Product image of Lecrolyn (Sodium Cromoglicate) supplied by GNH India

Lecrolyn

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Lecrolyn (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Lecrolyn, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is employed to manage allergic conjunctivitis and seasonal ocular allergy by reducing histamine release in the eyes of affected patients.

GNH India supplies Lecrolyn as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent product availability and regulatory compliance across EU and other markets.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

  • Lecrolyn, a mast cell stabilizer, is used to treat ocular allergic conditions by preventing mediator release.
  • Allergic conjunctivitis: reduces eye redness, itching and tearing caused by allergen exposure.
  • Seasonal ocular allergy: alleviates symptoms during pollen seasons by stabilizing ocular mast cells.
  • Mast cell‑mediated eye inflammation: helps control inflammation in various allergic eye disorders.

How It Works

  • Sodium cromoglicate stabilizes ocular mast cells, inhibiting calcium‑dependent degranulation and preventing the release of histamine, leukotrienes, and other inflammatory mediators. By blocking this cascade, it reduces vascular permeability, edema, and sensory nerve activation that contribute to allergic eye symptoms.

Side Effects

Lecrolyn may cause local ocular reactions.

Common Side Effects

  • Transient eye irritation or burning sensation.
  • Stinging or mild discomfort upon instillation.
  • Blurred vision lasting a few minutes.
  • Mild conjunctival hyperemia.
  • Foreign body sensation.
  • Temporary increased tear production.

Serious or Rare Side Effects

  • Allergic reaction with swelling of the eyelid or periorbital area.
  • Severe eye pain or photophobia.
  • Vision loss or sudden visual disturbance.
  • Corneal ulceration or epithelial defect.
  • Persistent redness unresponsive to treatment.

Precautions & Warnings

  • Before using Lecrolyn, consider the following precautions.
  • Assess patient history for active ocular infections: avoid use if infection is present.
  • Avoid in patients with known hypersensitivity to sodium cromoglicate or formulation excipients.
  • Do not wear contact lenses immediately after instillation unless advised by a clinician.
  • Monitor for worsening symptoms: discontinue and seek medical advice if condition deteriorates.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Lecrolyn has a low potential for drug interactions, but certain combinations warrant attention.

Major Interactions (Avoid)

  • Concurrent use with ocular anesthetics may increase risk of corneal toxicity.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids may elevate intraocular pressure when used together.
  • Contact lens solutions can affect drug stability; verify compatibility.
  • Other ophthalmic antibiotics may cause additive ocular irritation.
  • Systemic antihistamines may reduce overall allergic response, potentially altering perceived efficacy.

Frequently Asked Questions

Lecrolyn is an ophthalmic preparation containing sodium cromoglicate that is prescribed to treat allergic conjunctivitis and seasonal ocular allergy. It works by stabilizing mast cells in the eye, thereby reducing itching, redness, tearing, and swelling associated with allergic eye disease.

Sodium cromoglicate acts as a mast cell stabilizer. It prevents calcium‑dependent degranulation of mast cells in the conjunctiva, which blocks the release of histamine, leukotrienes, and other inflammatory mediators. This inhibition reduces vascular leakage and nerve irritation, alleviating allergic eye symptoms.

The specific dosing regimen for Lecrolyn is determined by the prescribing clinician. Typically, one drop is instilled in each affected eye two to four times daily, but the exact frequency and duration depend on the severity of the allergy and the patient’s response.

Safety data for sodium cromoglicate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers should evaluate each case individually and discuss alternatives when appropriate.

To place an order, submit an enquiry on the Lecrolyn product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lecrolyn belongs to the mast cell stabilizer class, whereas many eye allergy drops are antihistamines. Mast cell stabilizers prevent the release of allergic mediators, offering a prophylactic effect, while antihistamines provide rapid symptom relief. In some cases, clinicians combine both types for optimal control.

Lecrolyn should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed in its original packaging. Do not freeze the product, and discard any solution that appears discolored or contains particles.

Lecrolyn is applied topically to the eye. After washing hands, tilt the head back, pull down the lower eyelid, and place one drop into the conjunctival sac. Close the eye gently for a few seconds, avoid blinking excessively, and refrain from touching the dropper tip to any surface.

Although rare, serious adverse events can include severe allergic reactions such as eyelid swelling, significant eye pain, sudden vision changes, or corneal ulceration. Patients experiencing any of these symptoms should discontinue use immediately and seek urgent ophthalmologic evaluation.

Lecrolyn is contraindicated in individuals with a known hypersensitivity to sodium cromoglicate or any excipients in the formulation. It should also be avoided in eyes with active infection, severe inflammation of unknown cause, or in patients who have had a recent ocular surgery unless directed by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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