Product image of Lemsip Decongestant & Flu (Phenylephrine Hydrochloride, Paracetamol, Caffeine) supplied by GNH India

Lemsip Decongestant & Flu

Active Ingredient:
Phenylephrine Hydrochloride, Paracetamol, Caffeine
Origin:
EU

Lemsip Decongestant & Flu (Phenylephrine Hydrochloride, Paracetamol, Caffeine)

Phenylephrine Hydrochloride, Paracetamol and Caffeine, the active ingredients in Lemsip Decongestant & Flu, are a combination analgesic, antipyretic and nasal decongestant presented as an oral combination for oral use. It provides relief of cold and flu symptoms such as fever, headache, body aches and nasal congestion in adults and children.

GNH India supplies Lemsip Decongestant & Flu as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Ireland Ltd.

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Indications & Clinical Uses

Lemsip Decongestant & Flu, a combination analgesic and nasal decongestant, is used to manage symptoms of upper respiratory infections and influenza.

  • Cold and flu: provides symptomatic relief of fever, aches, and general discomfort.
  • Nasal congestion: reduces swelling of nasal mucosa to improve airflow.
  • Fever: lowers elevated body temperature.
  • Headache: alleviates pain associated with viral illness.

How It Works

  • Phenylephrine acts as an alpha‑adrenergic agonist causing vasoconstriction of the nasal mucosa, which eases congestion. Paracetamol inhibits central prostaglandin synthesis, delivering analgesic and antipyretic effects. Caffeine antagonises adenosine receptors and potentiates the analgesic action of paracetamol, enhancing overall symptom relief.

Side Effects

Common side effects are generally mild and transient.

Common Side Effects

  • Nausea: occasional stomach upset.
  • Dizziness: light‑headed sensation.
  • Insomnia: difficulty falling asleep.
  • Mild headache: transient head pain.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe skin eruption: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Liver enzyme elevation: potential hepatic stress.
  • Cardiovascular events: rapid heart rate or high blood pressure.

Precautions & Warnings

Before using Lemsip Decongestant & Flu, consider the following precautions.

  • Pregnancy: consult a healthcare professional before use.
  • Liver disease: use with caution due to paracetamol content.
  • Hypertension: phenylephrine may raise blood pressure.
  • Drug interactions: avoid concurrent use with MAO inhibitors or other sympathomimetics.
  • Children: follow age‑appropriate dosing guidelines.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Lemsip Decongestant & Flu can interact with several medicines; review the categories below.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis.
  • Other sympathomimetics: may cause excessive vasoconstriction.
  • Anticoagulants: paracetamol may increase bleeding tendency.
  • Certain antihypertensives: phenylephrine may counteract blood‑pressure control.

Moderate Interactions (Monitor Closely)

  • Caffeine‑containing products: may increase stimulant effects.
  • CYP450 substrates: caffeine can alter metabolism of some drugs.
  • Alcohol: may increase hepatic load and risk of liver injury.

Frequently Asked Questions

Lemsip Decongestant & Flu is an over‑the‑counter oral product that combines phenylephrine, paracetamol and caffeine to relieve common cold and flu symptoms such as fever, headache, body aches, and nasal congestion.

Phenylephrine is an alpha‑adrenergic agonist that narrows the blood vessels in the nasal passages, reducing swelling and improving airflow, which helps to relieve nasal congestion.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight and clinical condition. Patients should follow the prescriber’s instructions and the product label.

Pregnant or breastfeeding individuals should consult their healthcare provider before using this product, as the safety of phenylephrine, paracetamol and caffeine may depend on the stage of pregnancy and infant exposure.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with single‑ingredient products, Lemsip combines a decongestant, an analgesic/antipyretic and a stimulant, offering broader symptom coverage in one dose. Alternatives may contain only one of these actions, requiring multiple products for comparable relief.

Store the product at ambient temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and excessive heat to maintain stability.

The medication is taken orally, usually as a dissolved powder or liquid preparation, according to the dosage instructions provided by the prescriber or printed on the label.

Serious risks include allergic reactions such as rash, swelling or breathing difficulty, severe skin reactions, significant liver enzyme elevation from paracetamol, and cardiovascular effects like high blood pressure or rapid heart rate from phenylephrine.

Individuals with known hypersensitivity to any of the ingredients, uncontrolled hypertension, severe liver disease, or those taking contraindicated medications such as MAO inhibitors should avoid using this product unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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