Lemocin Gegen Halsschmerzen (Flurbiprofen)

Flurbiprofen is used to alleviate discomfort in the upper respiratory tract and oral cavity.

• Sore throat: provides rapid reduction of pain and inflammation associated with acute pharyngitis.
• Pharyngitis: helps relieve swelling and discomfort during bacterial or viral throat infections.
• Oral pain: eases pain caused by minor mouth injuries, ulcerations, or dental procedures.

• Flurbiprofen exerts its effect by non‑selectively inhibiting cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis reduces inflammation, pain, and fever at the site of application.

Flurbiprofen may cause adverse reactions, ranging from mild to serious.

Common Side Effects

• Nausea or upset stomach
• Dyspepsia or heartburn
• Headache
• Dizziness
• Local irritation of the oral mucosa
• Mild rash

Serious or Rare Side Effects

• Gastrointestinal ulceration or bleeding
• Severe allergic reactions (e.g., Stevens‑Johnson syndrome)
• Renal impairment or reduced kidney function
• Hepatic injury
• Cardiovascular events such as hypertension or thrombotic episodes

Before using Lemocin Gegen Halsschmerzen, consider the following safety measures.

• Hypersensitivity: avoid if the patient has known allergy to flurbiprofen or other NSAIDs.
• Gastrointestinal risk: use with caution in individuals with a history of ulcers or bleeding.
• Renal function: monitor kidney function in patients with existing renal disease.
• Concomitant anticoagulants: assess bleeding risk when taken with warfarin or similar agents.
• Duration of use: do not exceed the recommended short‑term treatment period without medical advice.
• Store at ambient temperature: keep in the original packaging, protect from moisture and direct heat.

Flurbiprofen can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

• Anticoagulants (e.g., warfarin) – increased bleeding risk.
• Other NSAIDs or aspirin – additive gastrointestinal toxicity.
• Corticosteroids – heightened ulcer risk.
• Lithium – elevated lithium serum levels.
• Methotrexate – reduced clearance, potential toxicity.

Moderate Interactions (Monitor Closely)

• ACE inhibitors or ARBs – possible reduction in renal function.
• Diuretics – may impair kidney function when combined.
• SSRIs or SNRIs – increased bleeding tendency.
• Antihypertensives – potential attenuation of blood‑pressure control.
• Oral hypoglycemics – may affect glucose regulation.