Product image of Legofer (Iron Protein Succinylate) supplied by GNH India

Legofer

Active Ingredient:
Iron Protein Succinylate
Origin:
EU

Legofer (Iron Protein Succinylate)

Iron Protein Succinylate, the active ingredient in Legofer, is an iron supplement presented as an oral formulation for oral use. It is employed to treat iron deficiency anemia and other iron deficiency states in patients requiring increased iron intake.
GNH India supplies Legofer as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Elpen Pharmaceutical Co. Inc.

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Indications & Clinical Uses

  • Legofer is an oral iron supplement used to address conditions related to insufficient iron levels.
  • Iron deficiency anemia: helps restore normal hemoglobin concentrations and improve red blood cell production.
  • Iron deficiency: supports replenishment of depleted iron stores in the body.
  • Chronic blood loss: assists in correcting iron loss associated with ongoing gastrointestinal or menstrual bleeding.

How It Works

  • Iron Protein Succinylate provides bioavailable elemental iron that is absorbed in the duodenum and proximal jejunum. The absorbed iron is incorporated into hemoglobin and other iron‑dependent enzymes, facilitating oxygen transport and cellular metabolic processes essential for erythropoiesis and overall physiological function.

Side Effects

Legofer may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Constipation: reduced bowel movements.
  • Abdominal discomfort: cramping or pain.
  • Darkened stools: harmless change in stool color.
  • Metallic taste: transient alteration in taste perception.
  • Diarrhea: occasional loose stools.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Anaphylaxis: rapid onset of life‑threatening symptoms.
  • Iron overload: excessive iron accumulation with prolonged high dosing.
  • Severe abdominal pain: persistent or worsening pain.
  • Hypotension: unusually low blood pressure.

Precautions & Warnings

  • Before initiating therapy with Legofer, consider the following precautions.
  • Assess iron status: confirm deficiency through laboratory testing.
  • Monitor therapy: regularly check hemoglobin and ferritin levels.
  • Avoid hypersensitivity: discontinue if allergic reactions occur.
  • Use cautiously in gastrointestinal disease: patients with IBD may experience increased irritation.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Legofer can interact with several medications, affecting absorption or efficacy.

Major Interactions (Avoid)

  • Tetracycline antibiotics: chelation reduces absorption of both agents.
  • Levothyroxine: iron may impair thyroid hormone uptake.
  • Bisphosphonates: concurrent use diminishes absorption of each.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: may decrease iron absorption.
  • Proton pump inhibitors: reduce gastric acidity, limiting iron uptake.
  • Calcium supplements: compete for intestinal transport mechanisms.
  • Vitamin C: can increase iron absorption, potentially leading to excess.

Frequently Asked Questions

Legofer is an oral iron supplement indicated for the treatment of iron deficiency anemia and other conditions where the body lacks sufficient iron. It helps restore normal hemoglobin levels and replenish iron stores, supporting healthy red blood cell production and overall metabolic function.

Iron Protein Succinylate delivers elemental iron that is readily absorbed in the upper small intestine. Once absorbed, the iron is incorporated into hemoglobin and iron‑dependent enzymes, facilitating oxygen transport in the blood and supporting cellular processes essential for erythropoiesis and energy metabolism.

The appropriate dose of Legofer is determined by a qualified prescriber based on the patient’s iron deficiency severity, age, weight, and overall health status. Healthcare professionals tailor the regimen to achieve optimal correction of iron levels while minimizing potential side effects.

Safety data for Legofer in pregnancy and lactation are limited. Healthcare providers should evaluate the risk‑benefit profile for each individual, considering the importance of correcting maternal iron deficiency while monitoring for any potential effects on the fetus or infant.

To place an order, submit an enquiry on the Legofer product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Compared with traditional ferrous salts such as ferrous sulfate, Iron Protein Succinylate offers a protein‑bound form that may improve gastrointestinal tolerability and provide more consistent iron absorption. Clinical choice depends on patient tolerance, severity of deficiency, and physician preference.

Legofer should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat, and direct sunlight to maintain stability and potency throughout its shelf life.

Legofer is taken orally, usually with water. It can be taken with or without food, but patients should follow the prescriber’s instructions regarding timing relative to meals or other medications to optimize absorption and reduce gastrointestinal discomfort.

The most serious risks include severe allergic reactions such as anaphylaxis, iron overload from excessive dosing, and rare cases of hypotension. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, swelling, or a sudden drop in blood pressure.

Legofer should be avoided in individuals with known hypersensitivity to Iron Protein Succinylate or any component of the formulation. Caution is also advised for patients with active gastrointestinal bleeding, iron overload disorders, or those receiving medications that may interact significantly with oral iron.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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