Product image of Lecrolyn (Sodium Cromoglicate) supplied by GNH India

Lecrolyn

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Lecrolyn (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Lecrolyn, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is approved in the European Union for the management of allergic conjunctivitis and ocular itching due to allergy, providing relief for patients who require prescription therapy.

GNH India supplies Lecrolyn as a licensed, GDP‑compliant international pharmaceutical supplier, delivering the product to hospitals, pharmacies and clinics worldwide under strict quality‑assured conditions. The company adheres to EU GMP standards and supports global procurement for eye care specialists.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

  • Sodium cromoglicate (Lecrolyn) is used to manage allergic eye conditions by stabilising mast cells.
  • Allergic conjunctivitis: reduces ocular redness, swelling and itching associated with allergic reactions.
  • Ocular itching due to allergy: relieves itching and discomfort in the eyes caused by allergens.
  • Seasonal allergic conjunctivitis: controls symptoms during pollen or seasonal allergen exposure.

How It Works

  • Sodium cromoglicate stabilises mast cells in the conjunctival tissue, preventing degranulation and the subsequent release of histamine, leukotrienes and other inflammatory mediators. By inhibiting this cascade, it reduces vascular permeability, edema and the sensory nerve activation that cause redness, swelling and itching in allergic eye disease.

Side Effects

Adverse reactions are generally mild and transient.

Common Side Effects

  • Burning or stinging sensation on instillation.
  • Temporary blurred vision.
  • Mild eye irritation or foreign‑body sensation.
  • Conjunctival hyperemia.
  • Tearing or increased lacrimation.
  • Mild headache.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with swelling of the eyelids or face.
  • Persistent or worsening eye inflammation.
  • Corneal ulceration or keratitis.
  • Vision loss or significant visual disturbance.
  • Secondary ocular infection.
  • Persistent ocular pain.

Precautions & Warnings

  • Before using Lecrolyn, consider the following safety measures.
  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: unknown; weigh potential benefits against risks.
  • Contact lens wearers: remove lenses before instillation and wait at least 15 minutes before reinserting.
  • Concomitant ocular medications: administer other drops at least five minutes apart to avoid dilution.
  • Allergy to sodium cromoglicate: contraindicated.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Lecrolyn may interact with other ophthalmic agents; monitor patients accordingly.

Major Interactions (Avoid)

  • Concurrent use with ophthalmic anesthetics may increase corneal toxicity.
  • Systemic mast cell stabilisers may produce additive effects and are not recommended.
  • Topical corticosteroids can mask signs of infection when used together.

Moderate Interactions (Monitor Closely)

  • Antihistamine eye drops may reduce the efficacy of sodium cromoglicate.
  • Non‑steroidal anti‑inflammatory eye drops can increase ocular irritation when combined.
  • Preservative‑containing solutions may exacerbate local sensitivity.

Frequently Asked Questions

Lecrolyn contains sodium cromoglicate and is prescribed to treat allergic conjunctivitis and ocular itching caused by allergy. It works by stabilising mast cells in the eye, helping to reduce redness, swelling and discomfort associated with allergic eye disease.

Sodium cromoglicate prevents mast cells in the conjunctiva from releasing histamine and other inflammatory mediators. By blocking this release, it limits the cascade that leads to vascular leakage, edema and nerve irritation, thereby alleviating the symptoms of allergic eye inflammation.

The dosing regimen for Lecrolyn is determined by the prescribing clinician based on the severity of the allergic eye condition and patient response. The prescriber will specify the number of drops, frequency and duration of treatment.

Safety data for sodium cromoglicate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To request Lecrolyn, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lecrolyn (sodium cromoglicate) is a mast cell stabiliser, whereas many other anti‑allergic eye drops are antihistamines or combination products. Mast cell stabilisers act upstream by preventing mediator release, offering a prophylactic approach, while antihistamines provide rapid symptom relief after exposure.

Lecrolyn should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from direct light and moisture, and discard any solution that appears discoloured or cloudy.

Lecrolyn is an ophthalmic solution applied as eye drops. The patient instils the prescribed number of drops into the affected eye(s) using a clean fingertip to lower the bottle, avoiding contact with the ocular surface, and follows any interval recommendations for other eye medications.

Although rare, serious adverse events can include severe allergic reactions such as anaphylaxis, persistent eye inflammation, corneal ulceration, or significant visual disturbances. Patients should seek immediate medical attention if they experience sudden swelling, pain, vision loss or signs of infection.

Lecrolyn is contraindicated in individuals with a known hypersensitivity to sodium cromoglicate or any component of the formulation. It should also be avoided in patients who cannot safely discontinue contact lens use during treatment or who have active severe ocular infections.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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