Product image of Lecrolyn (Sodium Cromoglicate) supplied by GNH India

Lecrolyn

Active Ingredient:
Sodium Cromoglicate
Origin:
EU

Lecrolyn (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Lecrolyn, is a mast cell stabilizer presented as an ocular solution for ocular use. It is indicated for the treatment of allergic conjunctivitis and helps reduce eye irritation in affected individuals.

GNH India supplies Lecrolyn as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution for regulated prescription products. Clients benefit from comprehensive regulatory support and timely delivery across multiple regions.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

Lecrolyn, a mast cell stabilizer, is used to manage ocular allergic conditions by preventing mediator release.

  • Allergic conjunctivitis: reduces itching, redness and tearing associated with allergic eye inflammation.
  • Seasonal allergic conjunctivitis: provides relief during pollen seasons by stabilizing ocular mast cells.
  • Allergic eye irritation: alleviates discomfort caused by environmental allergens in the eye.

How It Works

  • Sodium cromoglicate stabilizes mast cells by inhibiting calcium influx, which prevents degranulation and the subsequent release of histamine, leukotrienes and other inflammatory mediators. By limiting these mediators in the conjunctival tissue, the drug reduces vascular permeability, edema and the sensory nerve activation that cause ocular allergy symptoms.

Side Effects

Lecrolyn is generally well tolerated, but ocular preparations can cause local reactions.

Common Side Effects

  • Transient eye irritation or burning sensation.
  • Blurred vision shortly after instillation.
  • Mild foreign‑body feeling in the eye.
  • Increased tearing or watery discharge.
  • Mild headache.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) affecting the eye.
  • Ocular edema or swelling.
  • Corneal ulceration or epithelial defect.
  • Sudden loss of vision.
  • Persistent severe pain in the eye.

Precautions & Warnings

Before using Lecrolyn, consider the following precautions.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: unknown safety; weigh potential risks against benefits.
  • Contact lens wearers: remove lenses before instilling drops and wait several minutes before reinserting.
  • Concurrent ocular infection: avoid use until infection has resolved.
  • Store at room temperature below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Lecrolyn may interact with other ophthalmic agents; monitor use accordingly.

Major Interactions (Avoid)

  • Co‑administration with ocular anesthetic drops may increase irritation.

Moderate Interactions (Monitor Closely)

  • Use with other topical ocular drugs may require spacing of administration times.
  • Use with preservative‑containing eye drops can add to local irritation.
  • Use with contact lens solutions may cause lens discoloration.
  • Use with systemic corticosteroids should be monitored for overlapping immunomodulatory effects.

Frequently Asked Questions

Lecrolyn is an ophthalmic solution that contains sodium cromoglicate, a mast cell stabilizer. It is prescribed to treat allergic conjunctivitis, helping to relieve eye itching, redness, and tearing caused by allergic reactions.

Sodium cromoglicate works by stabilizing mast cells in the conjunctiva, preventing them from releasing histamine and other inflammatory mediators. This inhibition reduces the vascular and nerve responses that produce the typical symptoms of ocular allergy.

The dosing regimen for Lecrolyn is determined by the prescribing clinician based on the severity of the allergic condition and patient response. The prescriber will specify the number of drops and frequency appropriate for each individual.

Safety data for sodium cromoglicate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To order Lecrolyn, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Lecrolyn (sodium cromoglicate) stabilizes mast cells, whereas many alternative eye drops, such as antihistamines, block histamine receptors. Mast cell stabilizers can provide prophylactic control of symptoms, while antihistamines often act more quickly on existing symptoms. Choice depends on clinical judgment and patient needs.

Lecrolyn should be stored at room temperature below 25 °C, in its original container, protected from light and moisture. Do not freeze the solution. Keep the vial tightly closed when not in use and discard any product that appears discolored or contaminated.

Lecrolyn is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. Close the eye gently for a few seconds and avoid blinking excessively.

While rare, serious adverse events can include severe allergic reactions such as anaphylaxis, ocular edema, corneal ulceration, and sudden loss of vision. Any sudden or worsening eye symptoms should prompt immediate medical evaluation.

Lecrolyn should be avoided in individuals with known hypersensitivity to sodium cromoglicate or any component of the formulation. Patients with active ocular infections should defer use until the infection is resolved, and contact lens wearers should follow proper lens removal procedures before instillation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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