Product image of Lemsip Cold & Flu Lemon (Phenylephrine Hydrochloride, Paracetamol) supplied by GNH India

Lemsip Cold & Flu Lemon

Active Ingredient:
Phenylephrine Hydrochloride, Paracetamol
Origin:
EU

Lemsip Cold & Flu Lemon (Phenylephrine Hydrochloride, Paracetamol)

Phenylephrine Hydrochloride and Paracetamol, the active ingredient in Lemsip Cold & Flu Lemon, is a phenylephrine (decongestant) and paracetamol (analgesic, antipyretic) presented as an oral powder for solution (effervescent sachet) for oral use. It provides relief of nasal congestion, fever, headache and body aches associated with cold and flu in adults and children.

GNH India supplies Lemsip Cold & Flu Lemon as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare (Uk) Ltd

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Indications & Clinical Uses

  • Phenylephrine Hydrochloride and Paracetamol act on the respiratory and pain pathways to alleviate common cold and flu symptoms.
  • Nasal congestion: reduces swelling of nasal mucosa, easing breathing.
  • Fever: lowers elevated body temperature.
  • Headache and body aches: relieves pain associated with viral upper respiratory infection.

How It Works

  • Phenylephrine Hydrochloride is a selective α1‑adrenergic receptor agonist that constricts blood vessels in the nasal mucosa, decreasing swelling and congestion. Paracetamol acts centrally by inhibiting prostaglandin synthesis, likely via COX enzymes, which produces analgesic and antipyretic effects, reducing pain and fever.

Side Effects

Phenylephrine Hydrochloride and Paracetamol may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Nausea
  • Stomach discomfort
  • Dizziness
  • Insomnia

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Significant increase in blood pressure
  • Liver enzyme elevation or hepatic injury

Precautions & Warnings

When using Phenylephrine Hydrochloride and Paracetamol, certain precautions should be observed to minimise risk.

  • Do not exceed the recommended daily dose: follow prescriber or label instructions.
  • Avoid if you have known hypersensitivity to phenylephrine, paracetamol or any excipients.
  • Caution in hypertension: phenylephrine may raise blood pressure, monitor if you have cardiovascular disease.
  • Limit use with other decongestants or sympathomimetic agents: additive effects may occur.
  • Consult a healthcare professional if pregnant, planning pregnancy, or breastfeeding.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Phenylephrine Hydrochloride and Paracetamol can interact with other medicines; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid)

  • MAO inhibitors: may cause hypertensive crisis when combined with phenylephrine.
  • Other phenylephrine or decongestant products: risk of excessive vasoconstriction and elevated blood pressure.
  • Warfarin: paracetamol can enhance anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely)

  • Alcohol: combined use may increase liver strain and risk of hepatotoxicity.
  • Other hepatotoxic drugs (e.g., isoniazid, certain antiepileptics): monitor liver function.
  • Antihypertensive agents (beta‑blockers, ACE inhibitors): phenylephrine may reduce their efficacy.

Frequently Asked Questions

Lemsip Cold & Flu Lemon is formulated to provide symptomatic relief of common cold and flu. It targets nasal congestion, fever, headache and general body aches, helping individuals feel more comfortable while the underlying viral illness runs its course.

Phenylephrine is a selective α1‑adrenergic receptor agonist. By stimulating these receptors on the blood vessels of the nasal mucosa, it causes vasoconstriction, which reduces swelling and opens the nasal passages, making breathing easier during a cold or flu.

The appropriate dose is determined by a prescriber or according to the product label. Dosage may vary based on age, weight, and clinical condition, and should never exceed the maximum daily amount indicated on the packaging.

Safety data are limited, and the pregnancy category is not definitively established. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with a healthcare professional before taking the product.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The primary alternative is pseudoephedrine, another oral decongestant. Phenylephrine generally has a shorter duration of action and may be less potent in severe congestion, but it is widely available OTC and has a lower risk of certain cardiovascular side effects compared with pseudoephedrine.

Store the sachets below 25 °C in a dry place. Keep them in the original packaging to protect from moisture and direct sunlight. Do not refrigerate or freeze the product.

The product is supplied as an effervescent powder. Dissolve one sachet in a glass of warm (not boiling) water, stir until fully dissolved, and drink the solution as directed. It is taken orally.

Serious risks include severe allergic reactions such as anaphylaxis, a marked rise in blood pressure especially in individuals with hypertension, and rare liver injury indicated by elevated liver enzymes. Immediate medical attention is required if any of these occur.

Individuals with known hypersensitivity to phenylephrine, paracetamol, or any excipients should avoid the product. It is also contraindicated in patients with uncontrolled hypertension, severe coronary artery disease, or those taking monoamine‑oxidase inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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