodium bicarbonate: risk of excessive alkalosis.\n- Intravenous phosphate solutions: additive phosphate load may cause hyperphosphatemia.\n- Potassium‑sparing diuretics: potential for electrolyte imbalance.\n\nModerate Interactions (Monitor Closely):\n- ACE inhibitors: monitor potassium levels.\n- Loop diuretics: watch for combined electrolyte shifts.\n- Other antacids or alkalinizing agents: additive effect on pH.

Frequently Asked Questions

Lecicarbon is a rectally administered buffering preparation that provides bicarbonate and phosphate ions to help neutralize excess acidity in the rectal mucosa and support overall acid‑base balance in clinical settings.

Sodium hydrogen carbonate dissociates to release bicarbonate ions, which combine with hydrogen ions to form water and carbon dioxide, thereby raising the local pH and reducing acidity. The accompanying phosphate ions also contribute to buffering capacity.

The dose of Lecicarbon is determined by the prescribing clinician based on the patient’s condition, age, renal function and electrolyte status. No fixed regimen is provided; the prescriber sets the appropriate amount.

Safety data for Lecicarbon in pregnancy and lactation are limited. Healthcare providers should weigh potential benefits against possible risks and consider alternative therapies when appropriate.

To order Lecicarbon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Lecicarbon combines both sodium bicarbonate and sodium dihydrogen phosphate, offering dual buffering action. Compared with single‑component agents, it may provide a broader pH‑stabilising effect, but clinical choice depends on the specific therapeutic goal and physician judgment.

Store Lecicarbon at room temperature, below 25 °C, in its original container. Protect it from moisture and direct sunlight to maintain stability and potency.

Lecicarbon is administered rectally, typically as an enema or suppository, according to the prescriber’s instructions. Proper technique ensures optimal distribution of the buffering solution to the rectal mucosa.

Serious risks include severe electrolyte disturbances such as hypernatremia or hyperphosphatemia, metabolic alkalosis, and rare allergic reactions that may lead to anaphylaxis. Patients should be monitored for these events, especially if they have underlying renal or cardiac conditions.

Lecicarbon should be avoided in patients with severe renal failure, uncontrolled hypertension, known hypersensitivity to its components, or those who are receiving high‑dose sodium or phosphate therapies unless directed by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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