Product image of Lecrolyn Sine (Sodium Cromoglicate) supplied by GNH India

Lecrolyn Sine

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Lecrolyn Sine (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Lecrolyn Sine, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is employed to manage allergic conjunctivitis and mast cell‑mediated ocular allergy in patients requiring topical anti‑allergic therapy.

GNH India supplies Lecrolyn Sine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Santen Oy

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lecrolyn Sine is a mast cell stabilizer used to treat ocular allergic conditions by preventing mediator release.
  • Allergic conjunctivitis: reduces itching, redness and watery discharge caused by allergens.
  • Mast cell‑mediated ocular allergy: stabilises ocular mast cells to prevent inflammation.
  • Seasonal allergic eye disease: provides relief during pollen seasons by limiting histamine release.

How It Works

  • Sodium cromoglicate binds to mast cell membranes and inhibits calcium influx, which prevents degranulation and the subsequent release of histamine, prostaglandins, and other inflammatory mediators. By stabilising mast cells, it reduces ocular inflammation and allergic symptomatology without directly blocking histamine receptors.

Side Effects

Adverse reactions are generally mild and localized to the eye.

Common Side Effects

  • Transient ocular irritation or burning sensation.
  • Stinging upon instillation.
  • Blurred vision lasting a few minutes.
  • Mild conjunctival hyperemia.
  • Foreign body sensation.
  • Temporary increased tear production.

Serious or Rare Side Effects

  • Allergic contact dermatitis of the eyelid.
  • Severe eye inflammation or keratitis.
  • Corneal ulceration.
  • Anaphylactic reaction (extremely rare).

Precautions & Warnings

  • When using Lecrolyn Sine, consider the following safety measures.
  • Avoid use with contact lenses: remove lenses before and after administration.
  • Discontinue if severe irritation occurs: seek ophthalmic evaluation.
  • Do not exceed prescribed frequency: follow prescriber instructions.
  • Keep out of reach of children: store securely.
  • Store at room temperature below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lecrolyn Sine may interact with other ophthalmic agents; monitor for combined effects.

Major Interactions (Avoid)

  • Topical ocular anesthetics: may increase ocular irritation.
  • Other mast cell stabilisers: concurrent use offers no added benefit and may increase local discomfort.

Moderate Interactions (Monitor Closely)

  • Antihistamine eye drops: may reduce the stabilising effect of sodium cromoglicate.
  • Systemic antihistamines: additive sedation is unlikely but monitor patient response.
  • Contact lens cleaning solutions: may affect drug stability; ensure lenses are removed during treatment.

Frequently Asked Questions

Lecrolyn Sine is an ophthalmic solution containing sodium cromoglicate, used to treat allergic conjunctivitis and mast cell‑mediated ocular allergy by stabilising mast cells and reducing eye inflammation.

Sodium cromoglicate binds to mast cell membranes in the ocular surface, inhibiting calcium influx and preventing degranulation. This blocks the release of histamine and other inflammatory mediators, thereby reducing allergic eye symptoms.

The dosing regimen for Lecrolyn Sine is determined by the prescribing ophthalmologist based on the severity of the allergic condition and patient response. Patients should follow the specific instructions provided by their healthcare professional.

Safety data for sodium cromoglicate in pregnancy and lactation are limited. The prescriber should evaluate the risk‑benefit profile for each individual, and the medication should only be used if clearly needed.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike antihistamine eye drops that block histamine receptors, Lecrolyn Sine stabilises mast cells, preventing the release of multiple inflammatory mediators. This broader mechanism can provide more comprehensive control of allergic eye symptoms for some patients.

Store the ophthalmic solution at room temperature below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the bottle tightly closed when not in use.

Lecrolyn Sine is applied as eye drops. The prescribed number of drops is placed into the conjunctival sac of the affected eye(s) according to the prescriber’s instructions, usually several times daily.

Serious but rare risks include allergic contact dermatitis of the eyelid, severe eye inflammation such as keratitis, corneal ulceration, and anaphylaxis. Any signs of severe ocular reaction require immediate medical attention.

Patients with known hypersensitivity to sodium cromoglicate or any component of the formulation should avoid using Lecrolyn Sine. Individuals with active severe eye infections should also defer use until cleared by an ophthalmologist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Cromoglicate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT