Product image of Lekadol Plus C (Ascorbic Acid, Paracetamol) supplied by GNH India

Lekadol Plus C

Active Ingredient:
Ascorbic Acid, Paracetamol
Origin:
EU

Lekadol Plus C (Ascorbic Acid, Paracetamol)

Paracetamol and Ascorbic Acid, the active ingredient in Lekadol Plus C, is an analgesic, antipyretic and vitamin presented as a tablet for oral use. It provides pain relief, reduces fever, and supplies vitamin C to support normal physiological functions in adults and children as appropriate.

GNH India supplies Lekadol Plus C as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics across Europe, Asia, Africa and the Americas worldwide, and meeting local regulatory standards with consistent quality.

Manufacturer / TM Owner

Sandoz D.O.O.

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Indications & Clinical Uses

  • Lekadol Plus C combines paracetamol and vitamin C to address common conditions involving pain, fever, and vitamin C deficiency.
  • Pain: alleviates mild to moderate pain such as headache, musculoskeletal discomfort, or toothache.
  • Fever: reduces elevated body temperature associated with infections or inflammatory processes.
  • Vitamin C deficiency: supplies ascorbic acid to correct low vitamin C levels and support immune function.

How It Works

  • Paracetamol exerts its analgesic and antipyretic actions primarily by inhibiting cyclooxygenase enzymes in the central nervous system, reducing prostaglandin synthesis that mediates pain and fever. Ascorbic acid acts as a water‑soluble antioxidant and cofactor in enzymatic reactions, supporting collagen synthesis and immune cell function. The combination provides symptomatic relief while replenishing vitamin C stores. It also contributes to the body's antioxidant defenses.

Side Effects

Paracetamol and ascorbic acid are generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea or stomach discomfort
  • Headache
  • Skin rash or mild itching
  • Dizziness

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with swelling, difficulty breathing
  • Liver injury, especially with high doses or pre‑existing liver disease
  • Blood disorders such as thrombocytopenia or neutropenia

Precautions & Warnings

Before using Lekadol Plus C, consider the following precautions.

  • Liver disease: avoid or use only under medical supervision due to risk of hepatotoxicity.
  • Alcohol consumption: limit intake as combined effect may increase liver strain.
  • Renal impairment: dose adjustment may be required in patients with reduced kidney function.
  • Hypersensitivity: discontinue use if signs of allergic reaction appear.
  • Pregnancy and breastfeeding: safety not fully established; consult a healthcare professional before use.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Avoid Interactions

Lekadol Plus C may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Other paracetamol‑containing products: risk of overdose and liver toxicity.
  • Strong hepatotoxic drugs (e.g., isoniazid, methotrexate): may compound liver injury.
  • High‑dose alcohol: increases risk of hepatic damage.
  • Warfarin: paracetamol may enhance anticoagulant effect, requiring monitoring.

Moderate Interactions (Monitor Closely)

  • CYP450 enzyme inducers (e.g., rifampicin, carbamazepine): may reduce paracetamol effectiveness.
  • Oral contraceptives: may slightly increase risk of liver enzyme elevation.
  • Antiepileptic drugs (e.g., phenytoin): may affect metabolism of paracetamol.
  • High‑dose vitamin C supplements: may interfere with certain laboratory tests.

Frequently Asked Questions

Lekadol Plus C is indicated for the temporary relief of mild to moderate pain such as headache, toothache, or muscular discomfort, for the reduction of fever associated with common infections, and for supplementation of vitamin C in individuals with low dietary intake or increased physiological demand.

Paracetamol reduces pain and fever by inhibiting cyclooxygenase enzymes in the brain and spinal cord, which lowers the production of prostaglandins—chemicals that sensitize nerve endings to pain and trigger the hypothalamic temperature‑regulating center.

The appropriate dose of Lekadol Plus C is set by a qualified prescriber based on the patient’s age, weight, severity of symptoms, and any underlying health conditions. The prescriber will also consider the total daily intake of paracetamol from all sources to avoid exceeding safe limits.

Safety data for Lekadol Plus C in pregnancy and lactation are limited. Paracetamol is generally considered low risk when used at recommended doses, but the combination with vitamin C has not been specifically evaluated. Women who are pregnant or breastfeeding should consult their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Standard paracetamol tablets contain only the analgesic/antipyretic ingredient, whereas Lekadol Plus C adds ascorbic acid, providing an additional source of vitamin C. This may be advantageous for patients who also need vitamin C supplementation, but the core pain‑relieving and fever‑reducing effects remain comparable to ordinary paracetamol.

Store Lekadol Plus C at ambient temperature, preferably below 25 °C, in its original container to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Lekadol Plus C is intended for oral administration. The tablet should be swallowed whole with a glass of water, unless a prescriber advises otherwise. It is not designed for crushing, chewing, or dissolving, except where specific instructions are provided by a healthcare professional.

The most serious risks include severe allergic reactions such as anaphylaxis, liver injury especially when taken in excess or with other hepatotoxic agents, and rare blood disorders like thrombocytopenia. Immediate medical attention is required if symptoms such as swelling, difficulty breathing, jaundice, or unusual bruising occur.

Individuals with known hypersensitivity to paracetamol, ascorbic acid, or any excipients in the tablet should avoid the product. Patients with severe liver disease, uncontrolled alcohol dependence, or those taking other medications that contain paracetamol should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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