Lemsip Max Plus Cold & Flu Relief (Phenylephrine Hydrochloride, Paracetamol, Caffeine)

Lemsip Max Plus combines phenylephrine, paracetamol and caffeine to address multiple cold‑and‑flu symptoms.

• Nasal congestion: reduces swelling of nasal mucosa to improve airflow.
• Fever: lowers elevated body temperature.
• Headache: alleviates pain associated with viral illness.
• Sore throat: eases discomfort and irritation in the throat.

• Phenylephrine hydrochloride acts as an α1‑adrenergic receptor agonist, causing vasoconstriction of nasal mucosal vessels and reducing congestion. Paracetamol provides analgesic and antipyretic effects primarily through inhibition of central cyclooxygenase enzymes, lowering prostaglandin synthesis. Caffeine antagonizes adenosine receptors, enhancing paracetamol’s analgesic action and providing mild central nervous system stimulation.

Adverse reactions may occur with any medication and should be monitored.

Common Side Effects

• Nausea: mild stomach upset.
• Dizziness: transient light‑headedness.
• Insomnia: difficulty falling asleep.
• Headache: mild to moderate pain.
• Dry mouth: reduced salivation.
• Palpitations: sensation of rapid heartbeat.

Serious or Rare Side Effects

• Severe allergic reaction: rash, swelling, difficulty breathing.
• High blood pressure: sudden increase in systolic/diastolic values.
• Cardiac arrhythmia: irregular heart rhythm.
• Liver injury: jaundice, elevated liver enzymes.
• Stevens‑Johnson syndrome: severe skin blistering.
• Anaphylaxis: life‑threatening systemic reaction.

Use Lemsip Max Plus with awareness of specific safety considerations.

• Do not exceed recommended dose: follow prescriber or label instructions.
• Avoid use in uncontrolled hypertension: phenylephrine may raise blood pressure.
• Consult a healthcare professional if taking MAO inhibitors: risk of hypertensive crisis.
• Use with caution in liver disease: paracetamol metabolism may be impaired.
• Pregnancy and breastfeeding: seek medical advice before use.
• Store at room temperature: keep in the original pack, protect from moisture.

Lemsip Max Plus may interact with other medicines; awareness helps prevent adverse events.

Major Interactions (Avoid)

• MAO inhibitors: risk of severe hypertension.
• Other phenylephrine or sympathomimetic agents: additive vasoconstriction.
• Additional paracetamol‑containing products: risk of hepatotoxicity.

Moderate Interactions (Monitor Closely):\n- Antihypertensive drugs: phenylephrine may reduce their effectiveness.

• Antidepressants (SSRIs, SNRIs): possible increase in serotonin levels.
• Antidiabetic agents: caffeine may affect glucose control.
• Alcohol: may enhance liver strain and sedation.