Product image of Lecrolyn (Sodium Cromoglicate) supplied by GNH India

Lecrolyn

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Lecrolyn (Sodium Cromoglicate)

Sodium Cromoglicate, the active ingredient in Lecrolyn, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is indicated for patients experiencing seasonal or perennial eye allergy symptoms and is formulated for convenient drop administration. It is employed to manage allergic conjunctivitis and related ocular itching in patients requiring topical antiallergic therapy.

GNH India supplies Lecrolyn as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

  • Lecrolyn, a mast cell stabilizer, is used to treat ocular allergic conditions by preventing mediator release.
  • Allergic conjunctivitis: reduces redness, swelling and itching associated with allergic eye inflammation.
  • Ocular itching due to allergy: provides rapid relief of itch sensation in the eyes.
  • Seasonal allergic conjunctivitis: controls symptoms during pollen seasons by stabilizing ocular mast cells.

How It Works

  • Sodium Cromoglicate acts by binding to calcium channels on mast cells in the conjunctival and corneal tissues, inhibiting calcium influx that triggers degranulation. By stabilizing the mast cell membrane, it prevents the release of histamine, prostaglandins and other inflammatory mediators, thereby reducing the allergic cascade that leads to ocular redness, swelling and itching. The effect is localized to the ocular surface, with minimal systemic absorption.

Side Effects

Topical ocular administration of Lecrolyn may be associated with the following adverse reactions.

Common Side Effects

  • Burning or stinging sensation upon instillation.
  • Transient blurred vision or mild eye irritation.
  • Temporary increase in tear production.

Serious or Rare Side Effects

  • Allergic contact dermatitis of the eyelid or conjunctiva.
  • Corneal ulcer or severe keratitis.
  • Sudden loss of vision or severe eye pain requiring immediate medical attention.

Precautions & Warnings

  • When using Lecrolyn, consider the following precautions to ensure safe and effective therapy.
  • Hypersensitivity: Do not use if known allergy to sodium cromoglicate or any excipients.
  • Contact lenses: Remove contact lenses before instillation and wait at least 15 minutes before reinserting.
  • Concurrent ocular infection: Avoid use in the presence of active bacterial, viral or fungal eye infection unless directed by a clinician.
  • Pregnancy and lactation: Use only if the benefit outweighs potential risk, as safety data are limited.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lecrolyn may interact with other ophthalmic or systemic agents; the following interactions have been reported.

Major Interactions (Avoid)

  • Concurrent use with topical ocular anesthetics may increase corneal toxicity.

Moderate Interactions (Monitor Closely)

  • Use with other mast cell stabilizer eye drops may increase local irritation.
  • Combination with topical corticosteroids may raise risk of ocular infection.
  • Co‑administration with antihistamine eye drops may reduce the efficacy of either agent.
  • Systemic antihistamines may have additive antiallergic effect, requiring monitoring.

Frequently Asked Questions

Lecrolyn is an ophthalmic solution containing sodium cromoglicate that is used to treat allergic eye conditions such as allergic conjunctivitis and ocular itching caused by environmental allergens. It works locally on the eye surface to reduce inflammation, redness and itching associated with these allergic responses.

Sodium cromoglicate stabilizes mast cells in the conjunctiva and cornea by blocking calcium influx, which prevents the cells from releasing histamine and other inflammatory mediators. By inhibiting this degranulation process, the drug reduces the cascade of allergic inflammation that leads to eye redness, swelling and itching.

The dosing regimen for Lecrolyn is determined by the prescribing clinician based on the severity of the allergic eye condition and patient response. Typically, one or two drops are instilled into the affected eye(s) as directed, but the exact frequency and duration should follow the healthcare professional’s instructions.

Safety data for sodium cromoglicate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision should be made in consultation with a qualified healthcare provider.

To order Lecrolyn, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Lecrolyn (sodium cromoglicate) is a mast cell stabilizer, whereas many alternative eye allergy drops are antihistamines or combination antihistamine‑mast cell stabilizers. Sodium cromoglicate primarily prevents mediator release, offering a prophylactic effect, while antihistamines provide rapid symptom relief. Choice of therapy depends on patient preference, severity of symptoms and clinician assessment.

Lecrolyn should be stored at room temperature, away from direct sunlight and moisture. Keep the vial in its original packaging until use, and avoid freezing. If the solution becomes cloudy or discolored, discard it and obtain a new supply.

Lecrolyn is administered as an eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid to create a small pocket, and place the prescribed number of drops into the conjunctival sac. Contact lenses should be removed before instillation and re‑inserted after a suitable waiting period.

Although uncommon, serious adverse reactions can include allergic contact dermatitis of the eyelid or conjunctiva, corneal ulceration or severe keratitis, and sudden loss of vision or intense eye pain. Any of these symptoms require immediate medical evaluation and discontinuation of the product.

Lecrolyn should not be used by individuals with a known hypersensitivity to sodium cromoglicate or any of its excipients. It is also contraindicated in the presence of active ocular infections unless specifically directed by a healthcare professional, and caution is advised in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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