Product image of Lem Plus (Phenylephrine Hydrochloride, Paracetamol, Caffeine) supplied by GNH India

Lem Plus

Active Ingredient:
Phenylephrine Hydrochloride, Paracetamol, Caffeine
Origin:
EU

Lem Plus (Phenylephrine Hydrochloride, Paracetamol, Caffeine)

Phenylephrine Hydrochloride, Paracetamol and Caffeine, the active ingredients in Lem Plus, are a combination of a decongestant, analgesic and stimulant presented as an oral tablet for oral use. It relieves nasal congestion, headache, fever and pain associated with cold or flu in adult patients.

GNH India supplies Lem Plus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory‑compliant documentation for global distribution.

Manufacturer / TM Owner

Aspar Pharmaceuticals Limited

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Indications & Clinical Uses

Lem Plus combines a nasal decongestant, analgesic and stimulant to address symptoms of upper respiratory infections.

  • Nasal congestion: reduces swelling of nasal mucosa to improve airflow.
  • Headache: provides analgesic relief through central COX inhibition.
  • Fever: lowers elevated body temperature via antipyretic action.
  • Pain associated with cold or flu: alleviates muscular and sinus discomfort.

How It Works

  • Phenylephrine hydrochloride acts as an alpha‑adrenergic agonist, causing vasoconstriction of the nasal mucosa and decreasing congestion. Paracetamol provides analgesic and antipyretic effects, likely through central cyclooxygenase inhibition and modulation of the hypothalamic heat‑regulation centre. Caffeine antagonizes adenosine receptors, stimulating the central nervous system and enhancing the analgesic effect of paracetamol while also reducing perceived fatigue.

Side Effects

Common side effects are generally mild and transient.

Common Side Effects

  • Nausea: mild stomach upset.
  • Dizziness: sensation of light‑headedness.
  • Insomnia: difficulty falling or staying asleep.
  • Palpitations: awareness of heartbeat.
  • Increased blood pressure: modest rise in systolic/diastolic values.
  • Headache: paradoxical headache in some users.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, difficulty breathing.
  • Hypertensive crisis: sudden, marked elevation of blood pressure.
  • Liver injury: elevated transaminases or jaundice.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Gastrointestinal bleeding: rare but possible with high paracetamol doses.
  • Seizures: rare, especially with excessive caffeine intake.

Precautions & Warnings

Before using Lem Plus, consider the following safety measures.

  • Cardiovascular disease: avoid if you have uncontrolled hypertension or heart disease.
  • Liver impairment: use with caution in patients with hepatic dysfunction.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Concomitant MAO inhibitors: avoid due to risk of hypertensive reactions.
  • Alcohol consumption: limit intake as it may increase liver load.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Lem Plus may interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors: risk of severe hypertension.
  • Other sympathomimetic decongestants: additive vasoconstrictive effect.
  • Additional paracetamol‑containing products: risk of hepatotoxicity.
  • Certain antidepressants (e.g., tricyclics): may enhance cardiovascular effects.
  • Anticoagulants: caffeine may affect platelet function.

Moderate Interactions (Monitor Closely):\n- Antihypertensive agents: phenylephrine may reduce their efficacy.

  • Caffeine‑rich foods or beverages: may increase stimulant side effects.
  • Alcohol: may potentiate liver toxicity.
  • Anticonvulsants: caffeine may lower seizure threshold.
  • Diuretics: may increase risk of electrolyte imbalance.

Frequently Asked Questions

Lem Plus is an over‑the‑counter oral product that combines phenylephrine, paracetamol and caffeine to relieve nasal congestion, headache, fever and pain associated with common cold or flu in adult patients.

Phenylephrine constricts nasal blood vessels to reduce congestion, paracetamol provides analgesic and antipyretic effects by inhibiting central cyclooxygenase, and caffeine blocks adenosine receptors, stimulating the central nervous system and enhancing the pain‑relieving action of paracetamol.

The appropriate dose of Lem Plus is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and local regulatory guidelines. Patients should follow the prescriber’s instructions and the product label.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using Lem Plus to weigh potential benefits against risks.

To place an order, submit an enquiry on the Lem Plus product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient products, Lem Plus offers a three‑component approach that simultaneously addresses congestion, pain and fatigue. This can provide broader symptom relief than a standalone decongestant or analgesic, but the combination also requires attention to cumulative caffeine or paracetamol exposure.

Lem Plus should be stored at ambient temperature below 25 °C, in its original packaging, and protected from moisture and direct sunlight to maintain potency and stability throughout its shelf life.

Lem Plus is taken orally, usually with a full glass of water. The tablet should be swallowed whole and not chewed or broken, unless otherwise directed by a healthcare professional.

Serious risks include severe allergic reactions, hypertensive crisis, liver injury from excessive paracetamol, and cardiac arrhythmias. Patients experiencing rash, difficulty breathing, sudden high blood pressure, jaundice or irregular heartbeat should seek immediate medical attention.

Lem Plus should be avoided by individuals with known hypersensitivity to any of its ingredients, uncontrolled hypertension, severe cardiovascular disease, significant liver impairment, or those taking monoamine oxidase inhibitors. Children under the recommended age on the label should also not use the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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