Lemon Balm Holland & Barrett (Melissa Leaf Dry Extract)

• Lemon Balm (Melissa officinalis) is used primarily for mild nervous system and digestive support.
• Mild anxiety: helps promote a feeling of calm and reduce occasional nervous tension.
• Sleep disturbances: may aid in achieving more restful sleep when taken in the evening.
• Occasional digestive discomfort: supports normal gastrointestinal function and reduces mild bloating.
• Stress‑related irritability: may lessen irritability during periods of mental stress.
• Tension‑type headache: may provide mild relief for tension‑type headaches.

• Melissa leaf contains rosmarinic acid, flavonoids, and volatile oils that exhibit antioxidant and mild GABA‑ergic activity. These constituents are thought to modulate neuronal excitability and reduce cortisol release, contributing to a calming effect and supporting normal sleep patterns, while also exerting mild antispasmodic activity on the gastrointestinal tract.

Lemon Balm is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects

• Mild gastrointestinal upset: occasional nausea or stomach discomfort.
• Headache: transient mild headache in some individuals.
• Dizziness: brief sensation of light‑headedness.
• Dry mouth: reduced salivation.
• Fatigue: feeling of mild tiredness.

Serious or Rare Side Effects

• Allergic reaction: rash, itching, or swelling.
• Difficulty breathing: signs of anaphylaxis require immediate medical attention.
• Liver enzyme elevation: rare reports of increased hepatic enzymes; monitor if pre‑existing liver disease.

• Before using Lemon Balm, consider the following safety points.
• Pregnancy: safety not established; consult a healthcare professional before use.
• Breastfeeding: limited data; use with caution.
• Drug interactions: may potentiate the effects of CNS depressants; monitor sedation.
• Medical conditions: caution in patients with thyroid disorders due to possible iodine content.
• Children: not recommended without medical advice.
• Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Lemon Balm may interact with other medicines; awareness of the level of interaction is important.

Major Interactions (Avoid)

• CNS depressants: may increase sedation.
• Antithyroid drugs: may interfere with thyroid hormone synthesis.
• Anticoagulants: potential additive effect on bleeding risk.

Moderate Interactions (Monitor Closely)

• Antihistamines: may enhance drowsiness.
• Antidepressants (SSRIs): possible additive effect on serotonin levels.